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Early changes in glomerular size selectivity in young adults with type 1 diabetes and retinopathy. Results from the Diabetes Incidence Study in Sweden.

Objective: To investigate the relationship between early-onset retinopathy and urinary markers of renal dysfunction. Research Design and Methods: The Diabetes Incidence Study in Sweden (DISS) aims to register all new cases of diabetes in young adults (15-34 years). In 1987-1988, 806 patients were reported and later invited to participate in a follow-up study focusing on microvascular complications

Changes in transport functions of isolated rabbit choroid plexus under the influence of oestrogen and progesterone

Isolated choroid plexuses from rabbits were used to determine uptake and accumulation of 10(-5) M radiolabelled choline (expressed as tissue/medium ratio) and the activities of various types of ATPases (based on ouabain inhibition and bicarbonate stimulation) following pre-treatment of the animals with 0.5 mg kg-1 17-beta-oestradiol, alone or in combination with 2 mg kg-1 progesterone. The combine

Fv structure of monoclonal antibody II-481 against herpes simplex virus Fc gamma-binding glycoprotein gE contains immunodominant complementarity determining region epitopes that react with human immunoglobulin M rheumatoid factors

Human immunoglobulin M (IgM) rheumatoid factors (RFs) show primary direct enzyme-linked immunosorbent assay (ELISA) reactivity with Fab rather than Fc fragments of monoclonal antibody (mAb) II-481 directed against the Fc gamma-binding site of herpes simplex virus glycoprotein gE. This preferential anti-Fab specificity suggests that RFs react with antigen-binding portions of mAb II-481 as anti-idio

Modelling of nonlinear effects and the response of ultrasound contrast micro bubbles: simulation and experiment

The propagation of diagnostic ultrasonic imaging pulses in tissue and their interaction with contrast micro bubbles is a very complex physical process, which we assumed to be separable into three stages: pulse propagation in tissue, the interaction of the pulse with the contrast bubble, and the propagation of the scattered echo. The model driven approach is used to gain better knowledge of the com

System Identification and LQG Control of Variable-Compression HCCI Engine Dynamics

The Homogenous Charge Compression Ignition (HCCI) combustion engine has potential to replace the spark ignition and compression ignition engines of today. One of the main problems in making the engine commercially attractive is the lack of direct means of controlling the ignition phasing. In this paper, we investigate the potential of inlet air temperature as a means to ignition actuation. This ar

Human renal epithelial cells express iNOS in response to cytokines but not bacteria.

BACKGROUND: Epithelial cells form the mucosal barriers that prevent the entry of mucosal pathogens, and respond to bacterial infections by producing various host defense molecules. In this study, we examined the inducible nitric oxide synthase (iNOS) response of primary human renal tubular epithelial cells (HRTEC) following infection with uropathogenic Escherichia coli Hu734, or stimulation with l

Auditory hemodynamic studies of newborn infants using near-infrared spectroscopic imaging

The noninvasive study of tissue blood volume and oxygenation using near-infrared light is a new and actively developing technology. We have used near-infrared spectroscopic imaging (NIRSI) to study hemodynamic responses on the auditory cortices evoked by auditory stimulation. Ten healthy newborn infants were studied. The otoacoustic emission hearing test was performed for each infant. Pulse oximet

Optimization of Au-assisted InAs nanowires grown by MOVPE

Epitaxially-grown InAs nanowires may have great potential for nanowire device applications, due to the high electron mobility and narrow direct band gap of this material. Various applications will most likely require different selected growth conditions, due to such factors as temperature-sensitive substrates or pressure-dependent intrinsic doping. However, it has been reported that InAs nanowires

Seeing the Word : John Dee and Renaissance Occultism

This study reassesses the occult philosophy of the British polymath John Dee (1527-1609). Focusing on his treatise Monas hieroglyphica (1564) and his notorious angelic conversations in the 1580s, it describes Dee’s philosophical career as a continuous search for a language which could yield knowledge of both nature and God. Situating Dee’s philosophy in the context of early modern “symbolic exeges

ELDERLY PERSONS LIVING WITH CANCER. Quality of life and lived experience.

Abstract in Danish Denne afhandling handler om livskvalitet hos ældre mennesker med kræft. Risikoen for at få kræft stiger med alderen, og til trods for at de fleste mennesker, der får kræft er ældre, har forskning i hvordan ældre lever med en kræftsygdom været yderst begrænset. Viden om hvordan ældre mennesker oplever det at få en kræftdiagnose og hvordan de lever med sygdommen er en forudsætningOver the coming decades, the numbers of elderly will increase, and through improved lifestyles and better treatment longevity has increased, and with it, the risk of contracting cancer. How elderly people live with cancer has until now attracted limited research. The overall aim of this thesis was to investigate the QoL of elderly persons from the time of a cancer diagnosis through the following s

Determining the Economic Effects of using Building Physics tools during the Building Process

Since the basic concepts in the area of building physics are usually ignored, preventable failures are continuing to occur in modern buildings. The aim of this project is to evaluate the economic effects of different building physics aspects during the different stages in the building process and show the importance of applying building physics to designs. The hypothesis of this project is that ec