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Lärande över nätet innebär ett förändrat tänkande för både lärare och studenter. Med den lyckade fort- och vidareutbildningskursen medicinsk fysik för gymnasielärare som exempel, diskuteras i det följande lärandemodell, erfarenheter och faktorer som är viktiga för att nå framgång med en kurs. Det primära syftet med kursen är att ge fysiklärare bättre förutsättningar att undervisa fysik och teknik
Popular Abstract in Swedish När en organism utsätts för stress, t. ex. vid hög temperatur, starkt solljus, torka eller köld, produceras särskilda hjälpar-proteiner, s. k. ¨stress-proteiner¨. Syntesen av cellens normala proteiner stängs av och istället produceras bara stress-proteiner. Dessa stress-proteiner är till för att skydda andra protein som skadas under stress. De s. k. ¨värme-stress¨ proteA specific group of heat shock proteins, the so called small heat shock proteins (sHsps), exists in all organisms but are especially abundant in plants. The sHsps prevent aggregation of other proteins (substrate proteins) during transient heat and oxidative stress. Molten globule forms of the substrate proteins are kept in a re-folding competent state by binding onto the outer surface of the sHsp.
Popular Abstract in English 111-Indium is a radioactive isotope that can be chemically linked to different molecules. When this compound is given to patients is distributed heterogeneously within the structures that build up the testicle. Different parts of the so-called germ cells are sensitive to radiation in different ways. Therefore, if a radioisotope that send out electrons with low energies It is well known that the testicles are among the most radiosensitive tissue, and constitute an important critical target for both external and internal radiation during diagnostic and therapeutic use of radionuclides. In systemic radionuclide therapy where very high activities are administered, the testis may become a dose-limiting organ; often with a complex, non-uniform activity distribution an
Aims: To investigate associations between trust in the healthcare system and all-cause, cardiovascular, cancer and other causes mortality. Study design: Prospective cohort study. Methods: A public health questionnaire was conducted in 2008 in Scania, the southernmost part of Sweden, with a 54.1% participation rate with a postal questionnaire and three reminders. In this study 24,833 respondents we
In Kenya, HIV-1 key populations including men having sex with men (MSM), people who inject drugs (PWID) and female sex workers (FSW) are thought to significantly contribute to HIV-1 transmission in the wider, mostly heterosexual (HET) HIV-1 transmission network. However, clear data on HIV-1 transmission dynamics within and between these groups are limited. We aimed to empirically quantify rates of
Prostate apoptosis response-4 (Par-4) is a tumor suppressor that induces apoptosis in cancer cells. However, the physiological function of Par-4 remains unknown. Here we show that conventional Par-4 knockout (Par-4-/-) mice and adipocyte-specific Par-4 knockout (AKO) mice, but not hepatocyte-specific Par-4 knockout mice, are obese with standard chow diet. Par-4-/- and AKO mice exhibit increased ab
Non-linear materials such as upconverting nanoparticles (UCNPs) are emerging technology with fast-growing applications in various fields. The power density dependence of the emission quantum yield (QY) of these non-linear materials makes them challenging to characterize using currently available commercial QY systems. We propose a multimodal system to measure QY over a wide dynamic range (1:104),
The aim of this study was to explore whether social workers can become more explicit about their knowledge use if they are assisted in analyzing the rationales underlying their conclusions about diagnosis and treatment. By dissecting the rationales provided by 46 Swedish social work practitioners and students in response to two case vignettes describing vulnerable children and their families, and
Human cholangiocyte organoids show great promise for regenerative therapies and in vitro modeling of bile duct development and diseases. However, the cystic organoids lack the branching morphology of intrahepatic bile ducts (IHBDs). Here, we report establishing human branching cholangiocyte organoid (BRCO) cultures. BRCOs self-organize into complex tubular structures resembling the IHBD architectu
In collective harm cases, bad consequences follow if enough people act in a certain way even though no such individual act makes a difference for the worse. Global warming, overfishing and Derek Parfit’s famous case of the harmless torturers are some examples of such harm. Shelly Kagan argues that there is a threshold such that one single act might trigger harm in all collective harm cases. Julia
