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Context Substantial diagnostic delay in acromegaly contributes to increased morbidity and mortality. Screening attempts in high-risk groups have yielded few positive cases, underscoring the need for simple and precise prescreening methods. Objective Machine-learning analysis of facial images shows promise for acromegaly detection but requires validation in larger, well-characterized cohorts using
In this study we investigate day-care centres as a form of community-based support designed to facilitate ageing in place for individuals with dementia, with the goal of delaying or preventing their transition to institutional care. Day-care centres provide structured activities designed to alleviate loneliness and isolation, affirm personal identity, and offer respite for family caregivers. In Sw
Background: Parkinson's disease and atypical parkinsonism are characterized by motor and non-motor symptoms. As the disease advances, planning for end-of-life (EoL) care becomes increasingly important. However, consensus-based European guidelines for advance care planning and documentation of EoL care preferences for parkinsonism are lacking. Understanding current documentation practices for EoL c
Conventional capacity expansion planning (CEP) relies on a perfect-foresight planning horizon and linear investment optimisation, which fail to capture the non-linear dynamics of electricity markets. In the Nordics, hydro-related weather variability plays a critical role in maintaining the robustness of the power system. This paper addresses the intra-year perfect-foresight limitation in current C
AIMS: A history of preeclampsia is associated with at least a twofold increased risk of coronary artery disease (CAD), with unclear underlying mechanisms. This study aimed to investigate coronary plaque characteristics in women with a history of preeclampsia compared to women from the general population.METHODS: In this cross-sectional study, women with a history of preeclampsia from the Cardiovas
The aim of this dissertation is to map out and illustrate particularly troublesome and central areas in grammar learning. The point of departure is Josefsson and Lundin’s three suggested threshold concepts within grammar: to be able to distinguish between meaning, form and function, to be able to distinguish between a linear and a hierarchical dimension and to be able to identify and segment claus
Background: Bile leakage is a severe complication after cholecystectomy and is associated with an increased risk of morbidity and mortality. The aim of this study was to evaluate the incidence of bile leakage post-cholecystectomy and to identify potential risk factors and their association with changes in the incidence of bile leakage over time. Methods: Demographic and perioperative data of all p
Background: The use of high-flow oxygen therapy (HFOT) compared with standard low-flow oxygen therapy (LFOT) may improve outcomes in people with oxygen-dependent chronic respiratory failure (CRF). The primary aim of this multicentre trial was to evaluate HFOT in addition to LFOT, compared with regular LFOT in people with CRF due to chronic obstructive pulmonary disease (COPD) or interstitial lung
INTRODUCTION: People with longstanding hip and groin pain (LHGP) are often referred to orthopaedic care. Physical therapist-led interventions are recommended in consensus statements as the first line of treatment, but it is unknown if structured interventions are more effective than usual care. The aim of this trial is to evaluate the effectiveness of a structured physical therapist-led treatment
Context: Life satisfaction (LS) is associated with health and longevity but decreases after spinal cord injury (SCI). Yet, little is known about changes in LS over time, many years after SCI. Objectives: To assess changes in LS over six years among older adults aging with long-term SCI, determine how changes in LS are associated with sex, age, injury characteristics, and with changes in secondary
Populärvetenskaplig sammanfattning: Målsättningen med detta arbete är att ta fram en metod för att kartera och analysera den rumsliga variationen av landskapets sårbarhet för miljögifter, samt att visa hur geografiska informationssystem (GIS) kan underlätta denna rumsliga kartering och analys. Analysen utfördes inom vattenskyddsområdet Ignaberga-Hässleholm i Hässleholms kommun. Först studerades
Background: There is mounting evidence supporting the role of the microbiota in hypertension from experimental studies and population-based studies. We aimed to investigate the relationship between specific characteristics of the gut microbiome and 24-h ambulatory blood pressure measurements. Methods: The association of gut microbial species and microbial functions, determined by shotgun metagenom
