Lysosomes are cell organelles in charge of degradation. Lysosomal membrane permeabilization (LMP) causes the leakage of cathepsins and other digestive enzymes into the cytosol from lysosomal cavities. This usually causes the initiation of cell death. LMP can be triggered by many stimuli and this could potentially be used in new therapeutic approaches for removing cancer cells. However, excessive L

The subject of diophantine approximation is a classical mathematic problem, as old as it is well studied. There are many different texts describing its connection to more modern areas of study, but few which do so with the aim of exploring the connections themselves. This paper aims to serve as an introduction to diophantine approximation, and to expose some properties common between two dynamical

The essay aims to examine alternative forms of housing, especially collective solutions and to design a cohousing project. The idea is to broaden our perception of housing and further study the possibilities of cohousing in relation to the more complex needs and different lifestyle of today. The housing market of today is still based upon the idea of an autonomous nuclear family with a lot of priv

This paper explores the process of transitioning to a rural, self-sustainable lifestyle in terms of ecological sustainability and geographical place, while focusing on how these concepts serve to motivate change and create a sense of purpose. It further analyzes how aspects of structural power may facilitate or impede the transition into self-sufficiency. The study consists of ethnographically ga

Syfte: Syftet med uppsatsen är att utveckla förståelsen för den påverkan som skiftande styrning har på anställda inom en organisation. Metod: Abduktivt tillvägagångssätt. Totalt 13 semistrukturerade kvalitativa intervjuer på ett fallföretag. Teoretiska perspektiv: Det huvudsakliga perspektivet för analysen är social identitetsteori. En litteraturgenomgång av traditionell och nutida forskning angPurpose: The purpose of the thesis is to develop an understanding of the impact that varied organizational control has on employees within an organization. Methodology: Abductive approach. A total of 13 semi-structured qualitative interviews at a case company. Theoretical perspectives: The main perspective is through the social identity theory. A literature review of traditional and contemporary

Bakgrund: De individer som drabbas av ett venöst bensår kommer troligen att leva med det under en lång tid. Det är även ett välkänt problem att dessa individer upplever svårigheter i sin vardag samt det är ett komplext problem som inte endast kan lösas genom såromläggningar. Syfte: Att beskriva personers upplevelser av att leva med ett venöst bensår. Metod: 12 kvalitativa studier valdes ut och en

The recent addition of Modern Standard Chinese (MSC) as an elective language in Swedish elementary and high school ('Moderna Språk') has brought the teaching of MSC particle le to the fore. Le occurs either affixed to a verb (le1) or as a sentence-final particle (le2) and is a frequently used grammatical device in MSC with a great number of various functions. At the same time, coexistent a

This thesis is concerned with history within Nick Clegg’s and Nigel Farage’s political discourse during the six months leading up to the 2016 referendum on the United Kingdom’s membership in the European Union. Using Thematic Analysis combined with Klas-Göran Karlsson’s typology of the use of history, Jörn Rüsen’s typology of historical narrative and drawing on the theoretical framework of histori

Bolivia has experienced a drastic decline in inequality and poverty since 2000. It coincided with the administrative period of Evo Morales between 2006 and 2019. Hence, it is debated whether poverty reduction was mainly driven by economic growth alongside the commodity boom in the 2000s or by policy implementations during Morales’s presidency. This study addresses the research question: “How and w

In recent years many devices such as smartphones, smart watches and laptops have started being equipped with embedded SIM cards called eSIM, which have the possibility to be reprogrammed with new subscription data through a process called remote SIM provisioning. To enable the eSIM in these devices, the mobile operators have had to implement new systems for the remote SIM provisioning process, and

Forskning inom interstellära objekt, det vill säga objekt som har sitt ursprung utanför vårt solsystem, har pågått under decennier, men det var inte förrän 2017 som det första interstellära objektet i solsystemet upptäcktes. Det fick namnet 1I/'Oumuamua och skapade ett stort intresse både inom forskarvärlden och hos allmänheten. Två år senare, 2019, upptäcktes det andra och senaste interstelläResearch on InterStellar Objects (ISOs) has been done for several decades, however, the first observed ISO in the Solar system was only recently discovered in 2017. It was named 1I/'Oumuamua and was only passing though the Solar system, but this may not be the case for all objects of its kind. For instance, one could gain a bound orbit around the Sun if the right amount of nudge is acquired wh

The results confirm the general claim that extreme skewness is a result of long-term com-pounding induced by a single period standard deviation. The results confirm that the Swedish stock market has the same characteristics as that of the US market. I estimate that the Swe-dish stock market produced 1.2tnSEK wealth 1984 – 2018 – with an extreme concentration of 28 stocks representing all wealth cr

Äldre anställdas ställning på arbetsmarknaden är onekligen osäker. I detta arbete försöker jag att räta ut och förstå hur äldre arbetstagare är skyddade på arbetsmarknaden genom att undersöka hur gällande rätt är designat. Detta görs genom en komparativ studie mellan Sverige och Kina, där en rad olika undersökningsområden kopplat till anställningsskydd för äldre bearbetas. Arbetet berör och förklaThe status of the elderly on the labour market is undeniably precarious. In this thesis, I am trying to straighten out how the elderly are protected on the labour market and how the legislation to protect them is designed. This is done through a comparative study between Sweden and China, where a number of research areas associated with employment protection for elderly are processed. I am, in thi

Syftet med den här studien var att undersöka hur kommunikatörer upplevde att digitaliseringen har påverkat deras kompetens och sätt att arbeta med intern kommunikation inom offentlig sektor. Studiens avsikt var att bidra med kunskap om kommunikatörers mångtydiga roll och vilken betydelse interna kommunikationsdokument hade för deras praktiska arbete. För att samla in empiriskt material har en kvalThe purpose of this case study was to investigate how communicators perceived that digitalization had affected their competence and work with internal communication in the public sector. The intention of the study was to contribute with knowledge regarding communicators ambiguous role and the importance of internal communication documents for their practical work. This study was conducted through

Denna studie undersöker personalisering av politik och syftar till att åskådliggöra hur personliga och politiska berättelser konstrueras och förhåller sig till varandra på en samtida politikers egen kommunikationskanal. Tidigare forskning har tenderat att bortse från dessa kanaler och har främst fokuserat på personalisering av politik utifrån ett nyhetsmediaperspektiv. Det råder en brist på konsenThis study examines the personalization of politics and aims to investigate how personal and political narratives are constructed and related to each other on a politician's own communication channel. Previous research has tended to disregard these channels and mainly focused on personalization from a news media perspective. Whilst there is a lack of consensus regarding the spread of personali

I denna studie undersöks bildningsprocesser och klimatologisk betydelse av hur av årsmoräner bildas vid Gornergletscher, en stor alpin dalglaciär i de södra schweiziska Alperna. Ett särskilt fokus ligger på moränryggar som har bildats mellan 2007 och 2019, en period då glaciären har retirerat snabbt och det har skett en tydlig förtunning av isfronten. Dessa moräner uppvisar olika geomorfologiska oThis study examines genetic processes and climatological significance of annual moraine formation in the foreland of Gornergletscher, a large alpine-valley glacier located in the southern Swiss Alps. A particular focus is set on moraine ridges that have been forming between 2007 and 2019, a period when the glacier has been subject to accelerated retreat and pronounced frontal thinning. These morai

I denna uppsats har vi med hjälp av retoriska verktyg som stilfigurer, Toulmins argumentationsmodell samt argumentativa grundbegrepp genomfört en deskriptiv redogörelse för vilka retoriska element som Statsminister Stefan Löfvens “Tal till nationen” innehåller. Dessa har vi disponerat efter dispositio och därefter analyserat utifrån en prisma av teorier om nationen och nationsidentitet. Analysen rIn this thesis, through the use of rhetorical tools, we have carried out a descriptive report of the rhetorical elements found in Prime Minister Stefan Löfven’s speech “Speech to the nation”. These we have arranged by disposition and analyzed through a prism of theories of nation and nation identity. This analysis resulted in an insight that through the speech, the Swedish nation actually presents

Due to globalization, increasing amounts of water are traded across borders as virtual water embodied in traded products. The thesis traces global water trade patterns at different levels of income between 1990 and 2015 in order to test whether developed countries outsource their water-intensive production to less developed countries increasing global water use in the process. The research problem

This thesis explores the radioactive image and poses the multi-layered question: ‘(how) can radioactivity exist as an image, when it cannot be seen, heard or felt?’. By having no sensorial qualities, radioactivity is often narrated in popular media by metaphoric association. Through close analyses of selected scenes from HBO’s tv-series Chernobyl (2019) the study suggests that a variety of tropes

Visste ni att världens jordar innehåller mer än dubbelt så mycket kol som atmosfären och mer än tre gånger så mycket som alla växter? Mikroorganismer i jorden, som bakterier och svampar, står för en betydande del av koldioxidflödet mellan jorden och atmosfären. Idag ser vi klimatförändringar som innebär längre perioder med torka och intensivare regn. Mikroorganismer i marken likt alla andra påveClimate change will result in altered precipitation cycles, which might reduce the soil carbon storage. Respiration and growth by soil microbes including fungi and bacteria, play an important role in regulating the terrestrial carbon cycle and thus have an impact on climate feedbacks. It has been shown that microbes can respond in two different patterns after drought followed by rewetting, either