Production, purification and characterization of antibacterial biomolecules from an alkaliphilic Bacillus
Popular Abstract in English As there is a demand for new antibacterial agents due to antimicrobial resistance, the ability of one kind of microorganisms to produce antimicrobial substances has been evaluated. Then, after determining the antibacterial-producer microorganism, the production of active compound in large scale, followed by optimization the conditions investigated. Next, the bioactive aForty alkaliphiles, which were isolated from samples collected in Eastern Africa, have been screened for production of antibacterial compounds. One of these isolates, Bacillus halodurans B20, was able to produce a prominent amount of antibacterial activity against a Gram-positive bacteria on agar plates [paper I] and selected for further study. Production of the active compound in submerged culti
