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Introduction: The aims were to investigate 1) the frequency of nonsurgical retreatment, root-end surgery, extraction, and further restorative treatment during a follow-up of 10–11 years after root filling and compare the frequencies according to tooth group and type of coronal restoration and 2) the timing of nonsurgical retreatment, root-end surgery, and extraction. Methods: Data were collected f

BACKGROUND: Thanks to improved medical care, individuals with spina bifida (SB) live well into adulthood and go through the process of reproductive maturation and the development of sexual desires. However, access to reproductive counselling and contraceptive use has been reported to be lower for women with physical and intellectual disabilities compared to the general population.OBJECTIVE: We inv

Few studies have evaluated the implementation of ICBT in regular child and adolescent mental health services (CAMHS). This study aimed to explore the acceptability, feasibility, and effectiveness of ICBT for children and adolescents with anxiety disorders and obsessive-compulsive disorder (OCD) within a rural CAMHS. The study also explored outcome predictors and long-term outcomes. Eighty-three pa

Introduction: Resting heart rate has been distinctly related to both internalizing (high pulse) and externalizing (low pulse) disorders. We aimed to explore the associations between resting heart rate and suicidal behavior (nonfatal suicide attempt [SA] and suicide death [SD]) and evaluate if such associations exist beyond the effects of internalizing/externalizing symptomatology. Method: We used

Background: Multiple myeloma (MM), an incurable disease characterized by frequent relapses and a need for multiple treatments, often progresses to a relapse/refractory status resistant to all available drugs and drug classes. Bispecific antibodies, specifically BCMA T-cell engagers, have emerged as effective treatments for MM, demonstrating impressive efficacy. However, these treatments can advers

Multi-archive studies of climate events and archive-specific response times require synchronous time scales. Aligning common variations in the cosmogenic radionuclide production rate via curve fitting methods provides a tool for the continuous synchronization of natural environmental archives down to decadal precision. Based on this approach, we synchronize 10Be records from Western Gotland Basin

In recent years, there has been a paradigm shift in the building sector towards more sustainable, resource efficient, and renewable materials. Bio-based insulation derived from renewable resources, such as plant or animal fibres, is one promising group of such materials. Compared to mineral wool and polystyrene-based insulation materials, these bio-based insulation materials generally have a sligh

Floods and wildfires are two critical hazards that impose substantial direct and indirect costs to society, including the resource needs of rescue services. Their occurrence is strongly linked to meteorological conditions, playing a fundamental role in hazard development and assessment. These hazards are notably distinguishable due to opposing weather requirements, wet conditions for floods and dr

Background and objective: There is an unmet need to avoid long-term morbidity associated with standard cytotoxic treatment for low-volume metastatic seminoma. Our aim was to assess the oncological efficacy and surgical safety of retroperitoneal lymph node dissection (RPLND) as treatment in a population-based cohort of metastatic seminoma patients with limited retroperitoneal lymphadenopathy. Metho

Previous studies have found that elites differ from the general population not only in terms of their demographic and social composition but also with respect to policy preferences and attitudes. When it comes to civil society organisations, the issue of representation and representativeness of top-level leadership is of particular relevance, since a small number of individuals are expected to act

Industrial symbiosis (IS) has been recognized as an important approach to succeed in the transition towards increased circularity in industry and society. IS involves collaboration between different actors sharing resources, aiming to minimize waste, improve resource and/or energy efficiency, resulting in reduced emissions and environmental impact. This study conducts an embedded single case study

Background The adverse health effects associated with long commutes provides additional evidence of the commuting paradox. Better job opportunities and higher incomes in larger local labour markets are offset by the negative consequences of longer commutes including lower levels of life satisfaction. Long commutes extend the work day and time spent commuting is time lost for health beneficial actiThe adverse health effects associated with long commutes provides additional evidence of the commuting paradox. Better job opportunities and higher incomes in larger local labour markets are offset by the negative consequences of longer commutes including lower levels of life satisfaction. Long commutes extend the work day and time spent commuting is time lost for health beneficial activities such