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En stor svensk tvillingstudie visar att den som insjuknar i diabetes före 65 års ålder löper avsevärt större risk att drabbas av vaskulär demens eller Alzheimers sjukdom. Forskargrupper vid Karolinska institutet i Stockholm, universitetet i Göteborg och University of California i Los Angeles har analyserat data från en stora svensk tvillingstudie för att undersöka sambandet mellan diabetes och ris

https://www.diabetesportalen.lu.se/artikel/diabetes-dubblar-risken-demenssjukdom - 2025-10-05

En gemensam inflammationsfaktor tycks ligga bakom den fortgående förstörelsen av insulinproducerande betaceller vid såväl typ 1 som vid typ 2 diabetes. Upptäckten kan bana väg för behandling som hejdar eller bromsar förloppet. I de insulinbildande betacellerna från diabetespatienter finns det mer än 30 gånger mer av en inflammationsfaktor, CXCL10, jämfört med hos icke-diabetiker. Förekomsten av de

https://www.diabetesportalen.lu.se/artikel/samma-bakgrund-till-celldod-vid-typ-1-och-typ-2-diabetes - 2025-10-05

GAD-vaccinet, som tros hejda nedbrytningen av de insulinbildande betacellerna, ska nu prövas tillsammans med läkemedel som tros stimulera tillväxt av nya betaceller. Vuxna typ 1 diabetiker ska testa kombinationen. - Vi är mycket entusiastiska över denna studie som ska undersöka om kombinationen förmår kan förbättra behandlingen av typ 1-diabetes", säger professor David Harlan i ett pressmeddelande

https://www.diabetesportalen.lu.se/artikel/gad-plus-medel-som-stimulerar-betacellerna-ska-testas - 2025-10-05

Tidigare studier har visat att högt blodsocker leder till åderförkalkning, vilket i sin tur leder till hjärt-kärlsjukdomar. Vanlig kanel har visat sig sänka blodsockret. Kan det vara en lösning? Försämrade matvanor runt om i världen leder till en ökning av kroniska sjukdomar som typ 2-diabetes och hjärt-kärlsjukdomar. I dagens välfärdsländer är typ 2-diabetes, övervikt och hjärt-kärlsjukdomar ett

https://www.diabetesportalen.lu.se/artikel/hog-dos-kanel-sanker-blodsockret - 2025-10-05

Med upptäckten av de nya riskgenerna för hjärtinfarkt är nu nio varianter kända. Att ärftligheten har stor betydelse för hjärtinfarkt är en gammal iakttagelse men kartläggningen av riskgener går ett steg vidare. De lägger grunden för en ökad förståelse för de grundläggande mekanismerna bakom och detta i sin tur banar väg för effektivare behandlingar. - Styrkan hos de här nio kända genvarianterna ä

https://www.diabetesportalen.lu.se/artikel/nya-riskgener-hjartinfarkt-identifierade - 2025-10-05

Metformin är världens mest använda läkemedel vid typ 2 diabetes. Medlet är effektivt och biverkningarna få. Nu har forskare i Malmö/Lund utvecklat en analysmetod som undanröjer det största hindret för att än fler patienter ska kunna ta metformin. - Har patienten nedsatt njurfunktion kan metformin i sällsynta fall ackumuleras i kroppen vilket leder till möjlksyraförgiftning, ett livshotande tillstå

https://www.diabetesportalen.lu.se/artikel/ny-analysmetod-sakrar-effektiv-behandling - 2025-10-05

Marcella Birtele will be defending her PhD thesis titled “Functional and Transcriptional Studies of Human Dopaminergic Neurons” on Friday 2nd October. Researching within the Developmental and Regenerative Neurobiology group led by Prof. Malin Parmar, here Marcella tells us about her PhD studies at Lund Stem Cell Center. What has been the research focus of your PhD?Although the projects that I have

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-marcella-birtele - 2025-10-05

With two articles published in quick succession from his time as a research fellow at Cambridge University, UK, Christopher Douse has moved to Lund Stem Cell Center to develop a research programme on newly-discovered guardians of the human genome. More than half of the human genome consists of transposons, DNA sequences that can ‘jump’ around within the genome. Left unchecked these elements can ca

https://www.stemcellcenter.lu.se/article/hush-and-morc2-new-players-transposon-regulation-during-human-development - 2025-10-05

Every year the Swedish Society for Medical Research awards funding to promising young medical researchers. Grant recipients are funded for four years of full- or part-time research, with the aim of establishing an independent scientific career. At this year's call, 203 applications were assessed, of which eight were approved. Isaac Canals from Lund Stem Cell Center is one of this year's grant reci

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-researcher-awarded-ssmf-large-grant - 2025-10-05

In a collaborative study, researchers from Lund Stem Cell Center and University College London have developed a novel method of isolating ‘young’ stem cells still present in old mice. They show that activity of mitochondria, the power generators of the cell, is a stronger indicator of stem cell fitness than age and is a potential therapeutic target for the treatment of age associated disease. The

https://www.stemcellcenter.lu.se/article/novel-approach-identifies-young-stem-cells-old-mice - 2025-10-05

Thank you to all who submitted their entries to Lund Stem Cell Center image competition 2020. Now it’s time to choose a winner! Over the past six months, researchers from Lund Stem Cell Center have been submitting images of their research and work environment to the image competition.Now it's time to pick a winner and, due to the current coronavirus restrictions, we will be deciding on the winning

https://www.stemcellcenter.lu.se/article/lund-scc-image-competition-time-cast-your-vote-0 - 2025-10-05

Congratulations to Lund Stem Cell Center researchers Nicholas Leigh, Karolina Pircs, Isabella Artner and Zaal Kokaia on being awarded funding from the Swedish Research Council – Vetenskapsrådet. Wallenberg research fellow Nicholas Leigh has been awarded the prestigious and highly competitive Vetenskapsrådet starting grant. Nicholas recently started up his lab at Lund University, with the focus of

https://www.stemcellcenter.lu.se/article/vetenskapsradet-awards-lund-stem-cell-center-researchers-over-23-million-sek - 2025-10-05

Stefan Karlsson has been active as a researcher at Lund University for 25 years and during that time has received many major grants and awards. However, never a gold medal. - It feels like a very great honor because the medal is only awarded every nine years for medical research efforts, says Stefan Karlsson The Royal Physiographic Society will be awarding the commemorative medal to Stefan Karlsso

https://www.stemcellcenter.lu.se/article/professor-stefan-karlsson-awarded-gold-medal-research-efforts - 2025-10-05

Nine researchers from Lund Stem Cell Center have been awarded a total of over 29 million SEK in project grants and continued support from the Swedish Cancer Society, Cancerfonden. Congratulations to all researchers from Lund Stem Cell Center awarded support from Cancerfonden! Researchers awarded project grants include: Henrik Ahlenius - ‘Modeling and intervention in glioma using stem cells, reprog

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-researchers-awarded-funding-cancerfonden - 2025-10-05

Zaal Kokaia, professor of neurology at the Department of Clinical Sciences in Lund and former chairman of Lund Stem Cell Center, is this year's winner of the Bengt Falck Prize in Neuroscience. He receives the award for his many years of research on stroke, presented to him by the Dean of the Faculty of Medicine, Erik Renström. How does it feel to receive Bengt Falck's award? - When I arrived in Lu

https://www.stemcellcenter.lu.se/article/stroke-researcher-receives-bengt-falcks-award - 2025-10-05

We are very happy to announce that Sandra Lindstedt - Professor of Cardiothoracic Surgery and Wallenberg Molecular Medicine clinical researcher - has joined Lund Stem Cell Center! Professor Sandra Lindstedt is a senior consultant in thoracic surgery specializing in heart and lung transplantation, with a long-standing interest in lung transplantation related research, post-transplant complications

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-welcomes-new-principal-investigator-sandra-lindstedt - 2025-10-05

CRISPR is a simple yet powerful Nobel Prize winning technology that allows sequence specific editing and manipulation of DNA sequences. The CRISPR facility at Lund Stem Cell Center is here to help you with your projects using this technology. What is CRISPR and who is it for? CRISPR started as a “traditional” gene editing tool, where a double stranded DNA break is introduced and repaired by the ce

https://www.stemcellcenter.lu.se/article/lund-crispr-facility-here-help - 2025-10-05

The results are in and it’s time to announce the winners of Lund Stem Cell Center Image Competition 2020. We are pleased to announce the winners of the Lund Stem Cell Center Image competition 2020 are:First place: Grasping at straws – Ludwig Schmiderer and Martin Hjort, Larsson group and NanolundSecond place: Floating – Maciej Ciesla, Bellodi groupThird place: Million dollars worth of antibodies –

https://www.stemcellcenter.lu.se/article/image-competition-2020-results - 2025-10-05

The leadership team set to guide Lund Stem Cell Center for the next three years was announced in early September 2020. In this interview with newly appointed coordinator Johan Jakobsson and deputy coordinator Johan Flygare, we hear about their future plans for this center of research excellence. What have been your first steps since taking over the reins at Lund Stem Cell Center? JJ: We have been

https://www.stemcellcenter.lu.se/article/plans-future-lund-stem-cell-center - 2025-10-05

Despite the ongoing pandemic, researchers from Lund Stem Cell Center are bringing science to schools both physically and using a digital platform. High school students across the Skåne region are learning about stem cell research in the ‘Taking science to schools – Borrow a scientist’ initiative, organized by the Research School in Stem Cell Biology.In this outreach project – planned for spring 20

https://www.stemcellcenter.lu.se/article/taking-stem-cells-high-schools-during-covid-19-pandemic - 2025-10-05