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Prolactin binding to the prolactin receptor exerts pleiotropic biological effects in vertebrates. The prolactin receptor (PRLR) has multiple isoforms due to alternative splicing. The biological roles and related signaling of the long isoform (PRLR-LF) have been fully elucidated. However, little is known about the short isoform (PRLR-SF), particularly in cancer development and metabolic reprogrammi

Peatlands play an important role in the global carbon cycle as they contain a large soil carbon stock. However, current climate change could potentially shift peatlands from being carbon sinks to carbon sources. Remote sensing methods provide an opportunity to monitor carbon dioxide (CO2) exchange in peatland ecosystems at large scales under these changing conditions. In this study, we developed ePeatlands play an important role in the global carbon cycle as they contain a large soil carbon stock. However, current climate change could potentially shift peatlands from being carbon sinks to carbon sources. Remote sensing methods provide an opportunity to monitor carbon dioxide (CO2) exchange in peatland ecosystems at large scales under these changing conditions. In this study, we developed e

INTRODUCTION: Chemoprevention against colorectal cancer (CRC) is greatly needed. As the development of CRC involves multiple dysfunctional pathways, it is thus reasonable to combine some agents that address several pathways to achieve better chemoprotection. We aimed to explore whether the use of aspirin and selective serotonin reuptake inhibitors (SSRIs)-either as monotherapy or combined-can have

Investigating the Galactic center offers unique insights into the buildup and history of our Galaxy and is a stepping stone to understand galaxies in a larger context. It is reasonable to expect that the stars found in the Galactic center might have a different composition compared to stars found in the local neighborhood around the Sun. It is therefore quite exciting when recently there were repo

Ecosystem respiration is a major component of the global terrestrial carbon cycle and is strongly influenced by temperature. The global extent of the temperature–ecosystem respiration relationship, however, has not been fully explored. Here, we test linear and threshold models of ecosystem respiration across 210 globally distributed eddy covariance sites over an extensive temperature range. We fin

There are several formulations for calculating the Q factors of antennas. The evaluated Q factors are not always in agreement because of the differences in the definition of Q factor and the method in addressing the stored reactive energies. This paper gives a short comparison of five of them with numerical examples.

In this paper we consider spatial coupling in turbo equalization and demonstrate that the code design trade-off between the performance in waterfall and error floor regions can be avoided. We introduce three coupling schemes and compare their performances, where the first method introduces coupling between the encoder and the channel, while the second uses a spatially coupled (SC) code. In the thi

A Large Intelligent Surface (LIS) is a recently proposed concept, especially suitable for high speed indoor communications and industrial internet of things (IoT) applications. Basing the LIS on smaller panels has clear advantages in terms of flexibility and mass production of its elements. In this paper we consider a panel-based LIS and we study the interplay of the panel size, the number of base

With different activities in a room, room acoustic requirements differ and when the acoustic requirements are different, acoustic treatment must be adapted. This study focuses on room acoustics in ordinary public rooms such as classrooms and offices. By tradition the acoustic treatment in these rooms is an absorbent ceiling. Experiments have been carried out in a classroom where the baseline in th

Revision of the Task Force diagnostic criteria (TFC) for arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), in 2010, has increased the sensitivity for the diagnosis of early and familial forms of the disease. Epsilon wave (EW) is a major diagnostic criterion in the context of ARVC/D, however, it remains unquantifiable and therefore, may leave room for substan-tial subjective inter

Background Female sex is known to have increased perioperative mortality in cardiac surgery. Studies reporting effects of sex on outcome following surgical repair for acute Type A aortic dissection (ATAAD) have been limited by small cohorts of heterogeneous patient populations and have shown diverging results. This study aimed to compare perioperative characteristics, operative management, and pos

In 1998, on the brink of a great public effort that by now has delivered the sequences of thousands of genomes and has annotated these genomes by translating tens of thousands of 3D protein domain structures from their coding sequences, Ernst Mayr and Carl Woese engaged in a debate. At issue were the virtues of phenotypic contra genotypic approaches to phylogeny and taxonomy. Though not conclusive

This paper studies entrepreneurship ecosystem development in a context little discussed in the extant literature to date: Oman. Specifically, it focuses on business incubation (BI) initiatives as a policy tool for developing the local, regional, and national systems of supporting entrepreneurship and SME growth. Although BI’s are a popular policy measure for ecosystem development, spreading global

Dansmästarna vid Lunds universitet från 1600-talet till 1800-talet. Höviska bildningsideal. Lunds universitets historia.

PURPOSE: The "Shrunken pore syndrome" (SPS) is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatinC /eGFRcreatinine -ratio. Studies have demonstrated a high risk for cardiovascular morbidity and mortality for patients with SPS. In this discovery study, we explored associations between SPS and proteins implicated in cardiovascular dis

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