Novel insights of intracellular complement in pancreatic β-cell physiology
The complement system is a link between adaptive and innate immunity, which is a first line protection against pathogens. It can be activated through three different pathways which all lead to formation of C3 and C5 convertases and final complement-mediated lysis of cells. The system contains regulatory mechanisms at different steps of activation to avoid lysing of own cells. Recent years, have sh
