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Studying gene-lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting important subgroup effects. Adequately powered studies with prospective, unbiased, standardised assessment of key behavioural factors for gene-lifestyle studies are lacking. This case-cohort study aims to investigate how genetic and potentially modifiable
A large number of studies have shown that friends’ smoking behavior is strongly associated with an individual’s own risk for smoking. However, few studies have examined whether other features of social networks, independently or conjointly with friends’ smoking behavior, may influence the risk for smoking. Because it is characterized by the growing importance of friendship networks, the transition
Unique measurements of vertical size-resolved aerosol particle concentrations, trace gas concentrations and meteorological data were obtained during the Arctic Summer Cloud Ocean Study (ASCOS, www.ascos.se), an International Polar Year project aimed at establishing the processes responsible for formation and evolution of low-level clouds over the high Arctic summer pack ice. The experiment was con
For the first time in Europe, both European-wide and country-specific levels of urinary Bisphenol A (BPA) were obtained through a harmonized protocol for participant recruitment, sampling and quality controlled biomarker analysis in the frame of the twin projects COPHES and DEMOCOPHES. 674 child-mother pairs were recruited through schools or population registers from six European member states (Be
Shelf and coastal regions are exceptionally important for many countries as they provide the main habitat for many economically important fish and shellfish species. With ongoing climate change and human-induced eutrophication the shelf regions are especially affected, resulting in increased temperatures and stratification as well as oxygen depletion of the bottom waters. In order to be able to pr
Study Type - Prognosis inception (cohort) Level of Evidence 2 What's known on the subject? and What does the study add? There are two randomized controlled trials showing that radiotherapy can be beneficial for men with locally advanced prostate cancer. The present study confirms the importance of curative treatment for men with high-risk prostate cancer. OBJECTIVE: • To investigate the influen
Background: The association between adiposity and cardiometabolic traits is well known from epidemiological studies. Whilst the causal relationship is clear for some of these traits, for others it is not. We aimed to determine whether adiposity is causally related to various cardiometabolic traits using the Mendelian randomization approach. Methods and Findings: We used the adiposity-associated va
1. Temperate semi-natural grasslands are characterized by high levels of species diversity and have a high conservation value. Plant species diversity in grazed semi-natural grasslands is known to be influenced by management intensity and habitat connectivity. Both grazing pressure and between-patch connectivity are expected to depend on the movement patterns of livestock in the landscape. 2. The
Background: The recently established international cystatin C calibrator makes it possible to develop non-laboratory specific glomerular filtration rate (GFR) estimating (eGFR) equations. This study compares the performance of the arithmetic mean of the revised Lund-Malmo creatinine and CAPA cystatin C equations (MEAN(LM-REV+CAPA)), the arithmetic mean of the Chronic Kidney Disease Epidemiology Co
Popular AbstractVad vet vi egentligen om maten vi äter? Vem producerar den och var kommer den ifrån? Hur vet vi att vi inte blir sjuka av den? Är svenskt kött bättre än annat kött? Varför väljer en del konsumenter att handla mat i gårdsbutiker eller på grönsaksmarknader istället för i butik? Frågorna kring maten är många. Avståndet mellan producent och konsument är idag stort och innan råvaran harThis dissertation takes up the consequences of the transition from a traditional to a modern food system. According to some researchers, the modernization of food production has led to a crisis of confidence in today’s food system and consumers are said to experience alienation, gastro-anomie, and distrust towards food products (see Murcott, Mennell & Van Otterloo 1992; Fischler 1980; 1988). P
Objectives: To assess the risk of lymphoproliferative disease or other malignancy (standardised incidence ratios (SIRs)), in patients with primary Sjogren's syndrome according to the American-European Consensus Criteria (AECC), compared with patients with sicca syndrome (non-AECC) and the background population. To identify predictors of malignancy and describe lymphoma types and survival probabili
Objective. Helicobacter pylori infection is an established risk factor for non-cardia gastric adenocarcinoma. Infection with H. pylori strains harbouring the cagA pathology island may augment this association. H. pylori infection may at the same time reduce the risk for oesophageal carcinoma. However, prospective data on the association between CagA seropositivity and gastric or oesophageal carcin
Much of earlier work on predictive models for accidents has been focused on rural traffic or urban intersections. This work has aimed at identifying and investigating possible improvements to predictive models for accidents on urban links. A special focus has been on the accidents of vulnerable road users. The possible improvements investigated have been: a) the use of exposure data for vulnerabl
Scolecodonts, polychaete jaws, generally occur abundantly in Silurian shallow marine successions and are known from all continents except Antarctica. The assemblages are typically characterized by taxa with labidognath, placognath and prionognath type jaw apparatuses. They commonly include species of Kettnerites Zebera, 1935, Oenonites Hinde, 1879, Mochtyella Kielan-Jaworowska, 1961, Protarabellit
The overall aim was to investigate chronic pain, quality of life and factors associated with pain as well as with quality of life among older people, aged 75 years and above. Further, the aim was to investigate the use of methods for pain management and their effects for those with pain and in need of help for daily living. Data were collected from a larger population study and in the first study
Catchment-scale material transport models are today important tools for water and environmental management. However, modelling of material transport is extremely complex due to the physical, chemical and biological processes involved. The complexity calls for spatial distribution and thereby a need for large amounts of input data that generally are not available. Lumped models based on conceptual
