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The progressive development of Alzheimer's disease (AD) pathology follows a spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP) with the arctic (E693G) mutation, pathology spreads along anatomically connected structures. Amyloid-β (Aβ) pathology first appears in the subiculum and is later detected in interconnected brain regi

We prove sharp estimates for the Bergman projection in weighted Bergman spaces in terms of the Bekolle constant. Our main tools are a dyadic model dominating the operator and an adaptation of a method of Cruz-Uribe, Martell and Perez. (C) 2013 Elsevier Inc. All rights reserved.

Organ transplantation may lead to secondary osteoporosis in children. This study characterized bone histomorphometric findings in pediatric solid organ transplant recipients who were assessed for suspected secondary osteoporosis. Iliac crest biopsies were obtained from 19 children (7.6-18.8 years, 11 male) who had undergone kidney (n = 6), liver (n = 9), or heart (n = 4) transplantation a median 4

To validate cardiac output measurements by ultrasound dilution technology (COstatus monitor) against those obtained by a transit-time ultrasound technology with a perivascular flow probe and to investigate ultrasound dilution ability to estimate pulmonary to systemic blood flow ratio in children.

Background: When compared to the other mismatch repair genes involved in Lynch syndrome, the identification of mutations within PMS2 has been limited (<2% of all identified mutations), yet the immunohistochemical analysis of tumour samples indicates that approximately 5% of Lynch syndrome cases are caused by PMS2. This disparity is primarily due to complications in the study of this gene caused by

Objective To determine if the prediction of the Malignancy of all adnexal mass using pattern recognition, i.e. subjective evaluation of gray-scale and Doppler ultrasound findings, is as accurate when based on static images as it is when based on a real-time ultrasound examination. Methods The static images of 166 non-consecutive patients with 'difficult' adnexal masses, who all underwent surgery a

Industry involvement in open source software development has become a popular practice among companies which, e.g., share software development costs with other community participants or implement an open source based business model. An increased understanding of the underlying development structure, especially in a case where the community participants are composed of competing industry members, c

We investigate electrical properties of self-assembled branched InAs nanowires. The branched nanowires are catalytically grown using chemical beam epitaxy, and three-terminal nanoelectronic devices are fabricated from the branched nanowires using electron-beam lithography. We demonstrate that, in difference from conventional macroscopic junctions, the fabricated self-assembled nanowire junction de

Abstract in UndeterminedJavaScript has gone from being a mechanism for providing dynamic web pages to an important component of many web applications. Currently one of the most popular type of web applications is so-called social networks, e.g., Facebook, Twitter, and MySpace. However, the workload and execution behavior of JavaScript in this context have not been fully explored or understood.In t

The aim of this paper is to integrate spatial cognition with lexical semantics. We develop cognitive models of actions and events based on conceptual spaces and vectors on them. The models are then used to present a semantic theory of verbs. We propose a two-vector model of events including a force vector and a result vector. We argue that our framework provides a unified account for a multiplicit

We report the measurement of cumulants (C-n,n = 1, ..., 4) of the net-charge distributions measured within pseudorapidity (vertical bar eta vertical bar < 0.35) in Au + Au collisions at root s(NN) = 7.7-200 GeV with the PHENIX experiment at the Relativistic Heavy Ion Collider. The ratios of cumulants (e.g., C-1/C-2, C-3/C-1) of the net-charge distributions, which can be related to volume independe

Background: In 2007, the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) issued recommendations on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. Objective: We investigated whether concordance with WCRF/AICR recommendations is related to risk of death. Design: The

An important regulatory suppressive function in autoimmune and other inflammatory processes has been ascribed to CD4(+) Foxp3(+) regulatory T cells (Tregs), which requires direct cell-cell communication between Tregs, effector T cells, and APCs. However, the molecular basis for these interactions has not yet been clarified. We show here that sialoadhesin (Sn), the prototype of the siglec family of

Den 6 december 2012 kom EU-domstolens dom i målet. Den omfattar 206 domsmotiv mot tribunalens 920 – således ett relativt sett lättillgängligt aktstycke, vilket också ligger i sakens natur med den begränsade talerätten vid överprövning. AZ yrkade att kommissionens beslut skulle ogiltigförklaras på grund av: (i) tribunalens felaktiga rättstillämpning vad gällde fastställandet av den relevanta markna

Preparation of a new type of cryostructured carbon particle macroporous gel with one-step sub-zero cross-linking was studied in this work. Aggregation of nano-and micro-particles of poly(N-isopropylacrylamide-co-allylamine) was used to form a polymeric network to integrate activated carbon particles. The cryostructured particle gel was compared with the conventional composite cryogel. The unique m

Lärosäten Syd är ett nära och formaliserat samarbete mellan de fem skånska och blekingska lärosätena, nämligen Blekinge Tekniska Högskola, Högskolan Kristianstad, Lunds universitet Malmö högskola och SLU/Alnarp, Figur 1. Universitet och högskolor har på ett nytt sätt blivit väsentliga regionala aktörer med ett stort ansvar inom ett antal viktiga områden som tillväxt, industri, kultur och arbetsmar

Sweden's connections to and relationships with the European and wider world is a field of study attracting considerable scholarly attention. The essays here, from archaeologists and historians, offer a new perspective on early modern Sweden as deeply affected by the increasing internationality of the 16th-18th centuries. Set in the socio-political context of an expanding and changing kingdom, they