Calpain-Mediated Apoptosis in Motor Neurons of Adult Mouse Spinal Cord Slices
Motor neuron degeneration is a critical phenomenon during spinal cord injuries and some neurodegenerative diseases. However, the mechanisms by which cell death is induced in these neurons are poorly understood. One reason for this, is the lack of model systems in which the survival and death of adult motor neurons can be studied under controlled conditions. This thesis is an attempt to develop suc
