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Nb3Cl8 : a prototypical layered Mott-Hubbard insulator

Despite its simplicity and relevance for the description of electronic correlations in solids, the Hubbard model is seldom inarguably realized in real materials. Here, we show that monolayer Nb3Cl8 is an ideal candidate to be described within a single-orbital Hubbard model, constructed within a “molecular” rather than atomic basis set using ab initio constrained random phase approximation calculat

Higher prevalence of coronary microvascular dysfunction in asymptomatic individuals with high levels of lipoprotein(a) with and without heterozygous familial hypercholesterolaemia

Background and aims: Microvascular dysfunction underlies many cardiovascular disease conditions; little is known regarding its presence in individuals with high levels of lipoprotein(a) [Lp(a)]. The aim of the present study was to determine the frequency of microvascular dysfunction among such subjects with and without concomitant familial hypercholesterolemia (FH). Methods: Four groups of asympto

Assessing topographic effects on forest responses to drought with multiple seasonal metrics from Sentinel-2

Topography determines run-off direction, redistributes groundwater, and affects land surface solar radiation loads and the associated evaporative forcing, consequently, topography can modulate the impact of drought and heat waves on ecosystems. This topographic modulation effect, which typically occurs at the local scale, is often overlooked when assessing ecosystem drought responses using moderat

Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome (BIO-MUSE) : Protocol for a Translational Study

BACKGROUND: Cutaneous T-cell lymphoma (CTCL) is a rare group of lymphomas that primarily affects the skin. Mycosis fungoides (MF) is the most common form of CTCL and Sézary syndrome (SS) is more infrequent. Early stages (IA-IIA) have a favorable prognosis, while advanced stages (IIB-IVB) have a worse prognosis. Around 25% of patients with early stages of the disease will progress to advanced stage

IMPLEMENTATION OF EVIDENCE-BASED INTERVENTIONS ACCORDING TO THE SWEDISH NATIONAL GUIDELINES FOR STROKECARE : A NATIONWIDE SURVEY AMONG PHYSIOTHERAPISTS

Objective: To investigate (i) to what extent physiotherapists (PTs) working in stroke rehabilitation in various parts of the stroke care chain have implemented interventions according to the national guidelines for stroke (NGS), (ii) facilita-ting and hindering factors for the implementation, and (iii) differences between various care settings. Design: A cross-sectional study. Subjects: 148 PTs wo

Ecological traits predict population trends of urban birds in Europe

The population dynamics of urban animals has been so far remarkably understudied. At the same time, urban species’ population trends can provide important information on the consequences of environmental changes in cities. We modelled long-term population trends of 93 bird species breeding in urban areas in 16 European countries as a function of species’ traits, characterising variability in their

Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells

Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a specific protein is a foundation of precision medicine and treatment. High expression of the proto-oncogene Bcl-3 promotes the proliferation and metastasis of cancer cells originating from tissues such as the colon, prostate, breast, and skin. The development of novel drugs targeting B

Nonadiabatic Charge Transfer within Photoexcited Nickel Porphyrins

Metalloporphyrins with open d-shell ions can drive biochemical energy cycles. However, their utilization in photoconversion is hampered by rapid deactivation. Mapping the relaxation pathways is essential for elaborating strategies that can favorably alter the charge dynamics through chemical design and photoexcitation conditions. Here, we combine transient optical absorption spectroscopy and trans

“Too Bad to Be True” : Swedish Economists on Keynes’s The Economic Consequences of the Peace and German Reparations, 1919–29

This chapter examines the response of five prominent Swedish economists, David Davidson, Gustav Cassel, Eli Heckscher, Knut Wicksell and Bertil Ohlin, to John Maynard Keynes’s The Economic Consequences of the Peace and to the German reparations in the 1920s. When Keynes’s book appeared, Davidson and Cassel strongly endorsed it. Heckscher also agreed with Keynes in a long review entitled “Too Bad t

Nationalekonomen: Sverige måste blicka mer västerut

”Än så länge finns inga tecken på att globaliseringen börjar gå baklänges. Den expanderar inte längre, men jag kan inte säga att vi är inne i en period av stark återgång ännu”, säger Fredrik N G Andersson.Han forskar om kriser och ekonomisk politik, och är docent i nationalekonomi vid Ekonomihögskolan vid Lunds universitet.

Mechanism-based therapy of non-cardiac syncope : a practical guide

The term non-cardiac syncope includes all forms of syncope, in which primary intrinsic cardiac mechanism and non-syncopal transient loss of consciousness can be ruled out. Reflex syncope and orthostatic hypotension are the most frequent etiologies of non-cardiac syncope. As no specific therapy is effective for all types of non-cardiac syncope, identifying the underlying hemodynamic mechanism is th

Evaluation of threshold-based models to account for surface moisture in meso-scale aeolian sediment transport simulations

Aeolian transport rates decreases during wet conditions as the threshold shear velocity for initiation of transport increases over moist sand. This study investigates the influence of surface moisture on meso-scale aeolian transport simulations. Yearly transport rates towards the dunes are simulated with ten different threshold-based models to account for moisture effects. The ten models show larg

Associations between daily home blood pressure measurements and self-reports of lifestyle and symptoms in primary care : the PERHIT study

OBJECTIVE: To explore in a primary care setting the associations between patients' daily self-measured blood pressure (BP) during eight weeks and concurrent self-reported values of wellbeing, lifestyle, symptoms, and medication intake. We also explore these associations for men and women separately.DESIGN AND SETTING: The study is a secondary post-hoc analysis of the randomised controlled trial PE

Den mjuka staten : Feminiseringen av samhället och dess konsekvenser

Under de senaste femtio åren har kvinnors makt i ­Sverige stärkts på ett dramatiskt sätt. Från att tidigare ha varit det generellt underordnade könet har kvinnor idag rentav en ­ledande ställning på många centrala områden. Viktiga yrken och samhälls­institutioner som tidigare dominerats av män domineras idag av kvinnor.I Den mjuka staten undersöker Erik J. Olsson och Catharina Grönqvist Olsson, ut

Longitudes, Syzygies, and Instruments in Regiomontanus' Calender for 1475-1531

Instruments and tables in Regiomontanus’ calendar published in 1474 are analysed and explained. It is shown that Regiomontanus used the Alfonsine Tables corrected for the longitude time difference between Toledo and Nuremberg. It is also shown that for the syzygy and eclipse times he used apparent solar times. The syzygy tables of George Peurbach may have been used to correct from mean to true syz

Four Instruments in Martín Cortés' Breve Compendio de la Sphera and a Rule for Finding the Age of the Moon

This paper investigates and discusses four instruments found in a sixteenth century Spanish book of navigation. The night clock is a rather standard application of similar instruments known since the fourteenth century in Europe. Cortés’ explanation of the causes of the deviation of the magnetic and geographical north is quite original. His instrument to correct for that the Polaris deviates from