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Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia

Popular Abstract in Swedish Glukos (druvsocker) är den primära energikällan för människan. Därför är det viktigt att effektivt kunna lagra extra socker från blodcirkulationen efter måltider, och att snabbt kunna använda det upplagrade sockret mellan måltiderna. Glykogen är upplagringsformen av socker i cellerna och en glykogenmolekyl kan bestå av tiotusentals glukosmolekyler. Glykogensyntesen reglEffective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. The present studies were undertaken to isolate and c

Stochastic Reactor Models for Engine Simulations

The aim of the thesis work is the further development of practical engine simulation tools based on Stochastic Reactor Models, SRMs. Novel and efficient implementations were made of a variety of SRMs adapted to different engine types. The models in question are the HCCI-SRM, the TwoZone SI-SRM and the DI-SRM. The specific models developed were incorporated into two different interfaces: DARS-ESSA,

Characterization of nontypeable Haemophilus influenzae innate interactions with human cells

Non-typeable Haemophilus influenzae (NTHi) is a human pathogen causing diseases in the upper and lower respiratory tract. Otitis media-prone children and adults with cystic fibrosis or chronic obstructive pulmonary disease, are repeatedly infected by NTHi Research in recent years brought to light the entry and survival of NTHi in epithelial cells and macrophages. Their internalization could be a

User related assessment of Enhanced Dynamic Pass Predictor (BMW)

The aim of the user related assessment was to study perceived advantages, disadvantages, usefulness, trust, acceptance, willingness to have and pay for the driver assistance system: Enhanced Dynamic Pass Predictor developed by BMW within the framework of the SECONDS subproject. Due to restrictions of driving by naïve drivers in real traffic conditions, assessment activities were limited to a demon

A European roadmap for ageing and the environment.

The core of the research theme ageing and the environment is the better understanding of the interrelations between ageing persons and their physical-social surroundings (home environments; out-of-home environments; technology and products) including intervention and implementation.

Aviculture : A History

This book discusses the history of aviculture and the cultural extent of keeping and raising birds in captivity for pleasure, companion, ornamental reasons, religious causes or various economic or practical purposes. Since the dawn of mankind, humans have kept birds in captivity. Several species are truly domesticated, while others have simply been bred in captivity for many generations. Today bir

Event-based time intervals in an Amazonian culture

We report an ethnographic and field-experiment-based study of time intervals in Amondawa, a Tupi language and culture of Amazonia. We analyse two Amondawa time interval systems based on natural environmental events (seasons and days), as well as the Amondawa system for categorising lifespan time (“age”). Amondawa time intervals are exclusively event-based, as opposed to time-based (i.e. they are b

Characteristics of Aerosols Containing Chromium and Nickel From Some Thermal Spraying Operations

Characterization of aerosols, emitted from five methods of thermal spraying with materials containing chromium and nickel were carried out. The characterization procedure includes the determinations of the metal content, the particle size distribution, the oxidation state of chromium and a measure of the solubility of chromium. Three different kinds of samplers and the analytical methods PIXE (Par

Throughput analysis of strongly interfering slow frequency-hopping wireless networks

We derive an approximation for the throughput of strongly interfering frequency-hopping wireless networks, where packet collisions always result in lost data. A system is defined to consist of a certain number of radio networks, each with an arbitrary number of communicating units, coordinated to communicate without interference. Using the approximation, we estimate upper and lower bounds on syste

Subjective prerequisites for the construction of an objective world

Starting with the assumption that perception is not merely a reaction to outside stimulation but a process of creation, although mostly brief and inaccessible to conscious retrieval, the present paper attempts to determine the prerequisites of a stable and secure accout of reality. The authors’ leading hypothesis is that a dependable end product of adaptive and constructive processes is contingent

Amphiphilic Polymers as Additives in Biomedical Polyurethanes. Surface Properties and Morphology

Popular Abstract in Swedish Människor har i alla tider försökt reparera och ersätta skadade vävnader i kroppen. Förr användes naturliga material som t. ex. bomull, silke, tagel och läder. Under 1900-talet har flera syntetiska (konstgjorda) material utvecklats, framförallt olika typer av polymerer (plaster), för användning som ersättning av skadade kroppsvävnader. Beroende på vilken typ av vävnad sThe aim of this work was to achieve surface modification of two biomedical polyurethanes and one poly(urethane urea) through the addition of small amounts of amphiphilic copolymers in solution. The matrix polymers used were the poly(ether urethane)s Pellethane 2363-80AE (P80) and 2363-75D (P75) and a poly(ether urethane urea) similar to Biomer (PUUR). The amphiphilic additives consisted of segment