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Understanding the mechanical properties of human femora is of great importance for the development of a reliable fracture criterion aimed at assessing fracture risk. Earlier ex vivo studies have been conducted by measuring strains on a limited set of locations using strain gauges. Digital Image Correlation (DIC) could instead be used to reconstruct the full-field strain pattern over the surface of

A highly sensitive flow injection analysis (FIA)-based thermal enzyme-linked immunoassay, TELISA, was developed for the rapid detection of atrazine (ATZ) in tap water. ATZ and beta-lactamase-labeled ATZ were employed in a competitive immunoassay using a monoclonal antibody (mAb). After the off-column liquid-phase competition, the mAb was captured on the Protein G Sepharose (TM) 4 Fast Flow (PGSFF)

Popular Abstract in Swedish Diabetes relaterade fotsår är en vanlig och allvarlig komplikation till diabetes. Orsaken till fotsår är mångfasetterad och inkluderar bland annat diabetesrelaterade nervskador och försämrad funktion i stora och små blodkärl. Vid förekomst av högt blodsocker fungerar immunförsvaret sämre och problematiska infektioner är vanligare vid diabetes. Sårläkning försämras vid lChronic diabetic foot ulcers are a source of major concern for both patients and health care systems. Oxygen deficiency plays a major role in the pathogenesis of these ulcers. Hyperbaric oxygen therapy (HBOT) has been proposed as a medical treatment for diabetic foot ulcers, but the clinical utility has not been established. Hyperbaric Oxygen in Diabetic patients with chronic Foot Ulcer (HODFU) st

This essay discusses the author Sara Stridsberg's revisiting of Valerie Solana's work and anger as a feminist response to the injustice of sexism and homophobia and to envision a future loaded with feminist energy.

Popular Abstract in Swedish Cancer behandlas i första hand med kirurgi, cellgifter och extern strålbehandling. Under senare år har man dessutom utvecklat så kallade målsökande behandlingar, som binder till en viss struktur i tumören. De kan verka på olika sätt: antingen genom att blockera en signal i cellerna och på så vis hindra tumören från att växa, eller genom att stimulera patientens immunförIn radioimmunotherapy, monoclonal antibodies (mAbs) are used as a targeting agent carrying a toxic payload consisting of radionuclides. This treatment allows the irradiation of small lesions, even on the microscopic level. In the present work, two radionuclides with different properties were used. Lutetium-177 (177Lu) is a beta-particle-emitting radionuclide (t½=6.7 days) and astatine-211 (211At)

Calculations of large-scale displacement distances were made to evaluate the combined effect of small-scale movement pattern of a Collembola, Protaphorura armata. The effect of presence of food and conspecific density on turning angle, step length and activity/motility was investigated. Calculations of net square displacement were made both by assuming correlated random walk (CRW) and by resamplin

Westphal's thesis contains a summary of earlier structural analyses of Hebrews. Her own discourse analysis structures Hebrews into three parts 1) 1:1–4:16; 2) 4:11–7:28 and 8:1–10:25; 3) 10:19–13:25. Westphal characterizes Heb 4:11-16 and 10:19-25 as "overlapping" parts and as keys to the structure and meaning of Hebrews. The structure according to this approach is not new. A shortcoming in this t

Actions and events are central to a semantics of natural language. In this article, we present a cognitively based model of these notions. After giving a general presentation of the theory of conceptual spaces, we explain how the analysis of perceptual concepts can be extended to actions and events. First, we argue that action space can be analyzed in the same way as, for example, colour space or

The generation of diversity for directed protein evolution experiments shows an important bottleneck in the in vitro random mutagenesis protocols. Most Of them are biased towards specific changes that eventually confer a predicted and conservative mutational spectrum, limiting the exploration of the vast protein space. The current work describes a simple methodology to in vivo recombine mutant lib

Aim: This thesis serves two purposes. First, it informs specialists in global public health to consider a broader spectrum of pediatric disease. Second, it informs specialists in pediatric hospital care of how the feasibility of their clinical practice depends on a functioning health care system. Methods: The papers contextualize pediatric disease entities that so far have received relatively sp

There are currently several commercially available radiotherapy treatment units without a flattening filter in the beam line. Unflattened photon beams have an energy and lateral fluence distribution that is different from conventional beams and, thus, their attenuation properties differ. As a consequence, for flattening filter free (FFF) beams, the relationship between the beam-quality specifier T

Antisymmetric magneto-resistance anomalies generated by a reversal of the magnetization are studied in a number of GaMnAs/InGaAs layers with out-of-plane (easy axis) magnetization. The anomalies occur independent of the magnetic field orientation. This shows, that once a magnetic domain with reversed magnetization is nucleated, simply the presence of the domain wall between the longitudinal contac

Translating new findings in the laboratory into therapies for patients is a slow and expensive process. The development of therapies for neurodegenerative diseases is further complicated by the difficulty in determining whether the drug truly retards the slow degenerative process or provides only symptomatic benefit. In this issue, Aviles-Olmos et al. describe a first in Parkinson's disease (PD) p

Background: The involvement of aquaporin (AQP) water and small solute channels in the etiology of several diseases, including cancer, neuromyelitis optica and body fluid imbalance disorders, has been suggested previously. Furthermore, results obtained in a mouse model suggested that AQP9 function contributes to hyperglycemia in type-2 diabetes. In addition, the physiological role of several AQP fa