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Quantification of the electrostatic properties of the glomerular filtration barrier modeled as a charged fiber matrix separating anionic from neutral Ficoll

Oberg CM, Rippe B. Quantification of the electrostatic properties of the glomerular filtration barrier modeled as a charged fiber matrix separating anionic from neutral Ficoll. Am J Physiol Renal Physiol 304: F781-F787, 2013. First published January 9, 2013; doi:10.1152/ajprenal.00621.2012.-In the current study we explore the electrostatic interactions on the transport of anionic Ficoll (aFicoll)

Pathophysiology and Potential Treatments of Pulmonary Hypertension due to Systolic Left Heart Failure.

Pulmonary hypertension (PH) due to left heart failure is becoming increasingly prevalent, and is associated with poor outcome. The precise pathophysiological mechanisms behind PH due to left heart failure are, however, still unclear. In its early course, PH is caused by elevated left ventricular filling pressures, without pulmonary vessel abnormalities. Conventional treatment for heart failure may

Continuous separation of cells and particles in microfluidic systems

The progress in microfabrication and lab-on-a-chip technologies has been a major area of development for new approaches to bioanalytics and integrated concepts for cell biology. Fundamental advances in the development of elastomer based microfluidics have been driving factors for making microfluidic technology available to a larger scientific community in the past years. In line with this, microfl

The importance of thermal boundary transitions on glacial geomorphology; mapping of ribbed/hummocky moraine and streamlined terrain from LiDAR, over Småland, South Sweden

In this paper we synthesise previous sedimentological studies and new, high resolution, digital elevation models from southern Småland to investigate the evolution of a deglacial landscape. Starting approximately at the deglacial highest shoreline, there is a 20-40 km wide zone of ribbed and hummocky moraine that can be connected to the predominantly subaqueous Göteborg moraine. North of this ther

Evaluation of a School-Based Program Aimed at Preventing Depressive Symptoms in Adolescents

The aim of this pilot study was to evaluate the implementation of a universal school-based cognitive behavioral program whose target is to prevent depressive symptoms in adolescents. The study had a quasi-experimental design with pretest, posttest, and a 1-year follow-up and provides an illustrative calculation for the implementation costs of the intervention. Sixty-two students (aged 14) and seve

Governing renewable energy in the EU: Confronting a governance dilemma

Promoting renewable energy sources (RES) has been addressed a key strategy for mitigating climate change, the governing in which has turned out a challenging and protracted task for the EU. There is often an implicit assumption that concern for climate change drives energy policy, but a closer look at the development of European RES policy indicates how EU governors have had to confront a range of

Neighborhood walkability, deprivation and incidence of type 2 diabetes: A population-based study on 512,061 Swedish adults.

Neighborhood walkability has been associated with increased physical activity, but only a few studies have explored the association between walkability and health outcomes related to physical activity, such as type 2 diabetes. The aim of this study was to investigate the association between objectively assessed neighborhood walkability and the 4-year incidence of type 2 diabetes in a sample of 512

Receiving Gifts for Sex in Moscow, Kyiv, and Minsk: A Compensated Dating Survey

‘Compensated dating’’ (CD) indicates the exchange of sexual intimacy for material compensation. This article investigates CD as receiving gifts for sex, such as luxuries, rent, travel, or monetary gifts. It proceeds by describing who engages in the practice and why, while comparing Russia with its cultural and linguistic neighbors, Ukraine and Belarus. A survey, which was answered by a representat

Inverse-motion-based form finding for quasi-incompressible finite electroelasticity

This work deals with inverse-motion-based form finding for electroelasticity. The inverse motion problem is formulated for the electroelastic case, and the resulting equations are implemented within a finite element framework. A four-field variational approach is adopted, taking into consideration the typically incompressible behavior of the elastomer materials commonly used in electromechanical a

Meanings Turkish people perceive in everyday occupations: Factor structure of Turkish OVal-pd

Occupational value with predefined items scale is an originally 26-item Swedish tool used to assess values people find in their everyday doings. The present study validated this scale on a Turkish sample and described the values that Turks perceived in their daily doings. The participants included a convenience sample of 446 adults with mean age 26 (SD = 7.3). Initial item analysis followed by pri

The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems-A review.

Poly(d,l-lactic-co-glycolic acid) (PLGA) is the most frequently used biodegradable polymer in the controlled release of encapsulated drugs. Understanding the release mechanisms, as well as which factors that affect drug release, is important in order to be able to modify drug release. Drug release from PLGA-based drug delivery systems is however complex. This review focuses on release mechanisms,

Beta-cell function and metabolic control in Latent Autoimmune Diabetes in Adults with early insulin versus conventional treatment: a 3-year follow-up

Objectives: The optimal treatment of latent autoimmune diabetes in adults (LADA) is not established. We explored whether early insulin treatment, which has shown beneficial effects in rodents and in human pilot studies, would result in better preservation of beta-cell function or metabolic control, compared with conventional treatment. Subjects and methods: Glucagon-stimulated C-peptide and HbAlc

Activating without Inhibiting: Left-Edge Boundary Tones and Syntactic Processing

Right-edge boundary tones have earlier been found to restrict syntactic processing by closing a clause for further integration of incoming words. The role of left-edge intonation, however, has received little attention to date. We show that Swedish left-edge boundary tones selectively facilitate the on-line processing of main clauses, the syntactic structure they are associated with. In spoken Swe

Sensitivity analysis of a cemented hip stem to implant position and cement mantle thickness

Patient-specific finite element models of the implanted proximal femur can be built from pre-operative computed tomography scans and post-operative X-rays. However, estimating three-dimensional positioning from two-dimensional radiographs introduces uncertainty in the implant position. Further, accurately measuring the thin cement mantle and the degree of cement-bone interdigitation from imaging d

A new upper Middle Ordovician-Lower Silurian drillcore standard succession from Borenshult in Ostergotland, southern Sweden: 2. Significance of delta C-13 chemostratigraphy

A total of 239 isotope samples are used for establishing the delta C-13 chemostratigraphy in the upper Middle Ordovician to Lower Silurian succession in the approximately 70 m long Borenshult drillcore. The study interval starts in the upper Darriwilian Furudal Limestone and ends in the Rhuddanian Motala Formation. Four named delta C-13 excursions are recognized in 3-4 formations, namely the Gutte

Organic aerosol components derived from 25 AMS data sets across Europe using a consistent ME-2 based source apportionment approach

Organic aerosols (OA) represent one of the major constituents of submicron particulate matter (PM1) and comprise a huge variety of compounds emitted by different sources. Three intensive measurement field campaigns to investigate the aerosol chemical composition all over Europe were carried out within the framework of the European Integrated Project on Aerosol Cloud Climate and Air Quality Interac