The osteopontin-derived peptide FOL-005 stimulates hair growth. Using ligand-receptor glyco-capture technology we identified neuropilin-1 (NRP-1), a known co-receptor for vascular endothelial growth factor (VEGF) receptors, as the most probable receptor for FOL-005 and the more stable analogue FOL-026. X-ray diffraction and microscale thermophoresis analysis revealed that FOL-026 shares binding si

The transition of heavy machinery systems in agriculture is becoming increasingly urgent due to evolving regulations, market volatility in fossil fuels, and the imperative to achieve decarbonization objectives in the sector. Agricultural machinery has recently experienced an increase in automation, resulting in a higher implementation of electric actuators and systems in agricultural machinery. Th

OBJECTIVE: To investigate the relationship between the fraction of fetal haemoglobin (HbF(%)) and oxygen requirement as determined by the fraction of inspired oxygen (FiO2) and alveolar-arterial gradient (A-a gradient). Increased alveolar exposure to oxygen may explain the association between decreased HbF(%) and the development of bronchopulmonary dysplasia (BPD).DESIGN: Longitudinal, retrospecti

Increasing iron (Fe) concentrations are found in lakes on a wide geographical scale but exact causes are still debated. The observed trends might result from increased Fe loading from the terrestrial catchment, but also from changes in how Fe distributes between the water column and the sediments. To get a better understanding of the causes we investigated whether there has been any change in the

To investigate whether coronary artery disease (CAD) burden is associated with plasma levels of the myocardial biomarkers Troponin I (TropI) and NT-proBNP in a large population-based sample using a cross-sectional design. Coronary computerized tomography (CT) angiography was performed in 25,859 subjects without a history of atherosclerotic disease from SCAPIS study (age 50-65, 52% women). TropI an

PURPOSEOur aim was to assess the impact of cigarette smoking on the risk of the tumors classified by the International Agency for Research on Cancer as causally associated with smoking, referred to as tobacco-related cancers (TRC). METHODSThe study population included 441,211 participants (133,018 men and 308,193 women) from the European Prospective Investigation Into Cancer and Nutrition. We inve

BACKGROUND: To evaluate factors associated with incidence and 3-year all-cause mortality in patients with aortic aneurysm (AA). The design is sex and age-stratified (60-79 and 80-90 years) prospective cohort. By using the population register, we constituted a cohort of all men and women born between 1900 and 1930 and living in Scania by 1991, and followed them for 13 years. Identification of AA wa

Barnets bästa ska vara avgörande vid alla beslut som rör vårdnad, boende och umgänge. Vid bedömningen av barnets bästa skall hänsyn tas till barnets vilja med beaktande av barnets ålder och mognad. Det framgår tydligt av såväl FN:s konvention om barnets rättigheter (barnkonventionen) och av svensk lag. Lagtexten ger endast vägledande riktlinjer när det gäller bedömningen av barnets bästa för att uThe best interest of the child should always be decisive in all decisions concerning custody, accommodation, and relations of the child. When assessing what is best for the child the will of the child should be considered. Moreover, the will of the child should be evaluated according to two affecting factors; age and maturity. This clearly appears in the Convention on the Rights of the Child prese

Identifierade orsaker och åtgärder för att minska matsvinn inom gymnasieskolor Livsmedel som slutar som matsvinn bidrar till den negativa miljöpåverkningar som bland annat ökad växthuseffekt, övergödning och utnyttjande av naturresurser. Matsvinn är ett stort problem inom många områden. Skolor är det den sektorn inom storkök som bidrar till mest matsvinn årligen. I svenska skolor kastas det i sn

Markslitage i fjällmiljö Ett ökat intresse för fjällturism leder till markslitage i fällen. Fjällmiljön har en lång återhämtningstid och därför måste åtgärder sättas in i god tid för att kunna bibehålla en storslagen fjällmiljö. Genom att studera området Södra Årefjällen, genom framställning i media och genom en dokumentsökning, har en kartläggning gjorts på hur olika aktiviteter påverkar markmilj

Beräkningsmodeller för konsumtionsbaserade utsläpp, vad är vitsen? Julia Nordström i juni 2018 År 2015 skrev Sverige tillsammans med andra nationer under det internationella klimatavtalet - Parisavtalet. För att nå de mål som Parisavtalet satt upp måste de globala utsläppen av växthusgaser minska drastiskt de kommande åren. Sverige är ett av de mest framstående länderna i världen när det kommer tIn recent years, it has become increasingly recognized that the traditional production-based methods for calculations of greenhouse gas emissions have shortcomings. This is justified by the fact that such inventories only include emissions that occur within a particular geographical area. As major emissions also arise as a result of imports of goods and services and from international travel, such