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BACKGROUND: Helicobacter pylori infection may be a risk factor for pancreatic cancer, particularly infection by strains without the cytotoxin-associated gene A (CagA) virulence factor. Non-O blood type is a known risk factor for pancreatic cancer, and H. pylori gastric colonization occurs largely from bacterial adhesins binding to blood group antigens on gastric mucosa.METHODS: We included 485 pan

Antibodies play a key role in acquired human immunity to Plasmodium falciparum (Pf) malaria and target merozoites to reduce or prevent blood-stage replication and the development of disease. Merozoites present a complex array of antigens to the immune system, and currently, there is only a partial understanding of the targets of protective antibodies and how responses to different antigens are acq

Recent studies highlight the importance of lipotoxic damage in aortic cells as the major pathogenetic contributor to atherosclerotic disease. Since the STE20-type kinase STK25 has been shown to exacerbate ectopic lipid storage and associated cell injury in several metabolic organs, we here investigate its role in the main cell types of vasculature. We depleted STK25 by small interfering RNA in hum

Human blood plasma can be obtained relatively noninvasively and contains proteins from most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma proteins is an important starting point for the discovery of disease biomarkers. In 2005, we showed that different proteomics measurements using different sample preparation and analysis techniques identify significant

Non-invasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer (PCa) therapies. AR is a critical driver and mediator of resistance of PCa but currently available non-invasive PCa biomarkers to monitor AR activity are discordant with downstream AR pathway activity. External beam radiotherapy (EBRT) remains a common tre

BackgroundNon-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk. For many loci, however, the mechanisms through which non-coding variants influence diabetes susceptibility are unknown.ResultsWe examine splicing QTLs (sQTLs) in pancreatic islets fro

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-06-05 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-06/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250605.pdf - 2025-09-30

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-08-25 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-08/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250825.pdf - 2025-09-30

Penningtvätt utgör ett problem för samhällsekonomin, då det innebär ett hot mot det finansiella systemet om pengar med kriminellt ursprung hamnar i den legala ekonomin. Sveriges skydd för att kriminella tillgångar tvättas i den legala ekonomin har visat sig ineffektivt. Financial Action Task Force on money laundering har påpekat bristerna i svensk rätt och rekommenderat åtgärder då det inte finns If money with illicit origins enters into circulation in the financial system it poses a threat to the mechanisms of the financial system. Financial Action Task Force have concluded that the Swedish legal requirements for combating money laundering is insufficient, and the organisation have advised Swedish authorities to effectuate preventive measures. Therefore, the Swedish legal system is not co

Liten blomma i backen, formad av bondens blod, svett och tårar En bit innan semesterparadiset Smögen, ligger en liten ö med mångårig historia. Här har marken odlats under många hundra år. På sommaren slåttrade man gräset, bar det till höbalar, och korna betade lojt på med utsikt över klipporna och havet. Störningarna var stora på gräsmarkerna, lien skar av växterna och korna betade, för många växWith the gain of productivity in farming the last decades, there has been great loss in species richness. Many plant species that have evolved and adapted alongside to traditional farming and benefiting to the managed land use, are now disappearing in great numbers. Three thirds of Sweden’s endangered plant species are those who thrive in managed grasslands like meadows and grazing areas. The trad

The 20th century, as well as the 21st, is ripe with hermeneutic anxiety concerning the survival of the object of interpretation and the right way to study literature. In this thesis, the Canadian scholar-poet Anne Carson is studied as a framework to an understanding of how poetry and literary criticism – the event of hermeneutics – co-occur, converge, and diverge. Specifically, it studies Carson’s

In July 2016, the Law on temporary limitations to the possibility of being granted residence permit in Sweden (the Temporary Law) came into force. The Temporary Law implied a sharp turn in Swedish asylum legislation. The right to family reunification, which previously had been granted subsidiary protection beneficiaries and refugees on a similar basis, was suddenly heavily restricted for beneficia

Från och med den 1 januari 2020 skärptes straffskalan för sexköp av barn. Syftet med åtgärden var att förstärka det straffrättsliga skyddet för ungdomar mot att dras in i prostitution. Brottet är förknippat med låg åtalsfrekvens. Det har tidigare förklarats med att aktsamhetskravet i förhållande till ålder i 6 kap. 13 § BrB - som täcker flera sexualbrott med åldersgräns - var särskilt svårt att upIn January 2020 the range of punishment for exploitation of a child through the purchase of a sexual act got stricter. The reasoning behind the change was to strengthen the criminal justice protection for these children. Exploitation of a child through the purchase of a sexual act is associated with a low prosecution frequency. An explanation for this has been that the rule of negligence in the si

Due to the lack of a commonly required education amongst street-level bureaucrats in supported housing, the focus of this study was to analyse how the street-level bureaucrats in supported housing experienced their work and education. We were also interested in how they felt their knowledge and skills were utilized in their organizations. In the last decade, the number of supported housing efforts

In 2018, Sweden passed a new law regarding rape, which is based on the lack of voluntary participation or in other words, consent. This means that it is now the perpetrators intent, regarding that the other person does not participate voluntarily in the sexual act, which lays in the court judgements focus. Another change was that a new offense where passed, negligent rape. Thus, criminal liability

Under de senaste årtiondena har bin, såsom humlor, minskat i både antal arter och populationsmängder. Detta är ett stort problem för vårt samhälle då både jordbruket och naturliga ekosystem till stor del är beroende av dessa pollinatörer. Det är speciellt problematiskt att humlor minskar då de har förmågan att utföra en speciell sorts pollinering (buzz-pollination) som några av våra vanligaste gröThe decline of bees, such as bumblebees, over the last decades raises concerns as they are key pollinators in both agricultural and natural ecosystems. One proposed cause for the decline of wild bees is competition for food resources with managed honeybees. Detrimental effects of competition can result where co-existing species exhibit a high degree of shared resource use (i.e., niche overlap). Th

Ger pressar dig bra vibrationer? Idag är allt från kaffemaskiner och gräsklippare till krutpistoler och bilar uppkopplade och kan närsom-helst ge oss en statusrapport genom bara ett par klick i en app. Vi kan med mobilen kolla bilens bräns-lenivå, geografiska position eller om vi glömt att låsa på väg in från par-keringen. Så varför skulle inte statu-sen på utrustningen som används för att tillveIn a world where the concept of just-in-time has been lifted outside of the manu-facturing world and onto the market, the increasing demand of luxury wares like cars is accompanied only by tougher industrial conditions and no room for error. Loss of productivity and decrease in efficiency can be devastating to any manufac-turing company in today’s market climate. One of the largest causes of these

The Anti-Tax Avoidance Directive (ATAD) was adopted on 12 july and needed to be implemented by the member states on 31 december 2018. The general anti-avoidance rule (GAAR) in article 6 is the interest of this thesis. The purpose with the GAAR is to access the arrangements or transactions that try to circumvent the tax legislation. The GAAR should cover gaps and apply to arrangements that are not

Förbättring av bildkvalité med hjälp av kristaller! Alla som någon gång har försökt att ta en bild vet den stora vikten av att ha bra fokus i bilden och hur störigt det är när man inte får till bra bildkvalité. Dagens kameror har blivit känsligare och det är idag viktigare än någonsin att alla komponenter i kameran finns på rätt plats. Bara några mikrometers skillnad på placeringen av bildsensornThe use of piezoelectric crystals as a way to achieve automatic alignment of an image sensor in a camera was investigated in collaboration with Axis Communications AB. Piezoelectric crystals can be created into different configurations, piezoelectric stacks being one of the simpler ones. By attaching three piezoelectric stacks behind an image sensor and applying voltage to the stacks, they expand