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We describe three cases of community-acquired pneumonia, in which the causative agent was methicillin sensitive S. Aureus positive for Panton-Valentine leukocidin (PVL). The patients were previously healthy children (2 weeks, 12 years and 15 years old). No epidemiologic connection existed, confirmed by spa-typing. Two cases were primary pneumonias with signs of necrosis, and the third case was a p
Rheumatoid arthritis-associated joint pain is frequently observed independent of disease activity, suggesting unidentified pain mechanisms. We demonstrate that antibodies binding to cartilage, specific for collagen type II (CII) or cartilage oligomeric matrix protein (COMP), elicit mechanical hypersensitivity in mice, uncoupled from visual, histological and molecular indications of inflammation. C
Background: The aim of this study was to determine whether lymph node metastasis on pre-treatment 18F-choline PET/CT is an independent prognostic factor for biochemical recurrence (BCR), skeletal metastasis, and cancer specific mortality (CSM), after radical local treatment (radical prostatectomy and/or radiotherapy) in men with high-risk prostate cancer. Medical records were reviewed for men with
The stiffness assessment of the trackbed should include an assessment of ballast, subballast and formation (e.g sub-ballast depth, groundwater profile). Furthermore, a lack of a systematic monitoring brings to the impossibility to produce an effective long term track management system, by allocating budget where emergencies come. Consequently, there is an increasing importance in obtaining a consi
Railway tracks are complex systems, made up numerous critical components such as rails, sleepers/ties, fasteners, ballast, joints, crossings, switches, that require regular monitoring in order to ensure track safety and optimize track efficiency. Many large railways make use of expensive Track Geometry Cars in order to measure railway asset condition through the measurement of rail geometry (gauge
The present paper reports different applications which have a common data source: Automatic Road Analyzer (ARAN) of the Transport Infrastructure Laboratory of the University of Catania. Data surveyed with ARAN were used to develop performance indicators of the road asset. A BIM model makes possible to improve the flexibility in information access and to merge data with the aim to allow a complete
Safety performance functions (SPFs) are crucial to science-based road safety management. Success in developing and applying SPFs, apart data quality and availability, depends fundamentally on two key factors: the validity of the statistical inferences for the available data and on how well the data can be organized into distinct homogeneous entities. The latter aspect plays a key role in the ident
The paper target is to analyze the influence of passing lane section and merging area lengths, which represent a critical part in the geometric design of passing lanes. The lack of observed data and the still limited implementation of short passing 2 + 1 lane in Poland do not allow to perform a reliable performance-based design of their length to balance context and economical restrains with opera
Rail Track performance is highly dependent upon the magnitude and variation of differential track geometry. Consequently, there is an increasing interest in obtaining a consistent measure of trackbed stiffness and track geometry in the physical and time restrictions applicable on live track for assessing potential maintenance requirement and subsequent design of remedial measures. Furthermore, a l
The research presented here evaluated road safety on the road sections included in the Intelligent Traffic Control System of the Podhale Region (ISSRRP) in Poland. This travel time information system consists of a remote traffic microwave sensor, cameras, as well as automatic plate number recognition on national roads with variable message signs and a mobile app to suggest alternative routes in th
The road safety barriers are today designed and installed in compliance with the European standards for Road Restraint Systems (EN 1317), which lays down common requirements for the testing and certification in all EU countries. The introduction of the European Union (EU) regulation for safety barriers, which is based on performance, has encouraged European road agencies to perform an upgrade of t
