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Metastatic breast cancer (MBC) is generally considered an incurable disease and even though new treatments are available, the median survival is approximately three years. The introduction of immune therapies for MBC highlights the importance of the immune system in cancer progression and treatment. CD163+ anti-inflammatory myeloid cells, including tumor associated macrophages (TAMs), are known to
Although it is widely recognized that leadership concerns organizing future actions and mobilizing organizational actors to pursue them, our understanding of how this is accomplished in situated work interactions is relatively limited. Recent ethnographic studies have focused on leadership work resulting in the emergence of direction. This study explores the efforts involved in attempting to mobilAlthough it is widely recognized that leadership concerns organizing future actions and mobilizing organizational actors to pursue them, our understanding of how this is accomplished in situated work interactions is relatively limited. Recent ethnographic studies have focused on leadership work resulting in the emergence of direction. This study explores the efforts involved in attempting to mobil
"Knivkontakt" av Hagelsteen & Frost - din guide till en framgångsrik ST i kirurgiska specialiteter. Lär dig navigera i kirurgvärlden, ta ansvar för ditt lärande, hantera utmaningar och utveckla rätt mindset. Praktiska tips från erfarna kirurger i fickformat!Finns nu hos alla nätbokhandlare. Kliniker som önskar köpa större volymer till rabatterat pris kan kontakta författarna.
Att arter har begränsade geografiska utbredningsområden beror ofta på en begränsad förmåga att anpassa sig till de miljöförhållanden som råder utanför arternas utbredningsgränser. På grund av pågående klimatförändringar kan dock de miljöförhållanden som råder inom arters nuvarande utbredningsområden komma att ändras inom den närmaste framtiden. För att undgå utrotning kommer därför många populatioThe fact that species have limited ranges is often due to a limited ability to adapt to the environmental conditions that occur outside their geographic ranges. However, due to ongoing climate change, the environmental conditions within species’ geographic ranges may change in the near-future. To avoid extinction, many populations therefore need to migrate to new areas and/or adapt to the new cond
BACKGROUND: The efficacy of corticosteroids for treating acute vestibular neuritis, or acute unilateral vestibulopathy (AUVP), remains controversial.OBJECTIVE: This study aimed to evaluate whether corticosteroids improve vestibular function and reduce symptoms in both acute and chronic phases of AUVP.METHODS: This randomized, placebo-controlled, double-blind trial included patients with AUVP (ages
We report on neutron scattering measurements on the vortex lattice of the noncentrosymmetric superconductor BiPd. We observe the existence of the intermediate mixed state, a region where Meissner and vortex lattice phases coexist, which is a feature of low 𝜅 type-II superconductors. Following this, we obtain an estimate of the value of 𝜅 using the extended London model. Finally, we find that the
BACKGROUND: Perfluoroalkyl substances (PFAS) are stable chemicals used in various applications. PFAS exposure has been associated with lower birth weight and immunological effects in children, and limited evidence further suggests adverse neurodevelopmental effects. Previous studies show that PFAS cross the placental barrier during pregnancy leading to prenatal exposure of the fetus. Research on t
ABSTRACTObjectivesAn emerging body of research reveals a heightened risk of gambling problems among elite athletes, particularly among males, but these studies often suffer from small sample sizes and lack diverse representation across sports and groups. This study aimed to investigate gambling problems and their correlates among elite male and female ice hockey players in Sweden’s top leagues.Met
The demand for cost- and time-effective and customizable components for High Vacuum (HV) and Ultra-High Vacuum (UHV) systems has prompted exploration into the application of 3D-printing technology. This study investigates the viability of utilizing 3D-printed plastics in UHV environments by evaluating their outgassing properties. An extensive evaluation of 3D-printing materials was carried out, hi
Toxicity pathways of engineered carbon nanomaterials, which have many and diverse industrial applications, include oxidative stress primarily due to the generation of reactive oxygen species (ROS). This study on 13 carbon black, 6 Graphene nanoplatelets (GNP), and 3 nanodiamond materials identified physicochemical properties driving their ROS production. ROS production was cross-validated using di
This paper examines the influence of artificial intelligence (AI) on recent operatic practice, exploring its potential to affect the development of the genre from the artist’s perspective. While opera has historically evolved in tandem with technological advancements, the integration of AI raises important questions about its function within the operatic toolbox and its relation to the genre’s cor
Let f be a holomorphic self-map of the unit disc. We show that if log(1 − | f (z)|) is integrable on a sub-arc of the unit circle, I , then the set of points where the function f has finite Carathéodory angular derivative on I is a countable union of Beurling–Carleson sets of finite entropy. Conversely, given a countable union of Beurling–Carleson sets, E , we construct a holomorphic self-map of t
ESP18-0638
It was not a given that petrol-powered cars would come to dominate the world. In fact, back in 1900, just 22% of cars produced in the US were powered by gasoline (also known as petrol, benzine or various other names). The rest split between electric and steam cars.
Detta är nederländsk bearbetning och översättning av min svenska biografi om Kleopatra.
The use of carbonic anhydrase (CA) as a catalyst for bicarbonate formation in amine solutions has shown the potential to increase the absorption rate of CO2, thus potentially reducing capital cost of a CO2 capture plant, as the size of equipment can be reduced. On another approach, it could replace part of the amine to offer lower environmental impact. In this work, the catalytic effect of CA on t
Background: Interferon-γ release assays (IGRAs) for tuberculosis infection (TBI) cannot distinguish different stages of the TBI spectrum (including spontaneously cleared infection). We investigated patterns of Mtb-specific blood mediators in people with and without TBI during tuberculosis preventive therapy (TPT). Methods: Individuals with likelihood of recent Mtb exposure, aged 15–25 years, with
