The function of the efflux pump P-glycoprotein (Pgp) and ABCB1 single nucleotide polymorphisms (SNPs) should be considered as important tools to deepen knowledge of drug nephrotoxicity and disposition mechanisms. The aim of this study is to investigate the association of C3435T, G2677T, C1236T, and T129C ABCB1 SNPs with Pgp activity and exposure to different immunosuppressive drugs in renal transp

Abstract—Rhythmic movement of the arms while walking is an important feature of human gait. In this paper, we present an approach to analyze the movements of the arms while walking by using three wearable wireless devices placed around the torso. One of the devices is transmitter placed at the back and the other two are symmetrically placed receivers that record the power variation due to movement

There is a debate about the date of the Minoan eruption of Santorini as reconstructed from a branch of an olive tree that was buried alive in trephra on Santorini2 and the dating of an ice core horizon attributed to this eruption.3 The olive branch was 14C-wiggle matched to the 14C calibration curve and yielded an age range of 1627-1600 bc4 while the counting of annual layers in the Greenland ice

Aims. This work reports oscillator strengths for transitions of astrophysical interest in singly ionized rhodium. Methods. Seventeen radiative lifetimes in Rh+ have been measured with the time-resolved laser-induced fluorescence technique and combined with theoretical branching fractions calculated using a relativistic Hartree-Fock model including core-polarization effects to obtain oscillator str

Agricultural intensification is recognised as a major driver of biodiversity loss in human-modified landscapes. Several agro-environmental measures at different spatial scales have been suggested to mitigate the negative impact of intensification on biodiversity and ecosystem services. The effect of these measures on the functional structure of service-providing communities remains, however, large

In the study presented in this paper a single-cylinder Scania D12 diesel engine has been converted to work as a pneumatic hybrid. During pneumatic hybrid operation, the engine can be used as a 2-stroke compressor for generation of compressed air during vehicle deceleration and during vehicle acceleration the engine can be operated as an air-motor driven by the previously stored pressurized air. T

Consideration of strut inertia can have significant influence on the modal behavior of a Gough-Stewart Platform (GSP). However, in the literature, the strut inertia has not yet been taken into account in its vibration study with a parametric approach. In this paper, we present a fully parametric approach to formulate the damped vibrations of GSPs taking into account the strut masses and moments of

This study investigates online material published in reaction to a Science magazine report showing the absence of peer-review and editorial processes in a set of fee-charging open access journals in Biology. Quantitative and qualitative textual analyses are combined to map conceptual relations in these reactions; and to explore how understandings of scholarly communication and publishing relate to

Mathias Strandberg’s doctoral thesis De sammansatta ordens accentuering i Skåne- målen (‘Tonal Word Accent and Stress in Compound Words in Traditional Scanian Dialects’) deals with the prosodic system of the dialects of Skåne in southern Swe- den. These dialects have two prosodic features that diverge from the situation in Standard Swedish. Both the dialects and the standard language have two tona

We report the first measurement of the near oxygen K-edge auger spectrum of the glycine molecule. Our work employed an x-ray free electron laser as the photon source operated with input photon energies tunable between 527 and 547 eV. Complete electron spectra were recorded at each photon energy in the tuning range, revealing resonant and non-resonant auger structures. Finally ab initio theoretical

Use of computational fluid dynamics (CFD) software packages within fire performance based engineering and risk assessment is increasing substantially. An important part in the process is validation and verification in order to be able to assess the accuracy and reliability of the computational tools. To improve the credibility of using CFD modeling in several high-consequence fields, such as the n

The high Q-factor (low bandwidth) and low efficiency make the design of small antennas challenging. Here, convex optimization is used to determine current distributions that provide upper bounds on the antenna performance. Optimization formulations for maximal gain Q-factor quotient, minimal Q-factor for superdirectivity, and minimum Q for given far-fields are presented. The effects of antennas em

Popular Abstract in Swedish Det svenska utbildningsväsendet styrs av nationella styrdokument som skollag, läroplaner och kursplaner. Det demokratiska uppdraget är en central fråga i dessa dokument. Avhandlingens syfte är att undersöka hur pedagogerna hanterar detta demokratiuppdrag och hur de påverkas av sociala krafter på olika nivåer. Demokratibegreppet är öppet för olika tolkningar. Inom utbiThe Swedish education system is governed by national steering documents, like the Education Act, curriculi and syllabuses. The democratic assignment is a central issue in these documents. The thesis aims to investigate how teachers handle this democratic assignment and how they are influenced by forces on different social levels. The concept of democracy is open to many interpretations. Democrac

Mental health disorders are a rapidly growing public health problem. Despite the fact that lack of trust in the health-care system is considered to be an important determinant of health, there is scarcity of empirical evidence demonstrating its associations with health outcomes. This is the first study which aims to evaluate the association between trust in the health-care system and psychological

A fracture risk assessment tool (FRAX (TM)) is developed based on the use of clinical risk factors with or without bone mineral density tests applied to the UK. Introduction The aim of this study was to apply an assessment tool for the prediction of fracture in men and women with the use of clinical risk factors (CRFs) for fracture with and without the use of femoral neck bone mineral density (BMD

Differential cross sections for elastic scattering of photons from the deuteron have recently been measured at the Tagged-Photon Facility at the MAX IV Laboratory in Lund, Sweden. These first new measurements in more than a decade further constrain the isoscalar electromagnetic polarizabilities of the nucleon and provide the first-ever results above 100 MeV, where the sensitivity to the polarizabi