Objective: To characterize visual function in defined genotypes including siblings with Usher syndrome. Methods: Thirteen patients with phenotypically different subtypes of Usher syndrome, including 3 families with affected siblings, were selected. Genetic analysis and ophthalmological examinations including visual fields, full-field electroretinography (ERG), multifocal electroretinography (mf ER

It is generally maintained that learning should be a part of the daily routines of many organizations; this is often referred to as lesson learned processes. The purpose of organizational learning is to foster improvements that seek to both reduce incidents and accidents and reduce their consequences when they nevertheless happen. Safety work is widespread among many organizations, e.g. aviation,

An efficient and well-performing double-talk detection (DTD) algorithm is a vital part of a practically working acoustic echo canceller. However, recent algorithms are typically evaluated using a static time-invariant room acoustic impulse response, omitting a proper treatment of the case when the acoustic path is changing. In this work, we introduce a common framework to objectively evaluate how

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. At an early stage of the disease, AF may terminate spontaneously and is then referred to as paroxysmal AF. On the other hand, when external intervention is required for the arrhythmia to terminate, it is referred to as persistent AF. In this work, a method to discriminate between paroxysmal and persistent AF in the long-t

Standing postural stability relies on input from visual, vestibular, proprioceptive and mechanoreceptive sensors. When the information from any of these sensors is unavailable or disrupted, the central nervous system maintains postural stability by relying more on the contribution from the reliable sensors, termed sensory re-weighting. Alcohol intoxication is known to affect the integrity of the v

Under en sexmånaders period beslutade Försäkringskassan i fem län att avslå eller dra in sjukpenningen helt eller delvis i 538 ärenden. De försäkrade bedömdes inte vara arbetsoförmögna till följd av sjukdom. I den här undersökningen visas att risken för negativt beslut varierar kraftigt för olika diagnoser och att det är vissa typer av sjukdom och ohälsa som fastnar i den skärpta gränskontrollen.

BACKGROUND AND PURPOSE: Previous reports concerning sex-related differences in stroke management and outcome are inconsistent and are sometimes difficult to interpret. We used data from a national stroke register to further explore possible differences between men and women in baseline characteristics, stroke treatment, and outcome. METHODS: This study included 24 633 stroke events registered in R

Review of "Børglum Domkirke og Kloster i middelalderen" (2013)

This is a review of the panel “Metalepsis out of Bounds” presented at the 2013 ENN conference. The three convenors proposed complementary remarks to the extent that they either questioned the conceptualization, examined the functioning of metalepsis or applied theoretical models to textual material. Beside an in depth reflection upon the concept, broader questions concerning narrative and popular

In this article we describe and discuss implementation of a weighted simulation procedure, importance sampling, in the context of nonparametric linkage analysis. The objective is to estimate genome-wide p-values, i.e. the probability that the maximal linkage score exceeds a given threshold under the null hypothesis of no linkage. In order to reduce variance of the p-value estimate for large thresh

Past land use change has converted vast areas of Northern peatland by drainage to agricultural or forested land. This change often reduces the greenhouse gas (GHG) sink strength of peatlands or turns them even from sinks to sources, which affects the global climate. Therefore, there is a need for suitable mitigation options for GHG emissions from drained peatlands. Addition of wood ash to peatland

Microstructure evolution in thin Cu films during room temperature self-annealing is investigated by means of a mesoscale level set model. The model is formulated such that the relative, or collective, influence of anisotropic grain boundary energy, mobility and heterogeneously distributed stored energy can be investigated. Density functional theory (DFT) calculations are performed in the present w