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Quality of life among female childhood cancer survivors with and without premature ovarian insufficiency

Purpose: Due to an increase in survival, a growing population of childhood cancer survivors (CCS) is present. However, female CCS are at risk of developing premature ovarian insufficiency (POI) after cancer treatment. POI involves a decreased chance of conceiving and the increased infertility state has a large impact on affected individuals’ health and mental life. The objective of this study was

Automated artificial intelligence-based analysis of skeletal muscle volume predicts overall survival after cystectomy for urinary bladder cancer

Background: Radical cystectomy for urinary bladder cancer is a procedure associated with a high risk of complications, and poor overall survival (OS) due to both patient and tumour factors. Sarcopenia is one such patient factor. We have developed a fully automated artificial intelligence (AI)-based image analysis tool for segmenting skeletal muscle of the torso and calculating the muscle volume. M

Extreme-resolution synchrotron X-Ray fluorescence mapping of ore samples

In order to maximise profit and sustainability of a mining operation, knowledge of the chemistry, mineralogy, texture, and structure of the ore is essential. Continuous advancements in analytical techniques enable studying these features with increasing detail. Synchrotron radiation X-ray fluorescence is unparalleled in its simultaneously high spatial resolution and detection range. Yet, its appli

Empirical Studies on Firm and Labor Market Dynamics

This thesis consists of three self-contained papers. The first paper, Sorting on Unobserved Skills into New Firms, adds to the literature on worker characteristics and post-entry firm performance by putting the unobserved quality of workers in the center of analysis. Although human capital features prominently in theoretical work on the post-entry performance of new firms, empirical analysis has l

Anorexia nervosa and autism : a prospective twin cohort study

Background: Anorexia nervosa (AN) and autism spectrum disorder (ASD) may be phenotypically and etiologically linked. However, due to the absence of prospective studies, it remains unclear whether the elevation of autistic traits in AN is evident in early childhood. Here, we prospectively investigated autistic traits before and after the first diagnosis of AN. Methods: In a population-based sample

Socioeconomic status and alcohol use disorders across the lifespan : A co-relative control study

OBJECTIVES: Alcohol use disorders (AUD) is well known to aggregate in families and is associated with socioeconomic status (SES). The objective was to study the effect of education, income and neighborhood SES in adulthood on AUD, and to explore whether the potential associations were confounded by shared familial factors, by using a co-relative control design. METHODS: Data on AUD was drawn from