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Introduction: Dementia remains incurable, and treatment trials are typically conducted after the symptoms manifest, potentially too late in the disease process to alter its course. Early identification and intervention during the pre-diagnosis phase offer the potential to introduce more cost-effective strategies and enhance quality of life. This review aims to scrutinise emerging evidence and pres
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In recent years, the prevalence of idiopathic pulmonary fibrosis (IPF) and post-COVID-19 pulmonary fibrosis has risen. Nevertheless, effective diagnostic and prognostic biomarkers alongside targeted treatments are lacking, making lung transplantation the last resort for many patients with end-stage disease. However, bronchiolitis obliterans syndrome (BOS), a manifestation of chronic lung allograft
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This study explores how social origin, reflected by occupation and family name from both parents, has been passed down over the past 150 years in Sweden. It finds that intergenerational rank-rank associations in occupational status – a typical measure of social mobility – have remained surprisingly constant at levels around 0.27 – as in the US (Song et al., 2020). However, intergenerational correl
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Static code checkers are tools that help software engineers by automatically finding defects without executing the programs. These tools contain a set of detectors that rely on static program analyses to find common programming defects or to enforce coding guidelines.While existing code checker frameworks package a rich collection of detectors, aimed at common bug defects, the effort to adapt thes
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Type 1 diabetes is a chronic, autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Early detection can facilitate timely intervention, potentially delaying or preventing disease onset. Circulating proteins reflect dysregulated biological processes and offer insights into early disease mechanisms. Here, we construct a genome-wide pQTL map of 1985 protein
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Kultfilmsevenemang som Den Dåliga Filmfestivalen (Göteborg, 2019 och 2023-2025) och B-Filmsklubben (Malmö) erbjuder unika atmosfärer för publiken som besöker dem. I Malmö och Göteborg anordnar biograferna regelbundet festivaler och fristående visningar av kultfilmer som band andra The Room, Birdemic, och Miami Connection. Kännetecknande för dessa upplevelser är den översvallande atmosfär som skapaCult film events like The Bad Film Festival (Gothenburg, 2019 and 2023-2025) and The B-Film Club (Malmö) offer unique atmospheres to audiences. In the two Swedish cities of Malmö and Gothenburg, exhibitors run regular festivals and standalone screenings of cult films such as The Room, Birdemic, Miami Connection, and others where an effervescent atmosphere is generated, often featuring audience par
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PURPOSE: Posterior fossa tumour (PFT) surgery carries a risk of mutism or severely reduced speech. As for higher-cognitive language functions, word-finding difficulties have been reported, but no study has compared pre- and postoperative word-finding speeds to identify impairment caused by surgery. The current study investigated changes in word-finding ability associated with PFT surgery and exami
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The increasing demand for energy-efficient and sustainable construction necessitates the need for building envelope designs that effectively balance moisture safety with sustainability. Improper moisture management in building envelopes can lead to severe consequences, including construction damage, decreased energy performance, and health risks associated with microbial growth. For instance, wate
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Autofluorescence poses an impediment to fluorescence microscopy of biological samples. In the Gram-positive, soil-dwelling bacteria of the genus Streptomyces, sources of autofluorescence have not been examined systematically to date. Here, we show that the model organism for the genus, Streptomyces venezuelae, shows autofluorescence in two of the commonly used fluorescence channels for visualizing
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BACKGROUND: The cerebellar mutism syndrome (CMS) is one of the most disabling late effects after neurosurgery for a posterior fossa tumour in childhood. The reported incidences vary substantially in previous studies. AIMS: Pathophysiology is unknown, but damage to cerebello-thalamo-cerebral circuits is likely. The study focuses on the risk factors for development and severity of CMS including surg
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The evolution of the fifth-generation network (5G) increases the demand and use of Internet of Things (IoT) devices extensively. The increased number of IoT devices increases the possibility of new attack surfaces, and thus even resource-constrained IoT devices need secure communication. In this work, we consider the Julia Key Agreement (JKA) protocol, which has been proposed as a secure and effic
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The role of the vitamin D receptor (VDR) in inflammatory bowel disease (IBD) is poorly described. The aim of this study was to examine the relationship between immunohistochemical VDR expression and IBD activity. The immunohistochemical expression of VDR was analysed in biopsies from active and inactive IBD in 28 patients (ulcerative colitis: 21, Crohn's disease: 7) and 12 non-IBD controls. VDR ex
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Software is at the core of digitalisation and is often claimed to play a central role in innovation and in shaping competition across industries and firms. There are yet few studies of the extent and nature of software development across firms. We employ a unique firm-level survey comprising 3,929 firms across Sweden to analyse the distribution and characteristics of firms that invest in software
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For the past decade, the sharing economy has not only grown but also expanded to cover a wide variety of different activities across the globe. Despite a lot of research, there is still no agreement on how to define and measure the sharing economy, and no consensus on whether the sharing economy is a part of or an alternative to a regular capitalist economy. This paper contributes by presenting a
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Background: Certain species from the normal respiratory tract microbiota have recently been proposed to positively influence human health. Corynebacterium propinquum and C. pseudodiphtheriticum (Corynebacteria) are two Gram-positive species that frequently colonize the upper respiratory tract and strongly associate with a reduced incidence of respiratory tract infections. The specific role of Cory
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While digitalisation is oftentimes thought of as a global megatrend and something that transcends national borders and geographical distances, it is at the same time a very tangible process exhibiting considerable regional and sectoral variation. Against this backdrop, Digital Innovation Hubs (DIHs) (a policy initiative in the context of the Digitising European Industry (DEI) strategy of the EU) c
