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Asymtomatic Bacteriuria as a Model to Study the Coevolution of Hosts and Bacteria.

During asymptomatic bacteriuria (ABU), bacteria colonize the urinary tract for extended periods of time without causing symptoms of urinary tract infection. Previous studies indicate that many Escherichia coli (E. coli) strains that cause ABU have evolved from uropathogenic E. coli (UPEC) by reductive evolution and loss of the ability to express functional virulence factors. For instance, the prot

Salt-inducible kinase 1 influences Na+,K+-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure.

OBJECTIVES: Essential hypertension is a complex condition whose cause involves the interaction of multiple genetic and environmental factors such as salt intake. Salt-inducible kinase 1 (SIK1) is a sucrose-nonfermenting-like kinase isoform that belongs to the AMPK (5' adenosine monophosphate-activated protein kinase) family. SIK1 activity is increased by high salt intake and plays an essential rol

Levels of 1-hydroxypyrene, symptoms and immunologic markers in vulcanization workers in the southern Sweden rubber industries.

OBJECTIVES: The aim of this study was to determine urinary 1-hydroxypyrene (1-HP) levels in contemporary Swedish vulcanization workers and in controls. These levels were used as an index substance for vulcanization fumes, as well as a biomarker for polycyclic aromatic hydrocarbons (PAHs). The risk of symptoms and changed levels of immunologic markers were investigated in relation to the 1-HP level

Selected pregnancy variables in women with placental abruption

Objective: The aim of this study was to investigate risk factors for placental abruption and to determine if anamnestic variables such as inherited thrombosis or recurrent fetal loss might be used as a predictor for placental abruption. Methods: A retrospective case-control study at the University Hospital, Palacky University, Olomouc, Czech Republic. One hundred and eighty women with placental ab

The networked life of professional encyclopaedias: quantification, tradition, and trustworthiness

The article aims at making visible new orders of encyclopaedic knowledge by means of an ethnographic study carried out during eight months at the editorial office of the leading commercial encyclopaedia in Sweden, Nationalencyklopedin. The investigation is framed in a socio-technical understanding of how people, technologies and practices relate to each other. Three themes were identified during t

Antikoagulantia efter akut ischemisk stroke med förmaksflimmer - Frågan om rätt tidpunkt för insättning kräver randomiserad klinisk prövning.

Early or delayed onset of oral anticoagulant therapy in patients with acute ischemic stroke with atrial fibrillation is an unsolved issue. Retrospectively, 294 patient records at two hospitals were scrutinized according to a protocol consisting of 20 items regarding choice of therapy (warfarin or NOAC), time for onset of therapy, CT findings of bleeding, capacity to swallow, and occurrence of clin

On physical units in multivariate analysis

comparatively stringent mathematical frame has been developed, where the behaviour of physical dimensions (like ``length'', ``mass'', and ``time'') and physical units (like 1 m [1 metre], 1 kg [1 kilogramme], and 1 s [1 second]) is modelled. Easy-to-apply conditions for additivity and multiplicativity of physcial matrices are presented. Precise meanings of physically dimensional random variables,

RIFM fragrance ingredient safety assessment, ethyl anthranilate, CAS registry number 87-25-2.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC