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Quantifying the absorption and reduced scattering coefficients of tissuelike turbid media over a broad spectral range with noncontact Fourier-transform hyperspectral imaging
Absorption (mu (a)) and reduced scattering (mu (s)') spectra of turbid media were quanti fied with a noncontact imaging approach based on a Fourier-transform interferometric imaging system (FTIIS). The FTIIS was used to collect hyperspectral images of the steady-state diffuse reflectance from turbid media. Spatially resolved reflectance data from Monte Carlo simulations were fitted to the recorded
A systematic approach to robust preconditioning for gradient-based inverse scattering algorithms
This paper presents a systematic approach to robust preconditioning for gradient-based nonlinear inverse scattering algorithms. In particular, one- and two-dimensional inverse problems are considered where the permittivity and conductivity profiles are unknown and the input data consist of the scattered field over a certain bandwidth. A time-domain least-squares formulation is employed and the inv
The Pain Impact Inventory-Further Validation in Various Subgroups.
Objectives: The aim of the study was to further psychometrically evaluate the instrument "Pain Impact Inventory" (PII) in various subgroups. Methods: The sample comprised 384 persons (aged between 18 and 102 years) who reported chronic pain. The instrument PII was evaluated in terms of construct validity as well as reliability. The instrument's validity was investigated through corrected item-tota
No beneficial effects of levosimendan in acute porcine endotoxaemia.
Background: Levosimendan has been proposed as an attractive alternative to adrenergic agents for the treatment of sepsis-induced heart failure and haemodynamic derangements. Its use in this setting is, however, still not well investigated. The aim of this study was to test the hypothesis that levosimendan is able to attenuate endotoxin-induced pulmonary hypertension and improve myocardial function
First-Ever Atrial Fibrillation Documented After Hemorrhagic or Ischemic Stroke: The Role of the CHADS(2) Score at the Time of Stroke.
BACKGROUND: The CHADS(2) score (C, congestive heart failure [CHF]; H, hypertension [HT]; A, age ≥75 y; D, diabetes mellitus; S(2) , prior stroke or transient ischemic attack) is used to assess the risk of ischemic stroke in patients with atrial fibrillation (AF). However, its role in patients without documented AF is not well explored. HYPOTHESIS: The goal of the current study was to explore if th
Integrated Safety of Levodopa-Carbidopa Intestinal Gel From Prospective Clinical Trials.
Continuous administration of levodopa-carbidopa intestinal gel (carbidopa-levodopa enteral suspension) through a percutaneous endoscopic gastrojejunostomy is a treatment option for advanced Parkinson disease (PD) patients with motor fluctuations resistant to standard oral medications. Safety data from 4 prospective studies were integrated to assess the safety of this therapy.
Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates.
Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme
Toward Brain Tumor Gene Therapy Using Multipotent Mesenchymal Stromal Cell Vectors.
Gene therapy of solid cancers has been severely restricted by the limited distribution of vectors within tumors. However, cellular vectors have emerged as an effective migratory system for gene delivery to invasive cancers. Implanted and injected multipotent mesenchymal stromal cells (MSCs) have shown tropism for several types of primary tumors and metastases. This capacity of MSCs forms the basis
How many trials are needed to achieve performance stability of the Timed Up & Go test in patients with hip fracture?
OBJECTIVE: To examine the number of trials needed to achieve performance stability of the Timed Up & Go (TUG) test using a standardized walking aid in patients with hip fracture who are allowed full weight bearing (FWB). DESIGN: Prospective methodologic study. SETTING: An acute 14-bed orthopedic hip fracture unit. PARTICIPANTS: Patients (N=122; 89 women, 33 men) with hip fracture wit
The value of bladder mapping and prostatic urethra biopsies for detection of carcinoma in situ (CIS).
Study Type - Diagnostic (case series) Level of Evidence 4 What's known on the subject? and What does the study add? It is well known that CIS is a major risk factor for muscle-invasive bladder cancer and that this entity can be difficult to diagnose. Taking cold-cup mapping biopsies from different areas of the bladder (BMAP) is commonly used in patients at risk of harbouring CIS. The diagnostic ac
Chimney Grafts: Is There a Need and Will They Work?
Endovascular repair has become the primary treatment option for abdominal aortic aneurysms over the past decade. The favorable results as well as technical evolution have led endovascular repair to include fenestrated and branched technology for complex juxtarenal, suprarenal, and thoracoabdominal aneurysms. These grafts are, however, extensively customized and patient tailored at present precludi
Collocated electric and magnetic dipoles as a reference antenna for polarization diversity MIMO applications
In this letter, a magnetic dipole (M-dipole) and an electric dipole (E-dipole) are designed to form a collocated polarization-diversity-based dual-antenna system. The M-dipole is a modified shielded loop with multiple feed, and the E-dipole is a traditional λ/2 dipole. Measured results show that both radiators have ideal impedance matching and port isolation and identical omnidirectional pattern w
Mothers' sense of security in the first postnatal week: interview study.
persson e.k., fridlund b., kvist l.j. & dykes a.-k. (2010) Mothers' sense of security in the first postnatal week: interview study. Journal of Advanced Nursing. ABSTRACT: Aim. This paper is a report of a study of factors which influence mothers' sense of security during the first postnatal week. Background. Mothers' sense of security the first postnatal week is not thoroughly elucidated in the
The epidemiology of Graves' disease: Evidence of a genetic and an environmental contribution.
Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with r
Entering the White Space of Logistics Research,
Simulation of load carrying capacity of sheathed parallel timber beam structure
PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations.
Transfer RNAs (tRNAs) are essential for encoding the transcribed genetic information from DNA into proteins. Variations in the human tRNAs are involved in diverse clinical phenotypes. Interestingly, all pathogenic variations in tRNAs are located in mitochondrial tRNAs (mt-tRNAs). Therefore, it is crucial to identify pathogenic variations in mt-tRNAs for disease diagnosis and proper treatment. We c
The ELISA-Measured Increase in Cerebrospinal Fluid Tau that Discriminates Alzheimer's Disease from other Neurodegenerative Disorders is not Attributable to Differential Recognition of Tau Assembly Forms
Elevated cerebrospinal fluid concentrations of tau discriminate Alzheimer's disease from other neurodegenerative conditions. The reasons for this are unclear. While commercial assay kits are widely used to determine total-tau concentrations, little is known about their ability to detect different aggregation states of tau. We demonstrate that the leading commercial enzyme-linked immunosorbent assa