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Electrophysiology, Optical Coherence Tomography and Molecular Genetic Analysis in Patients with Glaucoma and/or Best Vitelliform Macular Dystrophy as Part of Clinical Care

Glaucoma is a common ophthalmic disease with multifactorial aetiology. There is growing evidence that glaucoma is a disease of the entire retina and not only the inner retina. Best vitelliform macular dystrophy (BVMD) affects the retinal pigment epithelium and is considered a model system for the more common blinding disease, age-related macular degeneration. The aim of the work presented in this

Ethanol production in biorefineries using lignocellulosic feedstock - GHG performance, energy balance and implications of life cycle calculation methodology

Co-production of high-value biobased products in biorefineries is a promising option for optimized utilization of biomass. Lignocellulosic materials such as agricultural and forest residues have been identified as attractive alternative feedstocks because of their high availability and low resource demand. This study assessed the greenhouse gas (GHG) performance and energy balance of ethanol co-pr

Proposal for quantum spin tomography in ferromagnet-normal conductors

We present a theory for a complete reconstruction of nonlocal spin correlations in ferromagnet-normal conductors. This quantum spin tomography is based on cross-correlation measurements of electric currents into ferromagnetic terminals with controllable magnetization directions. For normal injectors, nonlocal spin correlations are universal and strong. The correlations are suppressed by spin-flip

Ethnobotanical notes from Daniel Rolander's Diarium Surinamicum (1754-1756): Are these plants still used in Suriname today?

The recent English translation of the diary of the Swedish naturalist Daniel Rolander (written 1754-1756) reveals the earliest records on useful plants of Suriname. Since he did not grant Linnaeus access to his specimens, Rolander never received credit for his work, part of his collection was lost, and his diary never published. Here we compare Rolander's notes with recent ethnobotanical data from

Transverse momentum dependence of eta meson suppression in Au plus Au collisions at root s(NN)=200 GeV

New measurements by the PHENIX experiment at the Relativistic Heavy Ion Collider for. production at midrapidity as a function of transverse momentum ((PT)) and collision centrality in root s(NN) = 200 GeV Au + Au and p + p collisions are presented. They indicate nuclear modification factors (R-AA) which are similar in both magnitude and trend to those found in earlier pi(0) measurements. Linear fi

Diagnostic accuracy of 3D color volume-rendered CT images for peroneal tendon dislocation in patients with acute calcaneal fractures

Background: Use of three-dimensional (3D) color volume-rendered (VR) images has been reported to be more time-efficient compared to that of cross-sectional computed tomography (CT) images for the diagnosis of peroneal tendon dislocation. However, the diagnostic performance of this technique has not been studied. Purpose: To test diagnostic accuracy of 3D color VR CT images of ankle for peroneal te

Time-resolved investigation of nanometer scale deformations induced by a high flux x-ray beam

We present results of a time-resolved pump-probe experiment where a Si sample was exposed to an intense 15 keV beam and its surface monitored by measuring the wavefront deformation of a reflected optical laser probe beam. By reconstructing and back propagating the wavefront, the deformed surface can be retrieved for each time step. The dynamics of the heat bump, build-up and relaxation, is followe

A numerical model of beach morphological evolution due to waves and currents in the vicinity of coastal structures

A numerical model was developed of beach morphological evolution in the vicinity of coastal structures. The model includes five sub-models for random wave transformation, surface roller development, nearshore wave-induced currents, sediment transport, and morphological evolution. The model was validated using high-quality data sets obtained during experiments with a T-head groin and a detached bre

Operation for nitritation of sludge liquor in a full-scale SBR.

At Sjölunda WWTP, a full-scale SBR for treatment of mesophilic sludge digester liquor has been operated almost a year with stable nitrite accumulation. Only nitritation of the sludge liquor is needed since the oxidized ammonium is denitrified in the first anoxic zone of the high-loaded activated sludge in the main plant. The process strategy was to have an ammonium set-point to end the aeration, a

Bioturbation as Driver of Zooplankton Recruitment, Biodiversity and Community Composition in Aquatic Ecosystems

In an experimental study we assessed if benthic bioturbating invertebrates affect the recruitment (hatching) of zooplankton from the sediment, and if this effect persists as differences in the zooplankton community in the water column, that is, if bioturbation quantitatively stimulates benthic-pelagic coupling. We investigated the effects of four different benthic invertebrates (Asellus aquaticus,

beta-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices

Background: Inflammation acting in synergy with brain ischemia aggravates perinatal ischemic brain damage. The sensitizing effect of pro-inflammatory exposure prior to hypoxia is dependent on signaling by TNF-alpha through TNF receptor (TNFR) 1. Adrenoceptor (AR) activation is known to modulate the immune response and synaptic transmission. The possible protective effect of (alpha) over tilde and

Låt studenterna orchestrera sitt eget lärande- Det kollaborativa lärandet genom öppna digitala resurser (OER)

Ebba Ossiannilsson Lunds universitet Alastair Creelman, Linnéuniversitetet OER, MOOC, spelifiering och badgerörelsen Det är bara några av de trender vi har sett under 2012, mer kommer det att bli framöver och fort går det runt om i världen. I Horizon rapporten för 2012 förutsågs detta, men även augmented learning, individualiserat lärande, kursdesign och examination för lärande, sociala medier, le

Connecting Spatially Coupled LDPC Code Chains

Codes constructed from connected spatially coupled low-density parity-check code (SC-LDPCC) chains are proposed and analyzed. It is demonstrated that connecting coupled chains results in improved iterative decoding performance. The constructed protograph ensembles have better iterative decoding thresholds compared to an individual SC-LDPCC chain and require less computational complexity per bit wh

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

The genetic networks controlling stem cell identity are the focus of intense interest, due to their obvious therapeutic potential as well as exceptional relevance to models of early development. Genome-wide mapping of transcriptional networks in mouse embryonic stem cells (mESCs) reveals that many endogenous noncoding RNA molecules, including long noncoding RNAs (lncRNAs), may play a role in contr

Samtidshermeneutik. Sociologiska optioner, predikament, realiteter

Artikeln diskuterar moderniteten, samtiden, sociologin och förhållandet dem emellan samt hur samtiden betingar vetandet om denna samtid, och hur vetandet om samtiden gestaltas. Den epistemologiska konstellation som framkallas förstår jag som sociologisk samtidshermeneutik, eller samtidshermeneutisk sociologi. Dess grundantagande är: ju mer en kultur karakteriseras av kontingens (komplexitet, trans

Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years

OBJECTIVE- We studied differences between patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes, and classical type 1 diabetes diagnosed after age 35 years. RESEARCH DESIGN AND METHODS- Polymorphisms in HLA-DQB1, INS, PTPN22, and CTLA4 were genotyped in patients with LADA (n = 213), type 1 diabetes diagnosed at >35 years of age (T1D(>35y); n = 257) or <20 years of age (T1D(<20