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Emerging role of SOX11 in mantle cell lymphoma

During recent years the neural transcription factor SOX11 has been established as an important biomarker for mantle cell lymphoma. SOX11 is both a diagnostic and prognostic antigen, and may potentially be used for treatment selection for younger patients, in relation to protocols including high dose chemotherapy. The molecular pathways involved are still not fully elucidated and, as SOX11 can inte

Cultural Dissimilarity and Intermarriage. A Longitudinal Study of Immigrants in Sweden 1990-2005

Intermarriage with natives is a key indicator of immigrant integration. This article studies intermarriage for 138 immigrant groups in Sweden, using longitudinal individual level data. It shows great variation in marriage patterns across immigrant populations, ranging from over 70 percent endogamy in some immigrants groups to below 5 percent in other groups. Although part of this variation is expl

PCBaSe Sweden: A register-based resource for prostate cancer research

Objective. To construct a database for clinical epidemiological prostate cancer research based on linkages between the National Prostate Cancer Register (NPCR) of Sweden, a population-based, nationwide quality database, and other nationwide registries. Material and methods. By use of the individually unique Swedish Personal Identity Number, the NPCR was linked to the Swedish Cancer Registry, the C

Suppression of charged particle production at large transverse momentum in central Pb-Pb collisions at root s(NN)=2.76 TeV

Inclusive transverse momentum spectra of primary charged particles in Pb-Pb collisions at root s(NN) = 2.76 TeV have been measured by the ALICE Collaboration at the LHC. The data are presented for central and peripheral collisions, corresponding to 0-5% and 70-80% of the hadronic Pb-Pb cross section. The measured charged particle spectra in |eta| < 0.8 and 0.3 < p(T) < 20 GeV/c are compared to the

Sequential Monte Carlo Methods with Applications to Positioning and Tracking in Wireless Networks

This thesis is based on 5 papers exploring the filtering problem in non-linear non-Gaussian state-space models together with applications of Sequential Monte Carlo (also called particle filtering) methods to the positioning in wireless networks. The aim of the first paper is to study the performance of particle filtering techniques in mobile positioning using signal strength measurements. Two di

Auditory event-related potentials and cognitive outcome after very preterm birth

Popular Abstract in Swedish Barn födda före 32 gestationsveckor, även de utan svåra neurologiska avvikelser, har en hög förekomst av neuropsykologiska problem såsom läs-, inlärnings-, språk-, minnes- och beteendeproblem. Det är ännu inte klarlagt vilka funktionella och strukturella förändringar i hjärnan som orsakar dessa problem. Möjligheten till tidig diagnos behövs men saknas ännu. Auditiva hänChildren born before 32 gestational weeks have a high incidence of neuropsychological deficits. The structural and functional correlates of such impairments in preterm infants are incompletely understood, and early diagnostic tools are needed, but still lacking. Auditory event-related potentials (AERPs) are neurophysiological measures of cortical sound detection, encoding, discrimination, and atte

Lavar på den skotska västkusten

I samband med årets internationella mykologikongress IMC9 i Edinburgh anordnade IAL, International Association for Lichenology, en veckas lavexkursion på den skotska västkusten under ledning av Chris Ellis och Brian Coppins, den senare en av världens främsta lavexperter. Martin Westberg och Ulf Arup var med och skådade oceaniska rariteter.

A novel blood-based biomarker for detection of autism spectrum disorders.

Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/pep

Genetic Polymorphisms in Host Innate Immune Sensor Genes and the Risk of Nasopharyngeal Carcinoma in North Africa

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world. It is an Epstein-Barr virus-associated malignancy with an unusual racial and geographical distribution. The host innate immune sensor genes play an important role in infection recognition and immune response against viruses. Therefore, we examined the association between polymorphisms in genes within a group of pattern

Health-promoting educational interventions: A one-year follow-up study

Aims: The purpose of this study was to describe and analyse the effects of health-promoting educational interventions among employees in a municipality in Sweden. Methods: A randomized controlled educational intervention study was performed with 340 employees. Supervisors and workplace champions took part in two separate educational programmes with focus on health promotion. Intervention groups we

Patient-Specific Whole-Body Attenuation Correction Maps from a CT System for Conjugate-View-Based Activity Quantification: Method Development and Evaluation.

Abstract For activity quantification based on planar scintillation camera measurements, photon attenuation is an important factor that needs to be corrected for in a patient- and organ-specific manner. One possibility for obtaining attenuation correction maps is to use X-ray CT scout images. Since the intensity of scout images is in relative numbers, their image values need to be multiplied by a f

Genomic characterization of ETV6/RUNX1-positive acute lymphoblastic leukemia

The t(12;21) translocation generates the ETV6/RUNX1 fusion gene, present in 25% of childhood acute lymphoblastic leukemia. This fusion gene is important for leukemia development but is not sufficient for leukemia to arise. Hence, the additional genetic changes present in leukemic ETV6/RUNX1-positive cells give important clues regarding the history of the leukemia. The aim of this thesis has been t

Kursguidernas roll i högre utbildning : En studie av kursguidebruk vid Göteborgs universitet

Kursguider är en text som finns mellan kursplanens målformuleringar och själva genomförandet av en kurs. Den skrivs om för varje kurstillfälle för att anpassas till datum och specifika examinationsformer. Som undersökningsmaterial är kursguider därmed mycket praktiknära och ger mycket god insyn i hur undervisning är tänkt att ske. Trots detta har ingen tidigare forskning gjorts i Sverige kring det

Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Levels in Plasma of Suicide Attempters.

The soluble form of the urokinase receptor, suPAR, has been suggested as a novel biomarker of low-grade inflammation. Activation of the immune system has been proposed to contribute to the development of depression and suicidal behavior. In order to identify depressed and suicidal individuals who could benefit from an anti-inflammatory treatment, a reliable biomarker of low-grade inflammation is v

An Overview of the Latest Graphene-Based Sensors for Glucose Detection: the Effects of Graphene Defects

In this review, we analyze several types of graphene-based sensors for glucose detection with respect to their preparation, properties and efficiency in electro-chemical processes. Graphene may display different types of defects, which play a role in the electron transfer processes. Oxygenated groups on the edges of graphene planes reduce the graphene in-plane conductivity, but may enhance the het

An 0.8-mm(2) 9.6-mW Iterative Decoder for Faster-Than-Nyquist and Orthogonal Signaling Multicarrier Systems in 65-nm CMOS

This paper presents an iterative decoder for faster-than-Nyquist (FTN) and orthogonal signaling multi-carrier systems. FTN signaling is a method of improving bandwidth efficiency at the expense of higher processing complexity in the transceiver. The decoder can switch between orthogonal and FTN signaling modes and exploits channel properties to improve bandwidth efficiency. The decoder is fabricat

Glycemic Control and Cardiovascular Disease in 7,454 Patients With Type 1 Diabetes An observational study from the Swedish National Diabetes Register (NDR)

OBJECTIVE - We assessed the association between A1C and cardiovascular diseases (CVDs) in an observational study of patients with type 1 diabetes followed for 5 years. RESEARCH DESIGN AND METHODS - A total of 7,454 patients were studied from the Swedish National Diabetes Register (aged 20-65 years, diabetes duration 1-35 years, followed from 2002 to 2007). RESULTS - Hazard ratios (HRs) for fatal/n