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Cardiac biomarkers for detection of coronary artery disease in the community

To investigate whether coronary artery disease (CAD) burden is associated with plasma levels of the myocardial biomarkers Troponin I (TropI) and NT-proBNP in a large population-based sample using a cross-sectional design. Coronary computerized tomography (CT) angiography was performed in 25,859 subjects without a history of atherosclerotic disease from SCAPIS study (age 50-65, 52% women). TropI an

Association Between the EAT-Lancet Reference Diet and Gestational Diabetes Mellitus : A Mini-Review

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication that seriously endangers maternal and infant health, posing a medical and economic burden worldwide. Several dietary patterns have been recommended for women of childbearing age, demonstrating a positive role in preventing and managing GDM. However, these dietary patterns may not fully take environmental factors into account

Fragmentation in Collisions of Snow with Graupel/Hail : New Formulation from Field Observations

Secondary ice production (SIP) has been attributed to the generation of most ice particles observed in precipitating clouds with cloud tops warmer than 2368C, from various aircraft- and ground-based field observations across the globe. One of the known SIP mechanisms is fragmentation during collisions among ice particles. It has been studied with our theoretical formulation, which has been applied

Artificial Emotional Intelligence: AI perspectives on emotional transmediation in contemporary science-fiction opera

This paper investigates the confluence of artificial intelligence (AI), the performing arts, and emotion communication, focusing on how generative AI and social robotics – today’s forefront disruptive technologies – can facilitate an exploration of emotional dynamics across artistic mediums. Drawing on the intermedial and multimodal capacities of opera, this paper presents AI-enhanced opera as a p

Infective endocarditis caused by non-HACEK Gram-negative bacteria, a registry-based comparative study

Introduction/objectivesInfective endocarditis (IE) caused by non-HACEK Gram-negative bacteria (nHGNB) is uncommon. In the 2023 Duke-ISCVID diagnostic criteria, Pseudomonas aeruginosa and Serratia marcescens were added as “typical” pathogens. We examine the consequences of this addition, the risk of IE in bacteremia from nHGNB species and the features of IE caused by nHGNB.Materials and methodsnHGN

Fasting glucose, bone area and bone mineral density: A Mendelian randomisation study.

Aims/hypothesisObservational studies indicate that type 2 diabetes mellitus and fasting glucose levels are associated with a greater risk for hip fracture, smaller bone area and higher bone mineral density (BMD). However, these findings may be biased by residual confounding and reverse causation. Mendelian randomisation (MR) utilises genetic variants as instruments for exposures in an attempt to a

Presenting Counterpoints to the Dominant Terrestrial Narrative of European Prehistory

Challenges the terrestrial focus of European prehistory, emphasizing the significance of seascapes, maritime networks, and coastal societies in shaping prehistoric Europe.For many years now, the main thrust of European prehistory has followed a fundamentally terrestrial plot line. This terrestrial paradigm has undervalued the story of Europe as a peninsula between the Baltic, Mediterranean and Atl

In the Mood for Likes : A Longitudinal Study of Civil Society Organizations’ Emotional Communication on Social Media

Emotional communication, especially through social media platforms, has become a contemporary populist threat. While this phenomenon has been studied in for example news media and social movements, we know less about its influence on civil society organizations, despite their pluralism being a centerpiece in a vibrant democracy. More specifically, we do not know if social media make civil society

Who is at risk of long-term subjective memory impairment after electroconvulsive therapy?

Background: Electroconvulsive therapy (ECT) is an effective treatment for depression with potential transient cognitive side effects. However, subjective memory impairment can extend over a long period after ECT. Objectives: This study aimed to assess potential risk factors for long-term subjective memory impairment 6 months after ECT and to explore if the associations are mediated by depressive s

Long term inguinal pain comparing TEP to Lichtenstein repair : the TEPLICH RCT 8 years follow-up

Purpose: To investigate long-term chronic postoperative inguinal pain (CPIP), QoL and recurrence in patients with a primary inguinal hernia comparing TEP to Lichtenstein. Material and methods: A questionnaire-based follow-up containing the Inguinal Pain Questionnaire (IPQ), the Cunningham Pain Scale and SF-36 was done 8 years after the TEPLICH RCT. The main objective was non-ignorable pain last we

Impact of maternal prepregnancy body mass index on neonatal outcomes following extremely preterm birth

Objective: Extremes of prepregnancy maternal BMI increase neonatal mortality and morbidity at term. They also increase the risk of extremely preterm (EP, i.e., <27 weeks' gestational age) births. However, the association between maternal BMI and outcomes for EP babies is poorly understood. Methods: We used a cross-country design, bringing together the following three population-based, prospective,

Association between clinical outcome and microbiological findings in peritonsillar abscess - an observational study

Background: Previous studies on causative pathogens in peritonsillar abscesses have yielded varying results. However, Group A streptococci (GAS) and Fusobacterium necrophorum have been identified frequently. The aim of this study was to investigate pathogens in peritonsillar abscesses in patients tested for both ß-hemolytic streptococci and F. necrophorum, and to investigate associations between p

A novel nature-based intervention rehabilitation program including equine-assisted therapy (the NBI-RP) for people with severe stress-related mental health problems. Outcomes on health, personal recovery, and activity level.

Objective: Stress-related mental health problems (MHP) are increasing worldwide. It has been shown that people with stress-related MHP may benefit from nature-based interventions (NBI), and equine-assisted therapy (EAT) to support their health, recovery, and activity level of daily life. However, the evidence-base to support this is still weak and there is a knowledge gap concerning health-, recov

Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology

The genetics of β-cell function (BCF) offer valuable insights into the aetiology of type 2 diabetes (T2D)1,2. Previous studies have expanded the catalogue of BCF genetic associations through candidate gene studies3–7, large-scale genome-wide association studies (GWAS) of fasting BCF8,9 or functional islet studies on T2D risk variants10–14. Nonetheless, GWAS focused on BCF traits derived from oral

Inborn errors of immunity are associated with increased COVID-19–related hospitalization and intensive care compared to the general population

Background: It is thought that patients with inborn errors of immunity (IEI) are more susceptible to severe coronavirus disease 2019 (COVID-19) than the general population, but a quantification of this potential risk is largely missing. Objective: We assessed the impact of COVID-19 on patients with IEI. Methods: A nationwide cohort study was performed to estimate the relative risk (RR) for hospita

24-hour Urine Calcium Predicts Reduced Fracture Incidence and Improved Bone Mineral Density After Surgery for Primary Hyperparathyroidism

Context: Contemporary patients with primary hyperparathyroidism are diagnosed with milder disease than previously. Clinical and biochemical factors predictors with an impact on fracture incidence and bone mineral density after surgery have not been firmly established. Objective: To investigate predictors of fracture incidence and bone mineral density preoperatively and after surgery for primary hy

Butyrate-producing bacteria as probiotic supplement : beneficial effects on metabolism and modulation of behaviour in an obesity mouse model

Obesity is a risk factor for cardio-metabolic and neurological disease. The contribution of gut microbiota to derangements of the gut-brain axis in the context of obesity has been acknowledged, particularly through physiology modulation by short-chain fatty acids (SCFAs). Thus, probiotic interventions and administration of SCFAs have been employed with the purpose of alleviating symptoms in both m