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Background: Predicting future risk for oral diseases, treatment need and prognosis are tasks performed daily in clinical practice. A large variety of methods have been reported, ranging from clinical judgement or "gut feeling" or even patient interviewing, to complex assessments of combinations of known risk factors. In clinical practice, there is an ongoing continuous search for less complicated
Introduction: Epidemiological research methods have been shown to be useful in determining factors that might predict commonly reported negative public attitudes toward stuttering. Previous research has suggested that stuttering attitudes of respondents from North America and Europe (i.e., "The West"), though characterized by stereotypes and potential stigma, are more positive than those from seve
Background-Diabetes mellitus (DM) and cardiovascular disease are associated with dyslipidemia, but the detailed lipid molecular pattern in both diseases remains unknown. Methods and Results-We used shotgun mass spectrometry to determine serum levels of 255 molecular lipids in 316 controls, 171 DM, and 99 myocardial infarction (MI) events from a cohort derived from the Malmö Diet and Cancer study.
Background: Atrial fibrillation (AF) detection in ischemic stroke patients triggers initiation of oral anticoagulant therapy (OAC). However, little is known regarding whether the persistency of AF affects long-term prognosis after ischemic stroke. We aimed to assess the impact of AF types and OAC on the outcome during a 10-year follow-up (FU) after first-ever ischemic stroke. Material and methods:
Svensk sammanfattningUnder de senaste hundra åren har kulturlandskapet i norra Europa genomgått en dramatisk förändring. Det småskaliga jordbrukslandskapet med sin mosaik av naturtyper har till stor del ersatts av vidsträckta monokulturer. Artrika naturtyper och naturområden har blivit ovanligare och ligger idag ofta isolerats från varandra. Som en följd av detta har många arter gått tillbaka, visPlant species often adapt to local environmental conditions, which can result in the formation of genetically and phenotypically distinct ecotypes. Ecotypes can evolve rapidly, and may be a first step in the process of ecological speciation. Consequently, ecotypes may constitute an important part of the biodiversity in regions with a young flora, where few endemic taxa at the species level have ha
Internet Metaphors and Norms To what extent is digital “openness” also creating a modern “Panopticon”? I.e. to what extent is the conceptual imaginary of relevance for the legitimacy of modern data practices in terms of privacy? This paper argues that conceptual battles around what the Internet is and the digital development means are significant battles. The metaphorical descriptions of the inteInternet Metaphors and Norms. To what extent is digital “openness” also creating a modern “Panopticon”? I.e. to what extent is the conceptual imaginary of relevance for the legitimacy of modern data practices in terms of privacy? This paper argues that conceptual battles around what the Internet is and the digital development means are significant battles. The metaphorical descriptions of the inte
Aims/hypothesis To develop a prediction model that can predict HbA1c levels after six years in the non-diabetic general population, including previously used readily available predictors. Methods Data from 5,762 initially non-diabetic subjects from three population-based cohorts (Hoorn Study, Inter99, KORA S4/F4) were combined to predict HbA1c levels at six year follow-up. Using backward selection
PURPOSE: Welders are exposed to airborne particles from the welding environment and often develop symptoms work-related from the airways. A large fraction of the particles from welding are in the nano-size range. In this study we investigate if the welders' airways are affected by exposure to particles derived from gas metal arc welding in mild steel in levels corresponding to a normal welding day
Purpose: Germline mutations in tumour suppressor genes cause various cancers. These genes are also somatically mutated in sporadic tumours. We hypothesized that there may also be cancer-related germline variants in the genes commonly mutated in sporadic breast tumours. Methods: After excluding the well-characterized breast cancer (BC) genes, we screened 15 novel genes consistently classified as BC
Multifunctional agriculture provides noncommodity functions and services along with food, feed and bioenergy feedstocks, for example by preserving or promoting biodiversity, improving soil fertility, mitigating climate change and environmental degradation, and contributing to the socio-economic viability of rural areas. Producing biomass for bioenergy from low-input perennial species mixtures on m
Obesity and its associated comorbidities (for example, diabetes mellitus and hepatic steatosis) contribute to approximately 2.5 million deaths annually and are among the most prevalent and challenging conditions confronting the medical profession. Neurotensin (NT; also known as NTS), a 13-amino-acid peptide predominantly localized in specialized enteroendocrine cells of the small intestine and rel
Disease prevalence in wildlife is governed by epidemiological parameters (infection and recovery rates) and response to infection, both of which vary within and among individual hosts. Studies quantifying these individual-scale parameters and documenting their source of variation in wild hosts are fundamental for predicting disease dynamics. Such studies do not exist for the influenza A virus (IAV
OBJECTIVE: To assess the effect of the FTO genotype on weight loss after dietary, physical activity, or drug based interventions in randomised controlled trials.DESIGN: Systematic review and random effects meta-analysis of individual participant data from randomised controlled trials.DATA SOURCES: Ovid Medline, Scopus, Embase, and Cochrane from inception to November 2015.ELIGIBILITY CRITERIA FO
oxLDL peptide vaccine and its antibody adoptive transferring have shown a significantly preventive or therapeutic effect in atherosclerotic animal model. The molecular mechanism behind this is obscure. Here, we report that oxLDL induces MCP-1 release in monocytes/macrophages through their TLR-4 (Toll-like receptor 4) and ERK MAPK pathway and is calcium/potassium channel-dependent. Using blocking a
