Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra

Importance: Adjuvant imatinib is associated with improved recurrence-free survival (RFS) when administered after surgery to patients with operable gastrointestinal stromal tumor (GIST), but its influence on overall survival (OS) has remained uncertain. Objective: To evaluate the effect of adjuvant imatinib on OS of patients who have a high estimated risk for GIST recurrence after macroscopically c

AIMS/HYPOTHESIS: Psychological stress has long been considered a possible trigger of type 1 diabetes, although prospective studies examining the link between psychological stress or life events during pregnancy and the child's type 1 diabetes risk are rare. The objective of this study was to examine the association between life events during pregnancy and first-appearing islet autoantibodies (IA)

Importance: Aortic stenosis (AS) has no approved medical treatment. Identifying etiological pathways for AS could identify pharmacological targets. Objective: To identify novel genetic loci and pathways associated with AS. Design, Setting, and Participants: This genome-wide association study used a case-control design to evaluate 44703 participants (3469 cases of AS) of self-reported European ance

AbstractThe primary purpose of understanding disease etiology is to explain how a specific phenotype is determined by genotype. In pursue of this aim, exploring the diversity in DNA sequence variants that affect biomedical traits, especially those related to the onset and progression of genetically determined human disease. The human leukocyte antigens (HLA) are highly polymorphic cell surface pro

Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc

Background: 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the significance of CYP27A1 expression on BC biology and prognosis is unclear. Methods: Intratumoral CYP27A1 expression in invasive BC was measured by immunohistochemist

Although literature concerning chronic pain patients indicates that cognitive behavioural variables, specifically acceptance and fear of movement/(re)injury, are related to life impact, the relative roles of these factors in relation to pain characteristics (e.g. intensity and spreading) and emotional distress are unclear. Moreover, how these variables affect rehabilitation outcomes in different s

Background: Orthostatic hypotension (OH) is a major sign of cardiovascular autonomic failure leading to orthostatic intolerance and syncope. Orthostatic hypotension is traditionally divided into classical OH (cOH) and delayed OH (dOH), but the differences between the two variants are not well-studied. We performed a systematic clinical and neuroendocrine characterization of OH patients in a tertia

I svensk rätt råder fri bevisvärdering. Med fri bevisvärdering menas att domstolen inte är bunden av legala regler om viss metod eller visst tillvägagångssätt när denne värderar bevis. Endast ett fåtal hållpunkter till ledning för domstolen har satts upp i förarbeten, resten lämnas till rättstillämparen att fastställa. Vid bevisvärderingen använder sig domaren av allmänna erfarenhetssatser för att

Den här uppsatsen är ett examensarbete för juristprogrammet på Lunds universitet. Uppsatsen är skriven inom rättsområdet familjerätt och behandlar gällande rätt om vårdnadstvister samt problematiken kring uppgifter om våld i vårdnadstvister. Juridiska vårdnadstvister är ofta mycket känsliga och domstolen har många bestämmelser att förhålla sig till för att avgöra en tvist. Ytterligare en dimensioThis thesis is a degree project for the law program at Lund University. The essay is written within the juridical area of family law and deals with the established law on custody disputes and the problems regarding information about violence in custody disputes. Legal custody disputes are often quite sensitive and the court has to comply with several regulations when resolving a dispute. Moreover

Temperate freshwater shallow lakes are facing ecosystem level changes from climate change and biological invasions. Under IPCC’s future extreme warming scenarios, alien species that are introduced from lower latitudes could have a competitive advantage over the native species. This could instigate an irreversible impact on the biodiversity and ecosystem of these lakes. Therefore, scientific predic

Att värna om barn och barns rättigheter är frågor som ständigt är aktuella, och inom politiken framförs ständigt nya lagförslag på hur barnrättsperspektivet kan stärkas. I denna uppsats kommer därmed redogöras för om barns delaktighet i vårdnadstvister i den utsträckning som gällande rätt öppnar upp för är motiverad, samt om det är berättigat att stärka denna rätt. Uppsatsens syfte kommer uppnåsProtecting children and children's rights are issues that are constantly relevant, and in politics, new legislative proposals are constantly being put forward on how the child rights perspective can be strengthened. In this essay, it will be explained whether children's right to participation in custody disputes to the extent that applicable law opens up for today is motivated, and wheth

Digitaliseringen har lett till ett nytt marknadsföringslandskap där näringsidkare i allt större utsträckning använder sig av information om konsumenten för att skapa reklam på individnivå. Genom analys av olika typer av data som enskilda lämnar ifrån sig på den digitala och/eller fysiska marknaden kan företag identifiera potentiella konsumenter och målinrikta sin reklam. Det är till exempel möjligThe development of today’s digital world has led to a new marketing paradigm in which traders increasingly use information about consumers to create individually targeted advertisement. The consumer is monitored in both the digital and physical world of commerce. Different types of information about the consumer is collected and by analyzing this various data companies are able to identify potenti

To reduce the costs and survive the challenges of migration, animals should flexibly respond to changing environmental conditions along the route. In long-distance migratory birds, available habitat can vary substantially and so individual flexibility is needed to optimally exploit foraging opportunities, particularly for species that have specialized diets. However, flexible behavioral responses Seabirds adjust their behavior to migrate over changing landscapes Tracking birds with GPS technology, like the one that lets us consult Google Maps in our phones, has given exciting insight into how they are able to fly thousands of kilometers in challenging conditions over oceans and deserts during migration. Yet there are many species with fascinating migratory strategies that have not been tr

Barn i svenska förskolor utsätts för höga ljudnivåer som kan orsaka hörselskador och röstrelaterade problem bland både lärare och elever. Detta på grund av att de behöver höja rösten för att göra sig hörda i en bullrig miljö. På grund av detta är det av intresse att på något sätt kunna förutse ljudmiljön i just förskolor. Detta kan exempelvis göras genom att falta binaurala inspelningar av förskol

High Migratory and Cytotoxic Capability of CD56bright NK Cells in a Blood-Brain-Barrier in Vitro Model The blood brain barrier (BBB) is a tight structure in the Central Nervous System (CNS) that restricts the entry of immune cells. This restriction is regulated by different components such as endothelial cells, tight junction proteins and other cells such as pericytes, astrocytes and neurons. Nat

Huvudsyftet med denna framställning är att undersöka hur makars pensionsrättigheter behandlas vid en bodelning mellan makarna i anledning av äktenskapsskillnad. Fokus för uppsatsen är tjänstepension och privat pensionssparande. I syftet ingår att undersöka huruvida dagens reglering av makars pensionsrättigheter stämmer överens med likadelningsprincipen och principen om att var make svarar för sin The main purpose of this thesis is to examine how spouses' pension rights are treated in the event of a division of property between the spouses due to dissolution of the marriage. The focus of the thesis is the occupational pension and the private pension. The purpose further includes examining whether the current regulation of spouses' pension rights is in accordance with the principle o