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Mantle cell lymphoma (MCL) with Myc aberrations has previously been shown to be associated with poor survival and worse response to current treatment strategies. This study aims to investigate the association between Myc overexpression and clinical outcome and to identify drugs targeting MCL with Myc alterations. Data from the two patient cohorts BLISS and N-MCL2/3 was analyzed, and the associatio
Plantera skog i hagen eller på vetefältet? Att börja använda marken i stor skala i form av jordbruk, städer och nedhuggning av skog var en förutsättning till att den mänskliga civilisationen skulle uppstå, men det har inte kommit utan konsekvenser för planeten. Att använda marken på ett hållbart sätt är avgörande för att bemöta de stora miljöproblemen i världen som klimatförändringar och förlustenThe environmental effects, not least on biodiversity, of land use and land use change provide major challenges when sustainability goals are to be met along with demand for production and other ecosystem services. Here I systematically review literature on one major land use change, from agriculture to forest, and the implications for biodiversity. The aim is to provide information for land use de
Online dating is growing rapidly within society. In the light of the covid-19 pandemic, the popular online dating app Tinder provides a new social setting for dating and romantic relationships. There is some debate whether online dating apps liquify (devolves) love - as proposed by Zygmunt Bauman - or make dating more accessible and efficient. This thesis aims to understand and create knowledge of
Title: “With Great Freedom Comes Great Responsibility” - A Qualitative Study of Managers’ and Their Respective Employees’ Experiences of Mandatory Remote Work and Relationships in this Work Setting Authors: Anna Rebeka Dinnyes & Siri McGarvey Supervisor: Monika Müller, Lund University, Sweden Examiner: Stefan Sveningsson, Lund University, Sweden Course: BUSN49, Degree Project in Master’s P
This thesis investigates the quantization of field theories using the functional integral formalism. Gauge invariance necessitates a gauge-fixing procedure that chooses a unique field configuration from each gauge orbit. Faddeev and Popov suggested an adjustment to the action that implements gauge fixing in this framework, however it has been found that this procedure fails to uniquely fix the gau
Vi har testat en av teorierna för kvanttermodynamik med Hubbard-Holstein modellen på en dimer. Resultaten visar att effekten av fjädern är att utjämna de typiska kännetecknen i arbetet utfört av systemet. Vi har sett att systemet kan agera som ett batteri som kan laddas. Vi såg också att det var viktigt vilken ordning vi ändrade parametrarna i systemet, som vi förväntade oss av klassisk termodynamThe goal of this project is to characterize the quantum thermodynamics of a Hubbard-Holstein dimer. We explore how the standard formalism of quantum thermodynamics behaves in the context many-body physics. To this end, the simplest possible lattice model which includes electron and electron-phonon interactions is used, namely the Hubbard-Holstein dimer. The system is time evolved using exact diago
Syfte: Undersöka om det går att utläsa någon variation i företags goodwillnedskrivning år 2019 och 2020 då åren har präglats av både en låg- och högkonjunktur. Metod: Studien har genomförts med en utvärderingsmetodik och kvantitativ metod. Datainsamlingen består utav företags årsredovisningar där utvalda poster har använts för analyskapitlet. Teoretiska perspektiv: Referensramen består av tidigaPurpose: Examine whether there is a difference in companies’ impairment of goodwill in the years 2019 and 2020 as the years have been characterized by both a recession and an economic boom. Methodology: This study has implemented an evaluative approach with the aid of quantitative method. The data was collected from annual reports where selected entries have been used in the analysis chapter. Th
Swedish youth-centres are characterized by their vision of being a “meeting place for all”. To fulfil this vision, inclusion has become a relevant concept and tool for those working within these centres. This thesis is based on interviews with seven youth-workers and managers within youth-centres in a large Swedish municipality. The aim of the study is to investigate how youth-workers and managers
Antal fordon i trafiken börjar bli allt fler och fler. Detta leder till att vägar behöver underhållas emellanåt. För att åtgärda vägarna så krävs det vägarbetare på plats, 90% av dessa vägarbetare känner oro dagligen på sitt jobb. Anledningen till deras oro är att många trafikanter inte tar någon hänsyn till vägarbetare, de kör aggressivt, hänsynslöst och över hastighetsgränsen. Under åren 2003-20The number of vehicles in traffic is increasing. This means that roads need to be maintained regularly. To repair the roads, road workers are required on site. Ninety percent of these road workers feel anxious daily at their work. The reason for their concern is that many road users do not pay any attention to road workers, they drive aggressively, ruthlessly and over the speed limit. During the y
Over the last decades, the Swedish insurance industry has seen decreased entry barriers due to deregulation and emerging new technologies, which have the potential to disturb the stagnated and consolidated competitive landscape of the industry. Initiated by newcomers like American insurance startup Lemonade, and later Swedish Hedvig among others, there is an increased push toward digitalization, t
Type 2 Diabetes Mellitus (T2DM) have known to be one of the most common degenerative diseases which highly correlate with lifestyle, including consumption habits. It cannot be denied that the availability and accessibility to high processed food, high in carbohydrates play an important role on increasing the risk of T2DM. On the contrary, consumers’ awareness towards health and nutrition are also
Abstrakt Denna kvalitativa studie har haft till syfte att undersöka hur tolv människors sociala privat- och yrkesliv har påverkats under coronapandemin. Intervjupersonerna är i samma ålder och har hemmavarande barn i skolåldern. Datainsamlingen gjordes via personliga intervjuer, främst via Teams eller telefon, under perioden 10 februari 2021 till 17 februari 2021. Teoretiska utgångspunkter hämtas
Detta examensarbetet handlar om att forma en hemisfäroid från en platt honeycomb-skiva samtidigt som honeycomb-strukturen bibehålls. Honeycomb-strukturen är ett hexagonalt mönster som kan vara gjord av hexagoner, cirklar eller trianglar. Inom kartografi görs jordens sfäriska yta om till en platt representation i form av en karta. Omvandlingen är omöjlig utan förvrängning eller uppdelning i mindreThis Master thesis is about forming a hemispheroid out of a flat honeycomb while retaining the honeycomb structure through an even spread of deformation. The honeycomb structure is a hexagonal structure which can be made out of hexagons, circles or triangles. In cartography the surface of the earth, a spheroid, must be distorted or cut up in order to create a flat map. In the same way forming of
Syftet med uppsatsen är att undersöka och visa utvecklingen av Yahya Hassans författarskap samt vilka nyckelpersoner som deltog i hans etableringsprocess. Genom att göra studier om hur en författare utvecklas ger både författare och förlag kunskap om hur de själva kan påverka och styra sin position på det litterära fältet. Metoden för uppsatsen har varit kvalitativ forskning och ett stort materia
The framework for isogeometric analysis (IGA) is presented, especially the construction and use of non-uniform rational B-splines (NURBS) to represent geometry, and a method utilizing IGA for structural optimization both for linear elastic and non-linear elastic deformations is implemented. Topology optimization of a linear elastic cantilever is performed, showing that IGA is inecient for topology
Det här arbetet går ut på att jämföra säkerhet och trygghet för cyklister på tre olika korsningar i Helsingborg. Helsingborg stad är en snabbt växande stad som har svårt att få fler att börja cykla. För att utveckla en stad så att fler börjar cykla är det viktigt att få cyklister att känna sig trygga. Utformningar av korsningar i städer fokuserar mycket på att säkerheten ska prioriteras. Det lederThis thesis involves comparing safety and the feeling of safety at three different intersections in Helsingborg. Helsingborg municipality is a fast-growing city that has difficulties getting more people to start cycling. In order to develop a city so more people start cycling, it is important to make cyclists feel safe. Designs of intersections in cities focus a lot on prioritizing safety. This me
Autoimmune diseases are complex and characterized by the loss of self-tolerance to self-antigens, leading to an immune attack on target tissues of the body. Psoriasis (Ps) and psoriasis arthritis (PsA) are poorly understood autoimmune diseases with unknown genetic and environmental sources. It has been previously demonstrated that a single intra peritoneal injection of mannan induces an acute infl
Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignancy which poses a challenge for treatment efficiency. To better stratify DLBCL patients and optimize treatment protocols, we analyzed the serum proteome using samples from a population-based cohort of DLBCL patients. Our objective was to find association between serum protein expression with clinical parameters such as overall
Dynamically predicted shelf-life label (DPSL) has been discussed to be one of the solutions to curb meat waste. Therefore, the research about the DPSL label and the perceptible information obtained by minced meat consumers is conducted. The research purpose is to identify the critical factors to design a DPSL label for minced meat consumers, and to design and assess the label with the consumers. T
