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The 20th century, as well as the 21st, is ripe with hermeneutic anxiety concerning the survival of the object of interpretation and the right way to study literature. In this thesis, the Canadian scholar-poet Anne Carson is studied as a framework to an understanding of how poetry and literary criticism – the event of hermeneutics – co-occur, converge, and diverge. Specifically, it studies Carson’s
Miljoner människor faller årligen offer för människohandel världen över och efterfrågan på framförallt kvinnor och barns sexuella tjänster är stor. Sverige har en unik lagstiftning mot köp av sexuella tjänster med nära koppling till och avskräckande effekt på människohandelsindustrin. För att möjliggöra mer nyanserade bedömningar, exempelvis i fall där den som erbjuder tjänsten är offer för männisEach year millions of people are victim of human trafficking and the demand for women’s and children's sexual services is particularly high. Sweden has a unique law criminalizing the purchase of sexual services, which is closely linked to the human trafficking industry. On July 1st, the maximum penalty for the purchase of sexual services will be raised to imprisonment for one year. This will a
The offence rape is a phenomenon in Swedish criminal law that engages many people and often creates vivid reactions when media reports about verdicts of acquittal in cases involving rape. The rape section has been changed at multiple times over the years. The last change entered into force July 1, 2013 when the new concept ”particularly vulnerable situation” (”särskilt utsatt situation”) replaced
Fluid biomarkers are revolutionizing the diagnosis and management of neurodegenerative diseases by enabling earlier diagnosis and disease monitoring. In particular, blood-based biomarkers have emerged as a minimally invasive and scalable alternative to cerebrospinal fluid analysis. Recent advances in blood-based tau biomarkers have shown high diagnostic accuracy for Alzheimer’s disease (AD). Other
In 2018, Sweden passed a new law regarding rape, which is based on the lack of voluntary participation or in other words, consent. This means that it is now the perpetrators intent, regarding that the other person does not participate voluntarily in the sexual act, which lays in the court judgements focus. Another change was that a new offense where passed, negligent rape. Thus, criminal liability
Från och med den 1 januari 2020 skärptes straffskalan för sexköp av barn. Syftet med åtgärden var att förstärka det straffrättsliga skyddet för ungdomar mot att dras in i prostitution. Brottet är förknippat med låg åtalsfrekvens. Det har tidigare förklarats med att aktsamhetskravet i förhållande till ålder i 6 kap. 13 § BrB - som täcker flera sexualbrott med åldersgräns - var särskilt svårt att upIn January 2020 the range of punishment for exploitation of a child through the purchase of a sexual act got stricter. The reasoning behind the change was to strengthen the criminal justice protection for these children. Exploitation of a child through the purchase of a sexual act is associated with a low prosecution frequency. An explanation for this has been that the rule of negligence in the si
Due to the lack of a commonly required education amongst street-level bureaucrats in supported housing, the focus of this study was to analyse how the street-level bureaucrats in supported housing experienced their work and education. We were also interested in how they felt their knowledge and skills were utilized in their organizations. In the last decade, the number of supported housing efforts
The essay examines the application of Section 33 of the Contracts Act (SFS 1915:218), with particular focus on the Supreme Court’s (HD) ruling in the case ‘Nätkasinot’ (T 607-24, 1 July 2025). Section 33, which addresses good faith and honour, has rarely been applied by the courts but has recently gained renewed relevance through the ‘Nätkasinot’ judgment. The purpose of the essay is to analyse th
The Anti-Tax Avoidance Directive (ATAD) was adopted on 12 july and needed to be implemented by the member states on 31 december 2018. The general anti-avoidance rule (GAAR) in article 6 is the interest of this thesis. The purpose with the GAAR is to access the arrangements or transactions that try to circumvent the tax legislation. The GAAR should cover gaps and apply to arrangements that are not
In July 2016, the Law on temporary limitations to the possibility of being granted residence permit in Sweden (the Temporary Law) came into force. The Temporary Law implied a sharp turn in Swedish asylum legislation. The right to family reunification, which previously had been granted subsidiary protection beneficiaries and refugees on a similar basis, was suddenly heavily restricted for beneficia
One of the key ecological processes affected by climate change is plant carbon uptake. However, there is substantial uncertainty about how plant carbon uptake will respond to warming in mountain ecosystems, which are known for sharp temperature gradients and abrupt shifts in vegetation structure. Specifically, we lack an understanding of whether these response trajectories over time will be linear
The Sardinian dhole (Cynotherium sardous) was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene. Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African hunting doThe Sardinian dhole (Cynotherium sardous)1 was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene.2-5 Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African huntin
The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi). In the ZUMA-2 single-arm trial, brexucabtagene autoleucel (brexu-cel; autologous anti-CD19 CAR T-cell therapy) demonstrated high rates of durable response
Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory
INTRODUCTION: We examined whether sex modifies the association between APOE ε2 and cognitive decline in two independent samples. METHODS: We used observational data from cognitively unimpaired non-Hispanic White (NHW) and non-Hispanic Black (NHB) adults. Linear mixed models examined interactive associations of APOE genotype (ε2 or ε4 carrier vs. ε3/ε3) and sex on cognitive decline in NHW and NHB p
Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-Cas9 screen in a human MDS-derived cell line, MDS-L, and identify TOPORS as a loss-of-function target that synergizes with HMAs, reducing leukemic burden and i
PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin
The intronic SNP rs7903146 in the T-cell factor 7-like 2 gene (TCF7L2) is the common genetic variant most highly associated with Type 2 diabetes known to date. The risk T-allele is located in an open chromatin region specific to human pancreatic islets of Langerhans, thereby accessible for binding of regulatory proteins. The risk T-allele locus exhibits stronger enhancer activity compared to the n
Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o
