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Blood pressure and other metabolic syndrome factors and risk of brain tumour in the large population-based Me-Can cohort study.

OBJECTIVES:: Brain tumour has few established determinants. We assessed to which extent risk of brain tumour was related to metabolic syndrome factors in adults. METHODS:: In the Me-Can project, 580 000 individuals from Sweden, Austria, and Norway were followed for a median of 10 years after baseline measurement. Data on brain tumours were obtained from national cancer registries. The factors of m

Windstorms in Sweden - variations and impacts

Windstorms have caused severe damage on several occasions in Sweden during the last century. A general concern about future projections of climate extremes has raised questions on the variations and impacts of windstorms. The main objective with this work was to reach a deeper understanding of the variability and possible trends in ­windstorms, and related storm impacts in forests. This was achiev

Beställarkompetens vid upphandling och utveckling av IT – Om kompetensframväxt i skuggan av kunskapsfragmentering

Ever since IT started to become important and strategic assets in organizational practices, systems acquisitions have been a challenging and complex endeavor. There are seemingly never ending reports of unsuccessful IT acquisitions and lack of systems acquisition competence (beställarkompetens in Swedish). The aim of this thesis is to shed deeper light on what systems acquisition competence is abo

Regeringsformen och förvaltningen - styrning och rättslig reglering

Artikeln utgör en presentation av forskningsprojektet Regeringsformen och förvaltningen – styrning och rättslig reglering, för vilket Vetenskapsrådet har beviljat medel. Projektet syftar till att undersöka styrningen av den svenska förvaltningen ur ett rättsligt perspektiv. Huvudfokus är styrningen och den rättsliga regleringen idag, men för att förstå den, studeras den ur ett utvecklingsperspekti

Recension: Teckenspråkiga döva. Identitetsförändringar i det svenska dövsamhället.

Omdöme ”Teckenspråkiga döva” är en rik avhandling. Den innehåller spännande och djuplodande empiriskt material. Fredäng täcker samtidigt in ett stort fält från individnivå med familj och skola till lokalföreningar och riksorganisation och till hur samhället ställer sig i olika frågor. Det är sannolikt att de sociala typer som Päivi Fredäng tar upp, om hur döva ser på sig själva och sin dövhet l

Objectively measured daily physical activity related to cardiac size in young children.

Training studies in children have suggested that endurance training can give enlargement of cardiac dimensions. This relationship has not been studied on a population-based level in young children with objective methods. A cross-sectional study was made of 248 children (140 boys and 108 girls), aged 8-11 years, from a population-based cohort. Left ventricular end-diastolic diameter (LVDD) and left

Gene therapy for dopamine replacement.

Dopamine replacement for Parkinson's disease (PD) have seen three major iterations of improvements since the introduction of l-3,4-dihydroxyphenylalanine (l-DOPA) pharmacotherapy: dopamine receptor agonists, ex vivo gene transfer for cell transplantation and most recently in vivo gene therapy. In this chapter, we describe the principles behind viral vector-mediated enzyme replacement in PD. We foc

Effects of Prostate-Specific Antigen Testing on Familial Prostate Cancer Risk Estimates.

Background Family history is a strong risk factor for prostate cancer. The aim of this study was to investigate whether increased diagnostic activity is related to the incidence of prostate cancer among brothers of men with prostate cancer. Methods Data were from the nationwide population-based Prostate Cancer Database Sweden (PCBaSe Sweden), which includes data from the National Prostate Cancer R