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Polyglandular Autoimmune (PGA) syndrome type II in idiopathic Addison's disease: In a retrospective study of idiopathic Ad-dison's disease (median age at diagnosis 32.5 years, range 8-62; median observation time 17 years, range 0.5-41), 50% met the criteria for PGA syndrome type II. In PGA syndrome type II, 73% had ATD and 41% had IDDM. The full triad was present in 14%. The sequence of appearance
Biomedical research projects involving multiple partners from public and private sectors require coherent internal governance mechanisms to engender good working relationships. The DIRECT project is an example of such a venture, funded by the Innovative Medicines Initiative Joint Undertaking (IMI JU). This paper describes the data access policy that was developed within DIRECT to support data acce
Paying privately for childcare is a growing phenomenon, and its rise in Sweden is particularly interesting because of the vast prevalence there of publicly funded day care. This book combines family practice and childhood studies theory with the personal perspectives of nannies and au pairs, parents, and the children themselves, to provide new understandings of what constitutes ‘good care’. The au
Background: Long-term insulin exposure has been implicated in breast cancer etiology, but epidemiological evidence remains inconclusive. The aims of this study were to investigate the association of insulin therapy with mammographic density (MD) as an intermediate phenotype for breast cancer and to assess associations with long-term elevated circulating insulin levels using a genetic score compris
Abstract: Cardiovascular diseases and diabetes mellitus are closely linked by sharing common risk factors, such as obesity, insulin resistance, hypertension and dyslipidaemia. These intermediate risk factors are affected by the joint effects of environment and genetics. Although a multitude of studies aimed to disentangle the effects of gene-environment interactions, many of the published gene-en
BACKGROUND: Cardiac rehabilitation (CR) programs addressing risk factor management, educational interventions, and exercise contribute to reduce mortality after myocardial infarction (MI). However, the fulfillment of guideline-recommended CR targets is currently unsatisfactory. eHealth, i.e., the use of electronic communication for healthcare, including the use of mobile smartphone applications co
The article focuses on a current trend in office design: Activity Based Work (ABW). This is an office solution that instead of providing employees with designated places, it provides them with a variety of spaces in the office that offer different functionalities. A case study is presented of the ongoing effort of a multinational technology company in the software industry to implement ABW at a lo
Background: In the DETO2X-AMI trial (Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction), we compared supplemental oxygen with ambient air in normoxemic patients presenting with suspected myocardial infarction and found no significant survival benefit at 1 year. However, important secondary end points were not yet available. We now report the prespecified secondary end po
Introduction In an age when brands have seized the imagination of so many, the corporate landscape has become a brandscape. Recently, corporate branding has emerged as an important agenda item for many senior executives. Brands are viewed as a significant corporate asset. The corporate brand is viewed as an important profile builder for corporations. It is seen as an invaluable tool for attracting
An overview of optical techniques for environmental monitoring is presented. Range-resolved measurements of atmospheric pollutants can be performed using the differential absorption lidar technique. Fluorescence lidar allows assessment of vegetation status and also the conditions of the facades of historical buildings. Diode lasers provide particularly realistic schemes for atmospheric gas analysi
The aim of this study was to delineate management zones by using topographical data, and to investigate how these management zones relate to soil parameters and yield. Elevation, as well as soil and yield data, were sampled in the field. Digital elevation models have been created, and the topographical parameters of slope, aspect and drainage area, estimated. Management zones have been delineated
Background: Despite the compelling scientific evidence on the superiority of stroke unit care, far from all acute stroke patients have access to stroke unit care. In congruence with what has been observed when other new methods are introduced in health care, we hypothesized that there has been an inequality in the buildup phase of stroke units but that the gradients between patient groups have dec
