BACKGROUND: To determine if the common Pro12Ala polymorphism (rs1801282) of the peroxisome proliferator-activated receptor (PPARG) gene is associated with the metabolic syndrome (MetS) or with its individual components in middle-aged Swedish individuals. METHODS: MetS was defined according to the National Cholesterol Education Program/Adult Panel III (NCEP/ATP III), the International Diabetes Fede

A search for highly ionising, penetrating particles with electric charges from vertical bar q vertical bar = 2e to 6e is performed using the ATLAS detector at the CERN Large Hadron Collider. Proton-proton collision data taken at root s = 7 TeV during the 2011 running period, corresponding to an integrated luminosity of 4.4 fb(-1), are analysed. No signal candidates are observed, and 95% confidence

Helsingborg, a coastal city in southern Sweden, initiated a long-term redevelopment project called H+ in 2009, aiming to convert industrial harbor space in the city's south into a new, livable urban neighborhood and city center. The project aims to create an open and ‘tolerant city’ in Helsingborg over the next twenty years. In 2010-2011, H+ used an open-source planning method as a strategy to inc

Sudden changes of channel coefficients in a wideband vectored wireline system (such as G.fast) due to changes in the terminating impedance of lines outside the vectored group can seriously degrade stability and throughput. This letter presents a model that predicts the impact of termination mismatch based exclusively on crosstalk data for the properly-terminated state. Experimental results confirm

Long-range, seasonal migration is a widespread phenomenon among insects, allowing them to track and exploit abundant but ephemeral resources over vast geographical areas. However, the basic patterns of how species shift across multiple locations and seasons are unknown in most cases, even though migrant species comprise an important component of the temperate-zone biota. The painted lady butterfly

Referring to historiographical tendencies and philosophical discourses on the use of history, the article presents a personal argument for the usefulness of the historian's craft today. Drawing on the research on violence, friendship, and silences in history, it would seem we need penetrating methods when examining the information and disinformation spread widely by the mass media and the Internet

Columnar cell hyperplasia (CCH) is the earliest histologically identifiable breast lesion linked to cancer progression and is characterized by increased proliferation, decreased apoptosis and elevated oestrogen receptor α (ERα) expression. The mechanisms underlying the initiation of these lesions have not been clarified but might involve early and fundamental changes in cancer progression. MiRNAs

We report on the observation of the bright, long gamma-ray burst, GRB 090926A, by the Gamma-ray Burst Monitor and Large Area Telescope (LAT) instruments on board the Fermi Gamma-ray Space Telescope. GRB 090926A shares several features with other bright LAT bursts. In particular, it clearly shows a short spike in the light curve that is present in all detectors that see the burst, and this in turn

In a recent genome-wide association study, WD-repeat domain 12 (WDR12) was associated with early-onset myocardial infarction (MI). However, the function of WDR12 in the heart is unknown.

Agri-environment schemes (AES) have been suggested to counter negative effects of agricultural intensification and enhance farmland biodiversity, but evaluations have produced inconsistent results. We suggest that this is partly a consequence of scale-dependence, i.e. that the consequence of organic farming will differ depending on the scale of uptake in a particular landscape. To test our hypothe

Industrial robots are traditionally programmed using only the internal joint position sensors, in a sense leaving the robot blind and numb. Using external sensors, such as cameras and force sensors, allows the robot to detect the existence and position of objects in an unstructured environment, and to handle contact situations not possible using only position control. This thesis presents work on

In T cells PKC theta mediates the activation of critical signals downstream of TCR/CD28 stimulation. We investigated the molecular mechanisms by which PKC theta regulates NF kappa B transactivation by examining PKC theta/beta single and double knockout mice and observed a redundant involvement of PKCh and PKC beta in this signaling pathway. Mechanistically, we define a PKC theta-CYLD protein compl

Popular Abstract in Swedish Ordet vaskulit betyder kärlinflammation och med systemisk vaskulit menas inflammation i blodkärl på flera olika ställen i kroppen. Vaskulit kan drabba alla typer av kärl i kroppen, både stora och små, artärer, vener och kapillärer. Inflammationen i kärlväggen kan leda till att kärlet skadas och att blodförsörjningen till olika organ då kan bli bristfällig. Symtomen vid ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis- dying neutrophils surrounding small blood vessels. Previous studies have shown increased plasma PR3 and increased proportion of neutrophils expressing plasma membrane-associated PR3 (mPR3+). Neutrophils were isolated by polymorphprep and membrane expression was measured by FACS. Plasma PR3, pro-PR3 and cytokines were

This paper presents an offline frequency-domain nonlinear and stochastic identification method for equivalent model parameter estimation of high-voltage pulse transformers. Such kinds of transformers are widely used in the pulsed-power domain, and the difficulty in deriving pulsed-power converter optimal control strategies is directly linked to the accuracy of the equivalent circuit parameters. Th

Background: Calreticulin (CRT) is a ubiquitous ER protein involved in multiple cellular processes in animals, such as protein folding and calcium homeostasis. Like in animals, plants have evolved divergent CRTs, but their physiological functions are less understood. Arabidopsis contains three CRT proteins, where the two CRTs AtCRT1a and CRT1b represent one subgroup, and AtCRT3 a divergent member.

Aim: The aim of this research was to explore and evaluate the new expected identities of unmarried urban women in China, by analyzing the changes in the marriage law in the last 60 years, particularly in property division in the case of divorce. Methodology: The paper proceeded under the qualitative method and designed a case study in Chengdu. The data from books, journals, policies, newspapers an

In 2003 the concept of Application Service Provision (ASP) as a way to provide Enterprise Systems (ES) to Small and Medium sized Enterprises (SMEs), “hyped”. In 2013 we saw the same “hype” but now with the Software as a Service (SaaS) model. Even if labelled differently, these concepts seem to mean the same and so, in this paper, we explore if providers perspective for the adoption of external pro