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Changes in metabolites during an oral glucose tolerance test in early and mid-pregnancy : Findings from the PEARLS randomized, controlled lifestyle trial

The oral glucose tolerance test (OGTT) is used to diagnose gestational and other types of diabetes. We examined metabolite changes during an OGTT, and how a comprehensive diet and physical activity intervention may influence these changes in a population of overweight/obese Hispanic pregnant women. Integration of changes in metabolites during an OGTT may help us gain preliminary insights into how

Strategies for Companies in Supply Chains with turbulent environments

The borderless world is providing new opportunities for conducting business, both within Europe and between continents. Sustainable competition will be harder to attain and competition will become fiercer, day-by-day. The Austrian school of strategy emphasizes change, continuous innovation, and entrepreneurial discovery as sources of supernormal profits. An important assumption is that these super

A Probing Feeding Strategy for Recombinant E. coli Cultivations

*Summary: The bacterium Escherichia coli is a common host organism for recombinant protein production. A problem encountered is the accumulation of the by-product acetate, which tends to reduce growth and protein production (1). Formation of acetate can be avoided by a proper substrate feeding strategy, but most strategies require considerable process knowledge to work well. The main problem is th

Balancing health benefits and social sacrifices: A qualitative study of how screening-detected celiac disease impacts adolescents' quality of life

Background: Celiac disease often goes undiagnosed. Mass screening might be an option to reduce the public health burden of untreated celiac disease. However, mass screening is still controversial since it is uncertain whether the benefits of early detection outweigh the possible negative consequences. Before implementation of screening programs, the experiences of those being identified as cases s

Moisture Conditions and Frost Resistance of Concrete in Hydraulic Structures

Med avseende på de svenska förhållandena vintertid kan frostpåverkan antas ha betydande inverkan på nedbrytningen av betong i vattenbyggnader. Både ytliga och inre skador, vilka misstänks ha orsakats av frostpåverkan, har upptäckts på betong i exempelvis vattenkraftkonstruktioner. Nämnda observationer har väckt frågor om vattenbyggnaders beständighet i ett kallt klimat. Ytligt belägna skador, vil

Vertebral Scheuermann's disease in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over

The Summary In 27 centres across Europe, the prevalence of deforming spinal Scheuermann's disease in age-stratified population-based samples of over 10,000 men and women aged 50+ averaged 8 % in each sex, but was highly variable between centres. Low DXA BMD was un-associated with Scheuermann's, helping the differential diagnosis from osteoporosis. Introduction This study aims to assess the prevale

Parenthood and factors that influence outdoor recreational physical activity from a gender perspective

Background: A physically active life promotes both physical and mental health, increasing well-being and quality of life. Physical activity (PA) performed outdoors has been found to be particularly good for promoting well-being. However, participation in PA can change during the course of a lifetime. Parenthood has been found to be a life event associated with decreased PA, especially among women,

Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augment insulin response to glucose. It is less known what their effects are insulin clearance, which also contributes to peripheral hyperinsulinemia observed after administration of incretins together with glucose. The aims of this study were the quantification of C-peptide secretion and the evaluation

Walking in old age: A year-round perspective on accessibility in the outdoor environment and effects of measures taken

Accessibility throughout society has been gaining interest on both international and national levels in order to meet the transportation needs of, for example, older people as pedestrians. The overall aim of this thesis is to examine the implementation process in municipal planning, and effects of measures taken, to achieve barrier-free outdoor environments the year round. Older peoples’ perceptio

Depression, smoking, physical inactivity and season independently associated with midnight salivary cortisol in type 1 diabetes

BACKGROUND: Disturbances of the circadian rhythm of cortisol secretion are associated with depression, coronary calcification, and higher all-cause and cardiovascular mortality.The primary aim of this study was to test the associations between midnight salivary cortisol (MSC), depression and HbA1c, and control for behavioural, environmental and intra individual factors with possible impact on cort

Online Piracy, Anonymity and Social Change – Deviance Through Innovation

This article analyses current trends in the use of anonymity services among younger Swedes (15-25) and focuses on individuals engaging in illegal file sharing in order to better understand the rationale behind both file sharing as well as online anonymity, especially in relation to enforcement of copyright. By comparing the findings of a survey conducted on three different occasions (early 2009, l

Job satisfaction, strain and stress of conscience among nurse assistants working in residential care for older people

The overall aim of the thesis was to investigate and explore job satisfaction, strain and stress of conscience (SC) among nurse assistants (NAs) working in residential care for older people. The thesis had a descriptive, cross-sectional and correlational design and consisted of one paper where qualitative methodology was used and three where quantitative methodology was used. The qualitative study

Universiteten och kompetenslandskapet : Effekter av den högre utbildningens tillväxt och regionala spridning i Sverige

Popular AbstractI Sverige har utbildningspolitiken under de senaste decennierna fått en viktig roll i att främja målsättningar också inom en rad andra politikområden, bland annat det regionalpolitiska. Högskolorna skall bidra till att utjämna sociala och ekonomiska skillnader mellan olika grupper i befolkningen, stimulera innovationsförmågan i näringslivet och generera nya företag. Undersökningarn

Genetics of diabetes - Are we missing the genes or the disease?

Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Several pathogenic processes are involved in the development of diabetes