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Background: Second primary cancers (SPCs) are important clinically as they may negatively influence patient survival and they may tell about therapeutic side effects and general causes of cancer. Population-based literature concerning SPCs after hepatobiliary cancers is limited and here we assess risks of SPCs after hepatocellular cancer (HCC), and cancers of the gallbladder, bile ducts and ampull

Objective: Injuries to the wrist are, due to its small size and complex anatomical structures, difficult to assess by MR, and surgical interventions such as diagnostic arthroscopy are often necessary. Therefore, improved visualization using non-invasive methods could be of clinical value. As a first step of improvement, the purpose of this study was to evaluate visualization of anatomical structur

ObjectiveThe proportion of older people is increasing and reflects in the demand on ambulance services (AS). Patients can be more vulnerable and increasingly dependent, especially when their decision-making ability is impaired. Self-determination in older people has a positive relation to quality of life and can raise ethical conflicts in AS. Hence, the aim of this study was to empirically explore

Party politics and electoral research generally assume that party members are loyal voters. This article first assesses the empirical basis for this assumption before providing individual-level explanations for defection. It combines prominent theories from party politics and electoral behaviour research and argues that internal disagreement and external pressure can each bring about disloyal voti

Does ideological incongruence hurt parties in elections? Research on the representational relationship between parties and voters suggests that ideological congruence can boost a party’s electoral prospects. However, while the mechanism is at the individual-level, most of the literature focuses on the party-level. In this article, we develop a set of hypotheses based on a multi-issue conception of

In Europe, noneconomic political issues are seen as secondary but significant aspects of political competition. There is uncertainty, however, about the sources of the varying relationships between economic and cultural politics. This article explains the variance in the correlation of the economic and cultural dimensions in different party systems through the impact of historical religious confli

Do radical right parties present blurry economic stances, or have they clarified their positions while moving towards the economic left? This article questions the strategic behaviour of radical right parties in Western Europe. It shows that although radical right parties have increased their discussion of economic issues, and expert placements of this party family on the economic dimension have b

Alzheimer’s disease (AD) is characterized by the spread of tau pathology throughout the cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals, although recent work has demonstrated substantial variability in the population with AD. Using tau-positron emission tomography scans from 1,612 individuals, we identified 4 distinct spatiotemporal trajectories of ta

To what extent do representational gaps between parties and voters destabilise party systems and create electoral opportunities for anti-establishment parties on the left and right? In this paper, we use multiple measures of party-partisan incongruence to evaluate whether issue-level incongruence contributes to an increase of political disaffection and anti-establishment politics. For this analysi

At field strengths of 7 T and above, T1-weighted imaging of human brain suffers increasingly from radiofrequency (RF) B1 inhomogeneities. The well-known MP2RAGE (magnetization prepared two rapid acquisition gradient echoes) sequence provides a solution but may not be readily available for all MR systems. Here, we describe the implementation and evaluation of a sequential protocol to obtain normali

Using survey vignettes and scaling techniques, we estimate common socio-cultural and European integration dimensions for political parties across the member states of the European Union. Previous research shows that party placements on the economic left-right dimension are cross-nationally comparable across the EU; however, the socio-cultural dimension is more complex, with different issues formin

This issue of the AILA Review focuses on transdisciplinarity as the key to developing shared languages in and across domains and professional settings. The relationship and collaboration between researchers and practitioners have long been discussed within and across applied sciences and theoretical disciplines, mainly in the framework of transdisciplinarity (see AILA Review 31, 2018, for a recent

Are political parties in young democracies responsive to the policy preferences of the public? Compared to extensive scholarship on party responsiveness in established democracies, research on party responsiveness in young democracies is limited. We argue that weaker programmatic party–voter linkages in post-communist democracies create incentives for parties to respond to their supporters rather

This study evaluates the spatial and temporal performance of the Climate Hazard Group InfraRed Precipitation Satellite (CHIRPS) against Tropical Rainfall Measuring Mission (TRMM) Multi-Satellite Precipitation Analysis (TMPA) 3B42/3B43 v. 7 and Global Precipitation Measurement (GPM)-based Integrated Multi-Satellite Retrievals for GPM (IMERG V06), from 2000 to 2013. Several statistical metrics were

Research on party responsiveness in established democracies suggests that parties follow shifts in the preferences of either the general electorate or party supporters. Drawing on theoretical models of party competition and research on party-voter congruence, we argue in this article that in the 21st century Western European mainstream parties respond to their partisan constituents. Parties adjust

BACKGROUND Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS In an open-label trial with blinded assessment of outcomes, we randomly assigned 1900 adults with coma who had had an out-of-hospital cardiac arrest of presumed cardiac or unknown cause to undergo targeted hypothermia at 33°C, followed by controlled

Avian communities play a pivotal role in Arctic ecosystems and birds have become the key model taxa for climate change research. Due to funding priorities, Arctic passerines have been studied less intensively than waterfowl and shorebirds. In our study, we aim to partly fill this gap and look at the change in passerine community species composition in the Chaun River Delta in Northeast Siberia (68

The objective of this study is to explore the inclusiveness of lesbian, gay, bisexual, transgender, and queer (LGBTQ) adolescents in junior high school from the perspective of LGBTQ adolescents in Sweden. Semi-structured in-depth interviews were conducted with 10 GBTQ adolescents, aged 16 to 19. The study was approved by the Swedish Ethical Review Authority (Dnr: 2019-03816). A Braun and Clark ins