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Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivation, with a large genetic deletion encompassing exon 4 to exon 21 of the Gpr116 gene. This model allowed us to confirm recent results defining Gpr116 a
Fuel ethanol production from lignocellulosic materials is at a level where commercial biofuel production is becoming a reality. The solubilization of the hemicellulose fraction in lignocellulosic-based feedstocks results in a large variety of sugar mixtures including xylose. However, allowing xylose fermentation in yeast that normally is used for fuel ethanol production requires genetic engineerin
We study the electrostatic confinement properties of a ballistic GaInAs nanostructure, a system with a high potential for quantum applications due to its small effective mass and persistence of quantum effects to higher temperatures. By measuring the magnetic depopulation of one-dimensional subbands in an etched quantum point contact, we demonstrate that the slope of the confinement at the Fermi l
We have developed a new approach for implementing precise intraprocedural control-flow and dataflow analyses at the abstract syntax tree level. Our approach is declarative, making use of reference attribute grammars augmented with circular attributes and collection attributes. This results in concise executable specifications of the analyses, allowing extensions both to the language and with furth
The aim of this paper is to specify a theory to explain why transitions to a market economy cause a shift to a higher level of innovation. Marketization increases the power of economic actors relative to political actors, increases inter-firm competition, creates new opportunities for entrepreneurship, and subsequently motivates innovative activity. For our empirical application, we focus on China
The mean size of fluorescent nanoparticles produced in a propane flame has been measured with an in-situ technique employing a femtosecond laser to excite the sample and a streak camera for time-resolved detection of the fluorescence. The time profile of the fluorescence anisotropy showed a Gaussian behaviour, typical of free rotor reorientation. By measuring its width, we estimated an average car
With increasing resistance development against conventional antibiotics, there is an urgent need to identify novel approaches for infection treatment. Antimicrobial peptides may offer opportunities in this context, hence there has been considerable interest in identification and optimization of such peptides during the last decade in particular, with the long-term aim of developing these to potent
We determine the spectrum of generalized Cesaro operators with essentially rational symbols acting on various spaces of analytic functions, including Hardy spaces, weighted Bergman and Dirichlet spaces. Then we show that in all cases these operators are subdecomposable. (C) 2009 Elsevier Inc. All rights reserved.
Osteoarthritis (OA) of the knee can be defined as primary (non-traumatic) or secondary (post-traumatic). Both non-traumatic OA and post-traumatic OA have been described predominantly in the medial compartment of the knee. The objective of this study was to compare the location of structural radiographic changes in non-traumatic OA and post-traumatic OA. A non-traumatic cohort, consisting of 155 pa
A cornerstone in the successful application of semiconductor nanowire devices is controlled impurity doping. In this review article, we discuss the key results in the field of semiconductor nanowire doping. Considerable development has recently taken place in this field, and half of the references in this review are less than 3 years old. We present a simple model for dopant incorporation during i
AimReal-life studies are needed to confirm the clinical relevance of findings from randomised controlled trials (RCTs). This study aimed to assess the effectiveness and tolerability of vildagliptin add-on vs. other oral antihyperglycaemic drugs (OADs) added to OAD monotherapy in a real-life setting, and to explore the advantages and limitations of large-scale pragmatic' trials. MethodsEDGE was a p
Hip fractures are devastating for the individual and a substantial economic burden for society. The treatment for displaced femoral neck fracture is a choice between internal fixation, total hip arthroplasty and hemiarthroplasty. As a result of several randomized trials, the treatment has shifted in Sweden from mostly internal fixation towards arthroplasties. There have been concerns about long-te
We study how the k dependence in the self-energy affects the quasiparticle band structure and one-particle spectral functions. It is known that, in electron-gas-like materials, the self-energy depends significantly on k and there is a strong cancellation between the k dependence and the energy dependence of the self-energy. Analysis of the GW self-energy reveals that, even in correlated materials
Recension av National Museum of the Pacific War, museum över Stillahavskriget i Fredericksburg, Texas.
Climate change mitigation and energy security are partly interacting areas that both present future challenges. The extensive research underway within these areas is mainly conducted in separate research communities, although there are some integrative efforts. This paper examines the breadth and heterogeneity involved in treating energy security and climate change mitigation as a combined researc
Det nya handboksförslaget granskas med avseende på språk och stil och med avseende på strukturen i gudstjänsten. Flera kritiska synpunkter på språk och stil ges, och placeringen av syndabekännelsen i gudstjänstens inledning liksom placeringen av förbönen mellan predikan och nattvard kritiseras, detta med utgångspunkt från hermeneutiska insikter, och från dramaturgisk analys.
Axonal outgrowth on smooth and porous silicon surfaces was studied in organ culture. The pore size of the silicon substrata varied between 100 and 1500 nm. We found that axons preferred to grow and elongate on porous silicon surfaces only when pores of (150-500 nm) are available.
Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.
