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Modern modular implants allow surgeons to mix different combinations of components within the same brand. From 1999 to 2012, the NexGen®-CR Option femoral component, together with a NexGen® Option Stemmed tibial plate (stemmed baseplate), which uses a short central stem, was the most-frequently used NexGen® combination in the Swedish Knee Arthroplasty Register. However, from 1999 to 2012, the same

https://www.lupop.lu.se/article/higher-risk-loosening-four-pegged-tka-tibial-baseplate-stemmed-one-register-based-study - 2025-10-03

Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. Read more at https://pubmed.ncbi.nlm.nih.g

https://www.lupop.lu.se/article/extrapancreatic-infections-are-common-acute-pancreatitis-and-they-are-related-organ-failure - 2025-10-03

To determine whether alcohol use disorder (AUD) is transmitted within families as predicted by contagion, we examined parent-offspring, siblings, and cousin pairs ascertained from Swedish registries with a primary case with AUD. Our outcome variable was AUD registration in at-risk secondary cases. In offspring, risks for AUD registration in the 3 years after a parental index registration residing

https://www.lupop.lu.se/article/within-family-transmission-alcohol-use-disorder-parent-offspring-sibling-and-cousin-pairs-contagion - 2025-10-03

Specific birth‐related fractures have been studied; underestimates might be a problem. We aimed to assess all fractures diagnosed as birth‐related as well as other neonatal fractures. Read more at https://onlinelibrary.wiley.com/doi/full/10.1111/apa.15217

https://www.lupop.lu.se/article/difficult-birth-main-contributor-birth-related-fracture-and-accidents-other-neonatal-fractures - 2025-10-03

Consecutively excised symptomatic foreskins from 351 men were sent for histopathological evaluation. During the surgical procedure, a fresh biopsy was taken for HPV analysis by modified general primer polymerase chain reaction. A medical questionnaire regarding medication, smoking habits, number of lifetime sexual partners, former diseases and surgery performed on penis was completed by all partic

https://www.lupop.lu.se/article/penile-intraepithelial-neoplasia-penile-cancer-precursors-and-human-papillomavirus-prevalence - 2025-10-03

To evaluate how surgeon heterogeneity – the variation in outcomes between individual surgeons – influences functional and oncological outcomes after robot‐assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP. Read more at https://bjui-journals.onlinelibrary.wiley.com/doi/full/1

https://www.lupop.lu.se/article/surgeon-heterogeneity-significantly-affects-functional-and-oncological-outcomes-after-radical - 2025-10-03

This was a cross‐sectional study based on data from 1591 adults (16–76y, median age 25y; 879 males, 712 females; Communication Function Classification System [CFCS] levels I–V) in the Swedish Cerebral Palsy Follow‐up Program. Pain severity was rated for several body sites and pain interference with activities/work and sleep was also evaluated. Logistic regression was used to estimate the odds rati

https://www.lupop.lu.se/article/prevalence-pain-and-interference-daily-activities-and-sleep-adults-cerebral-palsy - 2025-10-03

Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential associations between DM, C

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden-0 - 2025-10-03

Social and biological circumstances at birth are established predictors of adult socioeconomic position (SEP). This study aims to assess the trends in these associations across two generations and examine the effects of parental early-life characteristics on descendants’ adult SEP. Read more at https://jech.bmj.com/content/jech/early/2020/01/27/jech-2019-213209.ful…

https://www.lupop.lu.se/article/early-life-social-and-health-determinants-adult-socioeconomic-position-associations-and-trends - 2025-10-03

Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adverse birth ou

https://www.lupop.lu.se/article/occupational-exposure-whole-body-vibrations-and-pregnancy-complications-nationwide-cohort-study - 2025-10-03

Swedish national breast cancer guidelines recommend that all women diagnosed with breast cancer (BC) at the age of 35 years or younger should be referred to their regional oncogenetic clinic for genetic counseling and testing, regardless of family history of cancer. The main objective of this study was to evaluate whether place of residence at BC diagnosis and treating hospital were associated wit

https://www.lupop.lu.se/article/variations-referral-pattern-genetic-counseling-patients-early-onset-breast-cancer-population-based - 2025-10-03

The rise in antibiotic resistance is a global public health concern, and antibiotic overuse needs to be reduced. Earlier studies of out-of-hours care have indicated that antibiotic prescribing is less appropriate than that of in-hours care. However, no study has compared the out-of-hours treatment of infections to in-hours treatment within the same population. Read more at https://bmcinfectdis.bio

https://www.lupop.lu.se/article/diagnosis-linked-antibiotic-prescribing-swedish-primary-care-comparison-between-hours-and-out-hours - 2025-10-03

People who inject drugs (PWID) have increased risk of acquiring blood-transmitted chronic viral infections such as Hepatitis B (HBV), Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV) as well as increased risk of acquiring bacterial infections. We aimed to identify and describe bacteraemic episodes, their recurrence rates, predictive and prognostic factors amongst hospitalised PWID. Read mo

https://www.lupop.lu.se/article/prevalence-and-recurrence-bacteraemia-hospitalised-people-who-inject-drugs-single-centre - 2025-10-03

Previous research has shown that Common Mental Disorders (CMD) are unequally distributed between population subgroups, but we know less about how labour outcomes following such disorders are distributed. Our aim is to investigate how the labour outcomes following a CMD diagnosis differ over sex, age, schooling and country of birth. Read more at https://bmcpublichealth.biomedcentral.com/articles/10

https://www.lupop.lu.se/article/heterogeneity-associations-between-common-mental-disorders-and-labour-outcomes-population-study - 2025-10-03

Musculoskeletal pain is common in the general population and constitutes a major public health problem. A large proportion of these conditions may be work related. The aim of this study was to explore the relative importance of physical, psychosocial and personal factors, in number of pain sites and in five specific pain sites, among women in common professions with a broad variety of occupational

https://www.lupop.lu.se/article/impact-occupational-and-personal-factors-musculoskeletal-pain-cohort-study-female-nurses - 2025-10-03

In a recent population-based study, an elevated risk of the Metabolic syndrome (MetS) and type 2 diabetes was found in childless men compared to those who have fathered one or more children. Therefore, by using a larger cohort of more than 22 000 men from the Malmo Preventive Project (MPP) we aimed to expand our observations in order to evaluate the metabolic profile of childless men and to evalua

https://www.lupop.lu.se/article/male-childlessness-independent-predictor-risk-cardiovascular-and-all-cause-mortality-population - 2025-10-03

Hemopexin and α1-microglobulin act as scavengers to eliminate free heme-groups responsible for hemoglobin-induced oxidative stress. The present study evaluated maternal and fetal plasma concentrations of these scavengers in the different phenotypes of placenta-mediated disorders. Singleton pregnancies with normotensive fetal growth restriction [FGR] (n = 47), preeclampsia without FGR (n = 45) and

https://www.lupop.lu.se/article/hemopexin-and-a1-microglobulin-heme-scavengers-differential-involvement-preeclampsia-and-fetal - 2025-10-03

Welders are exposed to high levels of metal particles, consisting mainly of iron and manganese (Mn) oxide. Metal particles, especially those containing Mn can be neurotoxic. In this exploratory study, we evaluated associations between welding and expression of 87 putative neurology-related proteins in serum in a longitudinal approach. The study cohort from southern Sweden included welders working

https://www.lupop.lu.se/article/exposure-mild-steel-welding-and-changes-serum-proteins-putative-neurological-function-longitudinal - 2025-10-03

TheLIH is looking for new leadership to structure the Department of PopulationHealth focusing on multiple determinants of health and disease beyond ‘omics’,with an emphasis on social and environmental determinants that drive healthoutcomes and health inequities in the population and patient cohorts. Read more at https://www.lih.lu/jobs/detail/director-of-department-of-population-hea…

https://www.lupop.lu.se/article/director-department-population-health-un1020 - 2025-10-03

The extraordinary effort to speed the development of treatments and vaccines in response to the COVID-19 pandemic has put into sharp relief the need for the global science community to share scientific data openly. As the world’s largest funder of biomedical research, NIH is addressing this need with a new NIH Policy for Data Management and Sharing. This policy requires researchers to plan prospec

https://www.lupop.lu.se/article/statement-final-nih-policy-data-management-and-sharing - 2025-10-03