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The quality control of MHC class I antigen presentation

Popular Abstract in Swedish Ett antal olika behandlingsformer finns att tillgå vid angrepp av mikroorgansimer, tex antibiotika, samt vid uppkomsten av tumörer, tex strålbehandling och cellgifter. Ett alternativ till dessa traditionella behandlingssätt är att hjälpa kroppens immunförsvar att starta en specifik immunreaktion riktad mot de infekterade cellerna eller mot tumörcellerna. Detta vore en iMajor histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). Only properly assembled class I molecules loaded with high affinity peptides reach the cell surface. The mat

The safety of passengers in wheelchairs in special transportation services studied with interviews and assessments

It is important to provide scientific knowledge of wheelchairs as occupant-protecting seats in motor vehicles. This study aimed at examining the situation in Special Transportation Services (STS), an important mode of transport for wheelchair users in Sweden. The perceived safety levels were assessed and examined, and extensive field experience was gained. During the study in three Swedish cities

Cognitive approach to audio description

The article presents theoretical and methodological approaches relevant for the research on audio description (AD) and exemplifies the application of these approaches by studies on live audio description of films conducted at Lund University. A cognitive, reception-oriented perspective on AD and the framework of embodied cognition are in focus. It is claimed that previous research on scene percept