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Competition enhances spatial genetic differentiation

Questions: How does the number of species in a community affect the level of genetic diversity of its constituent species? What is the relation between competitive interactions and the spatial distribution of genetic variation? When spatially structured, how is the genetic differentiation among subpopulations affected by competition and size of the community? Model features and key assumptions: A

Retrofitting of reinforced concrete beams using composite laminates

This paper presents the results of an experimental study to investigate the behaviour of structurally damaged full-scale reinforced concrete beams retrofitted with CFRP laminates in shear or in flexure. The main variables considered were the internal reinforcement ratio, position of retrofitting and the length of CFRP. The experimental results, generally, indicate that beams retrofitted in shear a

Comparison of Cis- and Oxaliplatin-induced Destabilization of 15-mer DNA- and RNA Duplexes by Binding to Centrally Located GG- and GNG Sequences

Thermodynamic parameters are presented here illustrating the effects caused by the two anticancer active metal complexes cisplatin and oxaliplatin after introduction into four closely related RNA and DNA duplexes. The duplexes used are blunt end, fully complementary 15-mer duplexes with a centrally located either GG- or GNG (here: N = T or U) binding site. For all duplexes, a common trend of reduc

Ductus venosus blood flow velocity waveform in diabetic pregnancies

Objective Maternal diabetes during pregnancy is associated with congenital cardiac malformations and hypertrophic cardiomyopathy. Blood flow in the ductus venosus (DV) has been postulated to reflect cardiac function. The aim of our study was to investigate if diabetic pregnancies exhibit abnormal DV hemodynamics, hence indicating changes in fetal cardiac function. Methods The pulsatility index of

Cell periphery-related proteins as major genomic targets behind the adaptive evolution of an industrial Saccharomyces cerevisiae strain to combined heat and hydrolysate stress

Background: Laboratory evolution is an important tool for developing robust yeast strains for bioethanol production since the biological basis behind combined tolerance requires complex alterations whose proper regulation is difficult to achieve by rational metabolic engineering. Previously, we reported on the evolved industrial Saccharomyces cerevisiae strain ISO12 that had acquired improved tole

Collective and noncollective excitations in Te-122

High-spin states in Te-122 were populated in the reaction Se-82(Ca-48, alpha 4n) Te-122 at a beam energy of 200 MeV and gamma-ray coincidences weremeasured with the Gammasphere spectrometer. The previously known level scheme was extended to considerably higher spin. Maximally aligned states and several high-energy transitions feeding into some of these levels were observed. In addition, seven coll

Factors associated with young children’s self-perceived physical competence and self-reported physical activity.

The aim of this study was to identify factors associated with self-reported physical activity (PA), self-perceived physical fitness and competence in physical education (PE) among young children. The study included physical tests, anthropometric measures and a questionnaire. The study group comprised 206 children (114 boys and 92 girls, aged 8–12 years). Positive Odds Ratio was used in the logisti

Comparison of cisplatin sensitivity and the 18F fluoro-2-deoxy 2 glucose uptake with proliferation parameters and gene expression in squamous cell carcinoma cell lines of the head and neck

Background: The survival of patients with locally advanced head and neck cancer is still poor, with 5-year survival rates of 24-35%. The identification of prognostic and predictive markers at the molecular and cellular level could make it possible to find new therapeutic targets and provide "taylor made" treatments. Established cell lines of human squamous cell carcinoma (HNSCC) are valuable model

PHENIX measurements of 3D emission source function in Au-Au collisions at sqrt(s) = 200 GeV

A state-of-the-art 3D source imaging technique is used to extract the 3D two-pion source function in central and mid-central Au+Au collisions at GeV. The source function indicates a previously unresolved non-Gaussian tail in the directions of the pion pair transverse momentum (out) and along the beam (long). Model comparisons give robust estimates for several characteristics of the emission source

Evaluating Amyloid-beta Oligomers in Cerebrospinal Fluid as a Biomarker for Alzheimer's Disease

The current study evaluated amyloid-beta oligomers (A beta o) in cerebrospinal fluid as a clinical biomarker for Alzheimer's disease (AD). We developed a highly sensitive A beta o ELISA using the same N-terminal monoclonal antibody (82E1) for capture and detection. CSF samples from patients with AD, mild cognitive impairment (MCI), and healthy controls were examined. The assay was specific for oli

Experimental investigation on the effect of detail design on wood moisture content in outdoor above ground applications

An essential part of a performance-based service life design format for wood exposed in outdoor applications is the effect of proper detailing in terms of avoiding moisture traps. Models for predicting degradation and non-performance caused by decay are functions of arbitrary climate history of combined moisture content and temperature. Therefore it is crucial to be able to predict the behaviour o

Gene expression studies of pregastrulation development: the basement membrane is essential for cell differentiation

Basement membranes (BMs) are sheet-like structures of extracellular matrix. They act as a supporting structure but can also significantly influence cellular behavior in development, tissue homeostasis and disease. Laminins, a major BM component, are multidomain proteins, consisting of three polypeptide chains (α, β and γ). During pregastrulation development, stem cells convert and epithelial tissu

Associations between proteins and heavy metals in urine at low environmental exposures: Evidence of reverse causality

Heavy metals can cause renal effects on vulnerable populations but it is uncertain whether these metals still pose health risks at the low exposure levels now prevailing in most industrialized countries. In a cross-sectional study performed on 736 adolescents, we assessed the associations between the concentrations of cadmium and lead in blood and urine and the urinary concentrations of albumin an

Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

Sera from 25 metastatic breast cancer patients and 25 healthy controls were subjected to affinity chromatography using immobilized galectin-1. Serum from the healthy subjects contained on average 1.2 mg per ml (range 0.7-2.2) galectin-1 binding glycoproteins, whereas serum from the breast cancer patients contained on average 2.2 mg/ml (range 0.8-3.9), with a higher average for large primary tumour

Storfjärilar som ökar sin utbredning: nytillskotten i storfjärilsfaunan i sydligaste Sverige under perioden 1973-2009

This study highlights the expansion of butterflies and macromoths occurring in southern Sweden. Recent changes in climate and habitat has been stressed as the main factors influencing changes in species distributions. Climate change implies an increase in temperature and some species are assumed to extend their northern ranges. In this study we compiled information about the first observations of

Att lära, att göra, att klara: Förmedling av datortekniska hjälpmedel till barn medsynnedsättning. Från förskrivning till vardaglig användning iskola och hem

Förmåga att använda informations- och kommunikationsteknik framhålls numera ofta som en förutsättning för delaktighet på lika villkor i samhällslivet. Nära förknippat med detta är de insatser som görs för att överbrygga digitala klyftor i samhället. IKT har gjort deltagandet i samhällslivet mer möjligt för personer med synnedsättning. Tillgång till teknik innebär dock inte alltid att den kan använ

Carbon routes from decomposing plant residues and living roots into soil food webs assessed with C-13 labelling

This field experiment investigated how C from fresh organic amendments and from a growing leek crop was allocated into different soil microbial and faunal groups in an arable field. A C-13-enriched red clover green manure was incorporated in one treatment, while the growing leek crop was pulse labelled with (CO2)-C-13 in another. Incorporation of C-13 into microbial fatty acids, micro- and macroar