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A human milk fraction containing multimeric alpha-lactalbumin (MAL) is able to kill cells via apoptosis. MAL is a protein complex of a folding variant of alpha-lactalbumin and lipids. Previous results have shown that upon treatment of transformed cells, MAL localizes to the mitochondria and cytochrome c is released into the cytosol. This is followed by activation of the caspase cascade. In this st

The purpose of this study was to investigate the effect of enriched environment on motor function after experimental stroke in mice, and to determine whether time in enriched environment affects functional recovery. Earlier investigations have shown that rats placed in an enriched environment after focal ischemia, remarkably improve motor function, but similar observations in mice have not been re

Popular Abstract in Swedish Den fysiska grunden för fysiska aktionsverbThis work is a study of verbal semantics with a focus on the discussion and illustration of the role of body parts and the semantic incorporation into verbal roots of the actions that involve various body parts. Following a general discussion of the basic issues of language construction and human body actions with the image schemas of force-dynamics presented in line with the framework of cognitiv

Background: Crohn's disease is associated with deranged intestinal permeability in vivo, suggesting dysfunction of tight junctions. The luminal contents are important for development of neoinflammation following resection. Regulation of tight junctions by luminal factors has not previously been studied in Crohn's disease. Aims: The aim of the study was to investigate the effects of a luminal stimu

Previously, time/temperature treatments of starch have been performed mainly on starch/water systems. In this study the same time/temperature treatments were applied to starch/water systems and to potato starch in situ. Two potato varieties (Solanum tuberosum cultivars Asterix and Bintje) were used. The effect of time/temperature treatments on gelatinisation behaviour was evaluated using different

The use of intranasal steroids for the treatment of allergic and vasomotor rhinitis has doubled during the past 5 years. The number of reported cases of nasal septum perforation has increased correspondingly. The mechanism behind this is unknown, and steroid-induced septum perforation is rarely described in the literature. In order to describe the course of events and to form an idea of the extent

Boken bygger på en doktorsavhandling från Mannheim 1998 och innehåller en intressant undersökning av den svenska kyrkliga verksamheten i Berlin (den officiella Victoriaförsamlingen) och Wien (den frivilliga Israelsmissionen) under den nationalsocialistiska tiden. Deras hjälpverksamhet för judar eller judekristna markerade distans till regimen och beskrivs som motstånd. Underrubriken lovar dock mer

Prostate specific antigen (PSA) in serum has recently been shown to occur in complex with alpha 1-antichymotrypsin and as an approximately 30 kDa. noncomplexed molecular form. We characterized PSA by 3 different assays in samples from 144 patients with benign prostatic hyperplasia (BPH) and 121 with carcinoma of the prostate. One of these noncompetitive assays measured total PSA by detecting PSA c

The purpose of this investigation was to evaluate the bone turnover by using bone metabolic markers in relation to previous fracture history and independent of bone mass. Patients and controls were recruited from a population-based study of 193 women, all living in the same city and aged 60, 70, and 80 years. The bone mineral content (BMC) was measured bilaterally in the distal forearm by single-p

Macroporous hydrogels (MHs) have been prepared by cross-linking polymerization of hydroxyethyl methacrylate (HEMA) or cross-linking co-polymerization of HEMA with dimethylacrylamide (DMAA) in semi-frozen state. The MHs are elastic and have a unique structure of large interconnected pores with pore sizes up to 100 µm and total porosity of 94–97%, as demonstrated by micro-computed tomography. The st

Static extraction, supercritical fluid extraction (SFE), pressurized liquid extraction (PLE) and Soxhlet extraction were compared for simultaneous extraction of di(2-ethylhexyl) phthalate (DEHP) and nonionic surfactants from house dust. Homogenized office floor dust from a vacuum cleaner dust bag ("standard dust") was used for the evaluation. One portion of the extracts was used for analysis of no

Operation of homogeneous charge compression ignition (HCCI) enginesare very sensitive to timing variations in the combustion of theair-fuel charge mixture and require precise control of the ignitioninstant to run properly. It is therefore essential to understand thecharacteristics of timing variations under various operatingconditions in order to find suitable control strategies. This paperpresent

The cost of energy for drying paper is substantial for the pulp and paper industry, and studies of various strategies for energy cost reductions such as increased energy efficiency, increased heat recovery from the exhaust drying air and reduced cost of the process heat are presented in this thesis. The energy use and cost studies were performed using a block-model based simulation tool developed

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The synthesis of bis-gamma-amino acid dibenzobarrelene derivatives (9,10-bis-aminomethyl-11,12-bis-carboxy-dibenzobarrelene) is presented. Bromomethylation of anthracene followed by azide substitution gave 9,10-bis-azidomethylanthracene. Azide reduction, N-Boc protection, and Diels-Alder cycloaddition in DMAD furnished the protected 9,10-bis-aminomethyl-11,12-dicarboxy-dibenzobarrelene derivative,