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Elevated levels of protein AMBP in cerebrospinal fluid of women with preeclampsia compared to normotensive pregnant women

Purpose: To investigate the cerebrospinal fluid (CSF) proteome of patients with preeclampsia (PE) and normotensive pregnant women, in order to provide a better understanding of brain involvement in PE. Experimental design: Ninety-eight CSF samples (43 women with PE and 55 normotensive controls) were analyzed by LC–MS/MS proteome profiling. CSF was obtained during the spinal puncture before caesare

Two-Dimensional Platform for Networks of Majorana Bound States

We model theoretically a two-dimensional electron gas (2DEG) covered by a superconductor and demonstrate that topological superconducting channels are formed when stripes of the superconducting layer are removed. As a consequence, Majorana bound states (MBSs) are created at the ends of the stripes. We calculate the topological invariant and energy gap of a single stripe, using realistic values for

Absorption and Quantum Yield of Single Conjugated Polymer Poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) Molecules

We simultaneously measured the absorption and emission of single conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) molecules in a poly(methyl methacrylate) (PMMA) matrix using near-critical xenon to enhance the photothermal contrast for direct absorption measurements. We directly measured the number of monomers and the quantum yield of single conjugated polymer

On the renormalization of contact interactions for the configuration-interaction method in two-dimensions

The configuration interaction (CI) method for calculating the exact eigenstates of a quantum-mechanical few-body system is problematic when applied to particles interacting through contact forces. In dimensions higher than one the approach fails due to the pathology of the Dirac δ-potential, making it impossible to reach convergence by gradually increasing the size of the Hilbert space. However, t

Carbon balance of a grazed savanna grassland ecosystem in South Africa

Tropical savannas and grasslands are estimated to contribute significantly to the total primary production of all terrestrial vegetation. Large parts of African savannas and grasslands are used for agriculture and cattle grazing, but the carbon flux data available from these areas are limited. This study explores carbon dioxide fluxes measured with the eddy covariance method for 3 years at a graze

A convenient setup for laser-induced fluorescence imaging of both CO and CO2 during catalytic CO oxidation

In-situ knowledge of the gas composition close to a catalyst is essential for a better understanding of the gas–surface interaction. With planar laser-induced fluorescence (PLIF), the gas distribution around an operating catalyst can be visualized with high spatial and temporal resolution, in a non-intrusive manner. We report on a convenient setup using a nanosecond YAG-Dye laser system together w

Oxidative challenges of avian migration : A comparative field study on a partial migrant

Most avian migrants alternate flight bouts, characterized by high metabolic rates, with stopovers, periods of fuel replenishment through hyperphagia. High-energy metabolism and excessive calorie intake shift the balance between damaging prooxidants and antioxidants toward the former. Hence, migration likely affects the oxidative balance of birds. Migratory flight indeed appears to cause oxidative

“I feel like I do not exist” : Adolescent Dissociative Experiences and the Importance of Trauma Type, Attachment, and Migration Background

Vissa ungdomar som upplevt potentiellt traumatiserande händelser kan utveckla dissociationssymptom. Under gynnsamma förhållanden har människor en förmåga att integrera känslor, tankar, sinnesintryck och minnen av livshändelser in i en adaptiv och sammanhängande självbild och berättelse om självet. Dissociation i samband med trauma kan beskrivas som ett sammanbrott av denna förmåga. Dissociativa upAfter experiencing potentially traumatic events (PTEs) some adolescents develop pathological dissociation. Trauma-related dissociation can be described as a break-down of the individual’s capacity to integrate emotions, thoughts, sensations, and memories about traumatic or other events into an adaptive and coherent self-image and self-narrative. Dissociative experiences (DE) include experienced lo

Recognition : A Short History

During the past decade there has been a resurgence of interest in the concept of recognition in international theory. Once the narrow concern of social theorists, the concept of recognition is nowadays invoked in at least three different senses in order to explain three different things. First, it is commonly used to explain how states and their identities are shaped by interaction, and how the mo

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy, whereas in tumors establishing new blood supplies is considered a key step in supporting metastases. Therefore the development of novel angiogenesis

Sorting red blood cells by their dynamical properties

A combination of mesoscale hydrodynamic simulations and microfluidic experiments are used to explore the use of cells' mechanical and dynamical properties as biomarkers for separation. Dynamic behaviour of red blood cells (RBCs) within deterministic lateral displacement (DLD) devices is investigated within various array geometries and for different viscosity contrasts between the intra- and extra-

Theory of the acoustic force density acting on inhomogeneous fluids

We derive an expression for the acoustic force density acting on an inhomogeneous fluid with a continuous spatial variation in density and compressibility. A key prediction of our theory, validated by confocal imaging in an acoustofluidic microchip, is that inhomogeneous fluid configurations can be stabilized in the presence of destabilizing forces due to gravity or acoustic streaming flows.

Applicability and midterm results of branch cuff closure with vascular plug in branched endovascular repair for thoracoabdominal aortic aneurysms

Objective: This study assessed the applicability and outcomes of the closure of unused cuffs in branched endovascular aneurysm repair (b-EVAR) of thoracoabdominal aortic aneurysm. Methods: We reviewed b-EVAR procedures at a tertiary referral center to identify patients who underwent incomplete branching and needed closure of the unused branch cuffs. An electronic database and intraoperative and fo

Deformability-based sorting of red blood cells in deterministic lateral displacement devices

Mesoscopic simulations with two-dimensional (2D) models have been performed to elucidate the dynamics of deformable red blood cells (RBCs) in deterministic lateral displacement (DLD) devices. Several shapes of posts, including circular, diamond, square and triangular structures and RBCs with different rigidities are considered. In comparison to rigid particles, the deformable RBCs exhibit much mor

Early management of acute pancreatitis : A review of the best evidence

In the 20th century early management of acute pancreatitis often included surgical intervention, despite overwhelming mortality. The emergence of high-quality evidence (randomized controlled trials and meta-analyses) over the past two decades has notably shifted the treatment paradigm towards predominantly non-surgical management early in the course of acute pancreatitis. The present evidence-base

Swedish Feminist Foreign Policy in the Making : Ethics, Politics, and Gender

In 2015, the world's first self-defined feminist government was formed in Sweden with the explicit ambition of pursuing a feminist foreign policy. This essay seeks to unpack and highlight some of the substance and plausible future directions of a feminist foreign policy. The overarching ambition is three-fold: (1) to probe the normative contents of feminist foreign policy in theory and in practice

DNA sample cleanup using deterministic lateral displacement

Optical mapping relies on the preparation of fluorescent DNA. DNA must be imaged with good signal to noise and therefore the background of unwanted DNA fragments, fluorescent dyes and other reagents need to be removed. We use deterministic lateral displacement to separate 48.5 kbp DNA from < 10 kbp DNA. We also show the removal of 48.5 kbp DNA fragments from a background of fluorescent ATTO647N mo

An integrated acousto- and dielectrophoresis device for tumor cell separation, concentration, and single-cell trapping

Many microfluidic devices have been developed to separate rare cells, e.g. circulating tumor cells. The collection and analysis of the separated rare cells pose a challenge as it may lead to loss of target cells since extremely small number of cells are usually suspended in a large volume after separation. Here, we present an integrated device that allows acoustophoretic target cell separation and

Glycemia but not the Metabolic Syndrome is Associated with Cognitive Decline : Findings from the European Male Ageing Study

Objective: Previous research has indicated that components of the metabolic syndrome (MetS), such as hyperglycemia and hypertension, are negatively associated with cognition. However, evidence that MetS itself is related to cognitive performance has been inconsistent. This longitudinal study investigates whether MetS or its components affect cognitive decline in aging men and whether any interacti