Nuclear medicine is based on the radiotracer principle of George de Hevesy and the magic bullet concept by Ehrlich and focuses on the diagnosis, the treatment of diseases and the investigation of normal states within the human body using radiopharmaceuticals. A radiopharmaceutical is an atom or a chemical compound in which one or several atoms are replaced with a radionuclide. Several diagnostic a

Plants produce a multitude of different compounds that may have biotic effects. Artemisia annua, produces a compound used as a drug against multi-drug-resistant strains of Plasmodium falciparum, the parasite causing malaria. The compound, artemisinin, is a sesquiterpene and is an essential component for the production of artemisinin drugs against malaria. In a first critical step of the biosynthes

This thesis mainly focuses on methods for improving and evaluating Spatial Data Infrastructures (SDIs). The aim has been threefold: to develop a framework for the management and evaluation of an SDI, to improve the accessibility of spatial data in an SDI, and to improve the cartography in view services in an SDI. Spatial Data Infrastructure has been identified as an umbrella covering spatial data

Fracture incidence is higher in urban than in rural inhabitants. Background factors such as physical activity and workload may have an influence on the tendency to fall, leading to fractures. We found that elderly women with a recent fracture of the distal radius appear to have impaired balance, an impairment that seems to normalise with time after fracture. The aim of this study was also to get n

The grammatical marker LE in Mandarin Chinese can occur in two syntactic positions, either immediately following the verb or at the end of a sentence. Traditionally, it has been described as two homophonous but syntactically distinct morphemes, verbal LE and sentence-final LE. This view seems to be based on assumptions about (1) the historical origin of LE, (2) the relation between LE and its coun

Hemodilution reduces the need for blood transfusion and hereby the risk for transmission of infectious agents. The present study investigated effects on systemic and myocardial circulation and oxygenation, and blood lactate concentrations; induced by nitrous oxide, isoflurane, hypoxia, and uncompensated blood loss, in pigs hemodiluted to a hematocrit of 11%. In addition, indicators of hypovolemia

This thesis presents a new verification concept, the virtual accelerator, for dose calculation algorithms used in treatment planning systems (TPSs) for external beam radiotherapy. The algorithm input data required to implement a treatment unit in the TPS are generated by Monte Carlo simulations as are the beam reference data needed for the subsequent evaluation of the dose calculation algorithm. T

Most components in use in our society have undergone a machining process at some stage within its manufacturing cycle. As a result, the economics of the machining process plays an important role in the manufacturing costs. There are several reasons for developing a rational approach to material removal, such as improving cutting techniques, producing products with enhanced precision, and increasin

The topic of this work is simulations of porous materials and transport phenomena at a mesoscopic length scale, i.e., a length scale larger than an individual atom but smaller than the continuum. The porous material studied is a membrane used in fuel cells. Mass transfer has also been studied in the membrane. Heat and mass transfer has been studied in parallel plate channels, first in saturated ch

Climate projections indicate that Arctic and sub-Arctic regions are facing a significant change in climate during the 21st century. With warmer temperatures precipitation is also expected to increase, and in particular winter precipitation. These changes are likely to have large impacts on the Arctic and subarctic environment, and extensive research has focused on ecosystem-climate interactions in

With the aid of modern computer technology the application of visualization and simulation technology has become increasingly important in today’s society. Through computer modelling it is possible to experience, understand and explore environments, systems or objects in two or three dimensions and to see, hear and sometimes tangibly feel them. It may be environments or objects that do not yet exi

The gastrointestinal tract has two opposing functions; to absorb nutrients and electrolytes, and to act as a barrier towards hazardous and non-nutritional substances. In the present thesis the barrier function of the gastrointestinal tract was studied in animal models in vivo, in situ and in vitro. Experimentally induced disorders of the intestinal barriers were evaluated in terms of altered inte

The verbal system of Biblical Hebrew has intrigued the minds of exegetes, linguists, theologians, and translators for centuries. With regard to the verbal system, Biblical Hebrew is radically different from Modern Hebrew. Furthermore, it doesn't fit the traditional structure of grammar modelled on Latin. It is argued that the interpretive categories of aspect, temporal location, and modality shou

The use of multi-antenna systems with multiple-input multiple-output (MIMO) technology will play a key role in providing high spectrum efficiency for next generation mobile communication systems. This thesis offers valuable insights on the design of compact multi-antennas for efficient MIMO communications. In the course of the thesis work, several novel six-port antenna designs have been proposed

This thesis describes the epitaxial growth of III-V semiconductor nanowires using Au seed particles, and the design of more complex three-dimensional branched structures from these wires. Growth was performed by metallorganic vapour phase epitaxy, in which precursor molecules for the semiconductor material components are introduced in a low-pressure vapour. Nanowires grow epitaxially (with control

The overall goal of this thesis is to test new detector technologies and data acquisition systems, for use in Ion Beam Analysis IBA. This is intended to complement the existing setup, which is routinely used at Lund Ion beam Analysis Facility LIBAF. Proton induced X-ray emission is a well-known method for trace element analysis of heavier elements, but trace element analysis of elements below alum

The functions of proteoglycans often depend on the fine structure of the covalently attached glycosaminoglycan (GAG) side-chains. The process leading to the mature GAG is complex and involves a multitude of different enzymatic steps. GAG synthesis is initiated on serine residues, where a xylose residue is transferred to the protein core, a reaction catalyzed by a xylosyltransferase (XT). It therea

Alcoholic beverage marketing communication has been observed to be highly, and stereotypically gendered. However, there is a common misconception that men and women are fundamentally different in their alcoholic beverage preferences and behaviours, therefore questioning the appropriateness of segregating products based on gender. Not only has this binary approach to gender been proven to create si

Denna uppsats behandlar svenska advokaters tystnadsplikt utifrån ett kritiskt och advokatideologiskt perspektiv. Uppsatsen redogör för vilka dessa advokatideologier är, vilka argument de grundas på och vilken effekt ideologierna har för tystnadsplikten. Uppsatsen redogör för tystnadspliktens syfte, dess aktualiserande och dess olika motstående intressen. Uppsatsen redogör även för de lagar och re