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PAX5 – a gene strongly associated with impaired insulin secretion in type 2 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 16 February 2023 Charlotte Ling, Tina Rönn, and Karl Bacos are three of the authors of a new study that has identified an important gene that affects insulin secretion. Photo: Petra Olsson Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-05-09

A genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects

By camilla [dot] selberg [at] med [dot] lu [dot] se (Camilla Selberg) - published 22 February 2023 First author Daniel E. Coral, LUDC researcher A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford univ

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-05-09

Swedish research about different forms of type 2 diabetes is relevant for Indian people

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 2 May 2023 Diabetes researcher Rashmi Prasad has led the research project about subgroups of type 2 diabetes in India. Photograph: Petra Olsson Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-05-09

Epigenetics and genetics help illustrate how diabetes care can be individualised

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 20 April 2023 Charlotte Ling’s research group has discovered epigenetic biomarkers that help them understand who will benefit from a common diabetes drug. Photo: Kennet Ruona Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? So

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-05-09

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 7 June 2023 Isabel Goncalves, Jiangming Sun, and Andreas Edsfeldt studying two atherosclerotic plaques. The study in JACC is based on a close collaboration between clinically active researchers and experts in bioinformatics. Photo: Petra Olsson A common cause of myocardial infarction and stroke is the rupture of atheroscle

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-05-09

Type 2 diabetes researchers receive support from the Hjelt Diabetes Foundation

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 5 September 2023 Jiangming Sun studies an atherosclerotic plaque. A goal with his research is to identify dangerous plaques at an early stage. The research project is now awarded a grant by the Hjelt Diabetes Foundation. Photograph: Petra Olsson Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-05-09

Gut and mouth bacteria give researchers new clues about atherosclerosis

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 13 July 2023 Bacterial species associated with early signs of atherosclerosis are linked to poor oral health in a new study. Daniel Jönsson, researcher and dentist, has examined the oral health of several of the participants. Photo: Petra Olsson What is the link between atherosclerosis and gut and mouth bacteria? Researche

https://www.ludc.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2025-05-09

Positive metabolic effects of gastric bypass disappear quickly

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 17 August 2023 In a new study published in the journal Obesity, the researchers studied the metabolism of overweight individuals before and after they had a gastric bypass operation. Photograph: iStock/herjua A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving ga

https://www.ludc.lu.se/article/positive-metabolic-effects-gastric-bypass-disappear-quickly - 2025-05-09

New study: Virus of importance in the development of type 1 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 8 September 2023 Swedish children have contributed to a new study that supports the theory that certain viruses are important for the development of type 1 diabetes. Photo: Johan Persson New research supports the theory that certain viral infections are of importance in the development of type 1 diabetes. An international

https://www.ludc.lu.se/article/new-study-virus-importance-development-type-1-diabetes - 2025-05-09

The Scientific Advisory Board: “Important contributions within type 1 diabetes research”

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 11 October 2023 Frances Ashcroft and Flemming Pociot from LUDC’s Scientific Advisory Board spent their time at the retreat listening to presentations and getting updates. Photo: Petra Olsson Lund University Diabetes Centre’s Scientific Advisory Board give researchers valuable feedback on ongoing research. Frances Ashcroft

https://www.ludc.lu.se/article/scientific-advisory-board-important-contributions-within-type-1-diabetes-research - 2025-05-09

New report highlights opportunities and challenges for precision diabetes medicine

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 5 October 2023 Using precision medicine in diabetes means that treatment of the disease and its complications can become more precise and accurate. Photo: iStock/Maya23K An international consensus report on diabetes identifies the potential for diabetes screening, better classification of type 2 diabetes, and biomarkers th

https://www.ludc.lu.se/article/new-report-highlights-opportunities-and-challenges-precision-diabetes-medicine - 2025-05-09

Research on inherited type 2 diabetes is awarded

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 6 November 2023 Rashmi Prasad is awarded the Medeon stipend 2023 for her her research on heritability of type 2 diabetes. The stipend will be presented during the World Diabetes Day Skåne event. Photo: Petra Olsson How do heritability and the fetal environment affect the risk for the child to develop type 2 diabetes? This

https://www.ludc.lu.se/article/research-inherited-type-2-diabetes-awarded - 2025-05-09

Innovation that aims to identify dangerous atherosclerotic plaques wins prize

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 15 November 2023 Magnus Cinthio, Isabel Goncalves and Tobias Erlöv win Lund University’s and Sparbanken Skåne’s award for Future Innovations to develop their idea further. Photo: Kennet Ruona Diabetes researcher and cardiologist Isabel Goncalves at Lund University Diabetes Centre (LUDC) has teamed up with ultrasound resear

https://www.ludc.lu.se/article/innovation-aims-identify-dangerous-atherosclerotic-plaques-wins-prize - 2025-05-09

Epigenetic changes can cause type 2 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 12 December 2023 Tina Rönn, Charlotte Ling, and Karl Bacos have led the work on a study that examines whether epigenetic changes contribute to the development of type 2 diabetes. Photo: Petra Olsson Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by resea

https://www.ludc.lu.se/article/epigenetic-changes-can-cause-type-2-diabetes - 2025-05-09

New study: Biomarkers that improve prediction of cardiovascular disease in type 2 diabetes

By press [at] med [dot] lu [dot] se (Faculty of Medicine at Lund University) - published 26 January 2024 Out of the 195 biomarkers examined, 13 were significantly associated with cardiovascular risk in people with type 2 diabetes. Photograph: iStock An international team of researchers has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease

https://www.ludc.lu.se/article/new-study-biomarkers-improve-prediction-cardiovascular-disease-type-2-diabetes - 2025-05-09

The protein that protects insulin-producing cells

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 15 February 2024 Anna Blom and Ben C King have discovered that C3 protein protects insulin-producing cells. Photo: Rebecca Rosberg Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. Researchers at Lund University have instead chosen to investigate what protects t

https://www.ludc.lu.se/article/protein-protects-insulin-producing-cells - 2025-05-09

New coordinators for strategic research area in diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 28 February 2024 Coordinator Allan Vaag and Vice Coordinator Lena Eliasson lead the activities at EXODIAB and LUDC in close collaboration. Photograph: Petra Olsson Diabetes researchers Allan Vaag and Lena Eliasson are the new coordinators of Lund University Diabetes Centre (LUDC) and the strategic research area EXODIAB (Ex

https://www.ludc.lu.se/article/new-coordinators-strategic-research-area-diabetes - 2025-05-09

Tune H Pers receives award for outstanding research on obesity and diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 20 February 2024 Tune H Pers is the recipient of the Leif C. Groop Award for Outstanding Diabetes Research in 2024. Photograph: Peter Andrew Stanners Do you think that people with obesity have themselves to blame? Tune H Pers tries to dispel persistent myths through his research on the brain's role in the development of ob

https://www.ludc.lu.se/article/tune-h-pers-receives-award-outstanding-research-obesity-and-diabetes - 2025-05-09

New treatment of atherosclerosis may reduce the risk of dying from a heart attack

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 18 April 2024 Vikas Yadav, Jan Nilsson, and Filiz Serifler at Lund University Diabetes Centre have contributed to the studies of the antibody that neutralises oxidised LDL particles. Photograph: Petra Olsson A treatment that has reduced plaque development in mice has now been tested in people with psoriasis. Jan Nilsson at

https://www.ludc.lu.se/article/new-treatment-atherosclerosis-may-reduce-risk-dying-heart-attack - 2025-05-09

Research on obesity and gestational diabetes receive support from Hjelt Diabetes Foundation

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 21 May 2024 Sebastian Kalamajski edits fat cells with the editing technique CRISPR-Cas9. The aim with his project is to identify genetic variants and molecular pathways behind obesity that does not lead to type 2 diabetes. Photograph: Petra Olsson Why are some people with obesity protected from type 2 diabetes? Who is at r

https://www.ludc.lu.se/article/research-obesity-and-gestational-diabetes-receive-support-hjelt-diabetes-foundation - 2025-05-09