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This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were included. Renal involvement was defined by DMSA scans and molecular disease determinants by gene expression analysis and proteomic screens, at diagnosis and after 6 mo. Innate i
Theoretical work suggests that reinforcement can cause the strengthening of prezygotic isolation in sympatry by mitigating the costs of maladaptive hybridization. However, only a handful of studies have simultaneously tested multiple predictions of this theory in natural populations. We investigated reinforcement in a mottled hybrid zone between the damselflies Ischnura elegans and Ischnura graell
If policy meets its intended goals or not is important in the context of energy transition. We explore if a policy, the EU Taxonomy, designed to foster green investments, meets its intent. We built an overall understanding about the EU Taxonomy by reviewing literature and EU Taxonomy documents. Additionally, we test constraints from the EU Taxonomy on CO2 emissions and on new investments in fossil
Background and Objectives: Temporomandibular disorders (TMDs) is an umbrella term for pain and dysfunction involving jaw muscles and/or the temporomandibular joint, with whiplash trauma suggested to be one risk factor. The aim was to evaluate prevalence and relative risk of TMDs in the acute and chronic stages after whiplash trauma. Databases and Data Treatment: This review was registered in Prosp
The leadership literature has been faulted for framing leaders (and followers) as rational and disembodied information processers. This chapter presents a review of studies that go against this tendency by focusing on how materiality, embodiment, and aesthetics are involved in leadership communication. A number of different perspectives are highlighted in relation to the three focal themes, as welThe leadership literature has been faulted for framing leaders (and followers) as rational and disembodied information processers. This chapter presents a review of studies that go against this tendency by focusing on how materiality, embodiment, and aesthetics are involved in leadership communication. A number of different perspectives are highlighted in relation to the three focal themes, as wel
This study is concerned with the shared object manipulation problem in a physical Human-Robot Interaction (pHRI) setting. In such setups, the operator manipulates the object with the help of a robot. In this paper, the operator is assigned with the lead role, and the robot is passively following the forces/torques exerted by the operator. We propose a controller that is free from the well-known tr
Poor survival for breast cancer in low- and middle-income countries is largely attributed to late-stage diagnosis and limited access to diagnostic tools. Therefore, we propose using point-of-care ultrasound (POCUS) as a low-cost diagnostic solution paired with a deep learning (DL) model for cancer detection. While using DL has shown great potential, it is crucial to ensure the trustworthiness of a
Den nya nationalistiska högern avfärdar FN, klimatavtal och universella mänskliga rättigheter. Sveriges regering har slagit in på samma väg, skriver Adam Almqvist och Anna Lundberg, forskare vid Lunds universitet.
BACKGROUND: Human diets account for 30% of greenhouse gas emissions (GHGE). Reporting dietary GHGE with or without energy standardization yields different outcomes, often resulting in conflicting conclusions regarding associations with micronutrient intake.OBJECTIVES: To compare methods of reporting dietary GHGE, with and without consideration of energy intake, and their respective associations wi
We present a novel acoustofluidic chromatography platform for high-throughput nanoparticle trapping and enrichment, with a focus on extracellular vesicles (EVs) from blood plasma. The system features a packed bed of polystyrene beads inside a rectangular glass capillary, acoustically actuated by a piezoelectric element. Using fluorescent polystyrene nanoparticles as small as 25 nm, we characterize
OBJECTIVES: Early diagnostic separation between glioblastoma (GBM) and solitary metastases (MET) is important for patient management but remains challenging when based on imaging only. The objective of this study was to assess whether amide proton transfer weighted (APTw) MRI alone or combined with dynamic susceptibility contrast (DSC) MRI parameters, including cerebral blood volume (CBV), cerebra
High-order harmonic generation (HHG) in gases is inherently inefficient, prompting ongoing efforts to enhance the output of coherent table-top XUV sources. In this study, we investigate the influence of the laser pulse duration on HHG using a compact post-compression method featuring a bulk multi-pass cell. This setup enables tunable Fourier-limited pulse durations as short as 42 fs. We examine th
This article explores the evolving legal landscape of environmental protection in armed conflict, emphasizing the critical contributions of the icrc Environmental Guidelines and the principles developed by the International Law Commission’s (ilc) on Protection of the Environment in relation to Armed Conflict (perac principles). By incorporating scientific insights and increasing environmental awar
Medieklimatet påverkar inte bara hur politiken kommuniceras utan också vilken politik som formuleras. Kanske är det vi ser i Vita huset medialiseringens logiska slutpunkt: politik som helt underordnad algoritmerna, en ständigt eskalerande reality-show.
Background, Motivation, and ObjectiveThe demand for tissue-mimicking materials (TMMs) is increasing alongside the advancement of hybrid imaging such as photoacoustic imaging (PAI). Developing suitable TMMs for PAI is challenging due to the need to mimic both optical and acoustic tissue properties. The TMMs with tunable properties are needed for the calibration of these imaging modalities, as well
In hospitals, IV bags can be prepared in advance for logistical and microbial safety reasons in a compounding unit and then transported to wards. Transport of protein drugs using a pneumatic tube system has been reported to result in high particle levels. In this study, pneumatic tube transport of trastuzumab in saline polyolefin bags was compared to delivery by hospital porters using an electric
Protein drugs, such as therapeutic antibodies, are complex and require careful handling to maintain their efficacy and quality. Stress factors in hospitals, like temperature variations and mechanical shocks during transport, may negatively impact the stability of protein drugs (e.g. various monoclonal antibodies). The pharmaceutical industry possesses extensive knowledge about their product formul
