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https://www.ht.lu.se/en/course/%C3%96VSG03/ - 2026-08-14

Background It is estimated that 34 million people suffer from dementia, costing society US$422 billion each year. Alzheimer’s disease (AD) is the most common dementia and the global prevalence is predicted to increase to over 100 million people by the year 2050, with the greatest increase in developing countries. Therefore, inexpensive and efficient instruments are required for investigation and e

Arctic ecosystems play a key role in the terrestrial carbon (C) cycle, but spa-tially explicit data on the C exchange is scarce in these remote areas. The global warming is especially dominant in the Arctic, and these areas are vul-nerable to climate change. It is therefore important to quantify and understand the processes affecting the C dynamics in these regions. In this thesis, the land-atmosp

Diabetes wounds result in significant morbidity, prolonged hospitalization and huge health care expenses. As of yet, no optimal animal models of diabetic wound healing exist to study potential beneficial therapies. Porcine wound healing is very similar to human wound healing. We stipulated that by inducing diabetes in yorkshire pigs, wound healing would be delayed and exhibit abnormalities similar

Supported housing facilities (SHF) are among the most common housing solutions for people with severe mental illness (SMI). A poor level of physical-environment qualities and the re-creation of institutional atmospheres in these settings have been found in recent studies. The research focus in the psychiatric field has, however, largely neglected these topics and the available knowledge does not p

Valuating a company is traditionally a finance subject that requires a deep analysis of a company’s financial history and projections about its future potential to generate revenue. When it comes to technology startups, valuation becomes difficult. Startups are, by definition, newly established companies with insufficient historical data. Future revenue is typically problematic to forecast as they

Epilepsy is a syndrome characterized by recurring attacks of sudden, excessive and synchronous discharge in populations of cerebral neurons. Kindling is an animal model for complex partial epilepsy, and is particularly useful for studies on the development of the abnormal excitability underlying the generation and spread of epileptic seizures. Here we have used the kindling model to investigate me

A comparison of essential oils from leaves of Eucalyptus camaldulensis Dehn. obtained by hydrodistillation (HD) and supercritical carbon dioxide (SC-CO2) extraction is presented. Selected major components of the oils showed a predominance of higher molecular weight components in the SC-CO2 extracts than in those obtained by HD. Physico chemical properties such as molecular weight, vapour pressure

The aim of the thesis is to contribute to knowledge of (1) psychosocial illness in the population, (2) the prevalence and nature of psychosocial illness encountered in primary health care, and (3) encountered among persons with long-term illness. The data collected include the results of a questionnaire given to a population-based sample of 13 000 persons (20-84 years), a questionnaire given to ge

The serotonergic vascular control was investigated by in vitro pharmacology in the human uterine and umbilical arteries. The localisation of immunoreactive (IR) neuropeptide Y (NPY) and the influence of NPY on the adrenergic vascular effects in the human uterine artery were also studied. NPY-IR nerve fibres were observed predominantly at the media-adventitial border of the uterine artery. About 50

This thesis concerns clean and adsorbate covered metal surfaces and surface alloys. These systems have been studied using theoretical and experimental methods. In the first part of the thesis, the different techniques that have been utilized in this work are presented, and the included publications are summarized. The second part of the thesis consists of seven original publications. In the first

It is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. The eye contains several highly specialized tissues, in which the protein turnover is of vital

Purpose: To study dark adaptation in patients with symptomatic carotid artery disease or polycythemia before and after treatment. This necessitated determinations of pupillary changes as such may influence the findings. To determine whether changes in the retinal blood flow in light and darkness occur in healthy humans. Methods: Repeated automatic dark adaptometry was recorded monocularly in 21 c

Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. However, they contain a sequence resembling the consensus binding sequence of the major t

In this thesis, I present both theoretical and empirical work where we have studied how humans and animals use information in situations where they need to continually update their information on the density of a resource. We have found that the amount of information, and the way the information is presented, are important factors for how well decisions are adapted to current circumstances. In an

The intention of this work was to establish alternative purification methods to obtain highly purified caveolae from various tissues. In order to isolate caveolae, sufficiently pure plasma membranes are needed. A method is presented for the isolation of plasma membranes from lung tissue using a combination of conventional polyethylene glycol/dextran two-phase partitioning and affinity partitioning

In this thesis, electron transport in mesoscopic semiconductor nanostructures, in particular so-called electron billiards or quantum dots, is studied. The thesis can be divided into two areas: the linear response regime of transport, and the nonlinear response regime of transport. The classical and quantum mechanical electron dynamics are studied for triangular and square-shaped electron billiard

The aim of this Master's thesis is to construct an algorithm that nds the optimal credit limit for an individual credit card holder. It should be optimal in the sense that the algorithm suggests the lowest credit limit required for reaching the business goal of generating "X SEK within d days after limit raise" for the issuer of the credit card. This is achieved in three stages. Firs

Movement and dispersal are important determinants of the spatial distribution and persistence of animal populations in a heterogeneous environment. I studied the small-scale movement pattern of a soil-living insect, Protaphorura armata (Collembola) by using a video-equipment. I added chemical cues, food and conspecifics to their environment and evaluated the effects of external cues on the movemen