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Patient registries for home oxygen research and evaluation.

Randomized clinical trials are the preferred study design to address key research questions about the benefits or harms of interventions. However, randomized trials of oxygen therapy are difficult to conduct and have limitations. The purpose of this article is to offer our view on the potential use of patient registries in the field of home oxygen in COPD as an alternative to randomized trials by

https://www.lupop.lu.se/article/patient-registries-home-oxygen-research-and-evaluation-0 - 2025-11-30

Geographical proximity and the transmission of drug abuse among siblings: evaluating a contagion model in a Swedish National Sample.

The best-fit model predicted risk for DA in S2 as a function of the log of kilometres between S1 and S2 with parameter estimates (±95% confidence intervals) of 0.94 (0.92; 0.95). Prediction of DA included effects of cohabitation and an interaction of proximity and time since S1 registration with stronger effects of proximity early in the follow-up period. Proximity effects were stronger for smalle

https://www.lupop.lu.se/article/geographical-proximity-and-transmission-drug-abuse-among-siblings-evaluating-contagion-model-swedish - 2025-11-30

Geographical proximity and the transmission of drug abuse among siblings: evaluating a contagion model in a Swedish National Sample

The best-fit model predicted risk for DA in S2 as a function of the log of kilometres between S1 and S2 with parameter estimates (±95% confidence intervals) of 0.94 (0.92; 0.95). Prediction of DA included effects of cohabitation and an interaction of proximity and time since S1 registration with stronger effects of proximity early in the follow-up period. Proximity effects were stronger for smalle

https://www.lupop.lu.se/article/geographical-proximity-and-transmission-drug-abuse-among-siblings-evaluating-contagion-model-swedish-0 - 2025-11-30

EuroHeart: European Unified Registries On Heart Care Evaluation and Randomized Trials.

Major advances in cardiovascular medicine have been driven by innovations in basic research in biological and technical sciences. The subsequent testing in prospective randomized controlled trials (RCT) has provided the evidence underpinning the introduction of new, more effective, and safer treatments. New publication in European Heart Journal

https://www.lupop.lu.se/article/euroheart-european-unified-registries-heart-care-evaluation-and-randomized-trials - 2025-11-30

National poisoning registers and toxicovigilance in different countries as models for Germany

As of 2019, Germany has still not been able to provide a national poisoning register and toxicovigilance for sufficient and reliable information on human exposure for the purpose of identification and assessment of toxic risk to the public. In particular, the USA acts as a special model, but France, the Netherlands, Switzerland, and Sweden also have efficient poisoning registers and toxicovigilanc

https://www.lupop.lu.se/article/national-poisoning-registers-and-toxicovigilance-different-countries-models-germany - 2025-11-30

Prediction of Lymph Node Metastasis in Breast Cancer by Gene Expression and Clinicopathological Models: Development and Validation within a Population-Based Cohort

More than 70% of patients with breast cancer present with node-negative disease, yet all undergo surgical axillary staging. We aimed to define predictors of nodal metastasis using clinicopathological characteristics (CLINICAL), gene expression data (GEX), and mixed features (MIXED) and to identify patients at low risk of metastasis who might be spared sentinel lymph node biopsy (SLNB). New publica

https://www.lupop.lu.se/article/prediction-lymph-node-metastasis-breast-cancer-gene-expression-and-clinicopathological-models - 2025-11-30

Echocardiographic Findings in Patients with Mild to Moderate Chronic Kidney Disease without Symptomatic Heart Failure

A significant association between mild to moderate impairment of renal function and echocardiographic markers of cardiac structure and diastolic function was observed, supporting the hypothesis that interaction between the kidney and heart exists even in the early stages of renal impairment. Read the full paper here.

https://www.lupop.lu.se/article/echocardiographic-findings-patients-mild-moderate-chronic-kidney-disease-without-symptomatic-heart - 2025-11-30

Demographic and diagnostic profiles of older people with intellectual disability and prescription of antipsychotics

Older people with ID may be prescribed antipsychotic medication without thorough psychiatric diagnosing. Thus, there is a need for improving the abilities of health care professionals to properly diagnose and manage psychiatric illness in this population. Read the full paper here.

https://www.lupop.lu.se/article/demographic-and-diagnostic-profiles-older-people-intellectual-disability-and-prescription - 2025-11-30