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Strengthening international climate governance is seen as pivotal for advancing the Sustainable Development Goals (SDGs). However, a systematic understanding of their dynamic interactions remains limited. Given the strong interconnections among the SDGs, climate governance policies designed to advance one goal can significantly influence progress on others, highlighting the need for an integrated
This thesis consists of three self-contained papers that examine how information and ideologies serve as coordinating forces during episodes of political and social transformation.The first paper studies how shifts in public sentiment can trigger mass mobilization, using the Finnish Civil War of 1918 as a natural experiment. I show that the abrupt abolition of Russian imperial censorship in 1917 p
Circular supply chains (CSCs) depend on enhanced supply chain visibility (SCV) to track and manage resource flows and thereby enable efficient decision-making. Despite confronting silo mentalities, fragmented information, technological barriers, resistance to change, and a lack of standardization, data sharing remains crucial for SCV and circularity. In this study, following the Delphi method, 22
De 6-åriga läkarprogrammen ger legitimation och förskrivningsrätt direkt efter examen.En nationell arbetsgrupp har tagit fram förslag till hur läkarstudenter under grundutbildningen ska ges möjligheter att träna på läkemedelsbehandling samt hur lärosätena ska kunna examinera kunskaper och färdigheter.Gruppen föreslår ökad tydlighet i kedjan lärandemål–aktiviteter–examination, färdighetsträning i d
This paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD. Our findings confirm that the integration of climate chanThis paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD. Our findings confirm that the integration of climate chan
SammanfattningKapitel 5 behandlar en ny cancerbehandlings strategi som kombinerar: Joniserande strålning med Elektrisk pulsterapi (elektroporation).Målet är att förbättra naturförstörelsen, samtidigt som immunförsvaret stimuleras.Initiala Prekliniska fynd (djurstudier)Experiment på råttor med gliomtumör testade effekten av enbart strålning(RAD), enbart elektriska pulser(PEF) och en kombination av
Sammanfattning av ver. 2 Nästa generation av tumörbehandling? Pre-kirurgisk intermittent strålbehandling kombinerad med immunterapi (PSiRIT).Grundtanken är att använda strålningens läkande krafter genom att med en låg dos strålning på 6 till 8 Gy före operation, kombinerad med immunstimulerande behandling aktivera kroppens immunförsvar mot tumören, förbättra behandlingsresultat och potentiellt upp
Epigenome-wide studies of pancreatic islets provide valuable insights into type 2 diabetes (T2D) but lack methylomes from individual cell types. Here we show changes to alpha and beta cell-specific methylomes and transcriptomes from people with or without T2D, using whole-genome bisulfite sequencing and RNA sequencing. We discover 22,544 differentially methylated regions annotated to 7,975 genes i
ABSTRACT Background Posterior fossa tumours (PFT), among the most common childhood brain tumours, place children at risk of speech, language, and communication difficulties, often described in relation to cerebellar mutism syndrome (CMS) but also seen in children without mutism. Narrative ability refers to the capacity to understand, create, and share stories. Narratives can be analysed at the macBackgroundPosterior fossa tumours (PFT), among the most common childhood brain tumours, place children at risk of speech, language, and communication difficulties, often described in relation to cerebellar mutism syndrome (CMS) but also seen in children without mutism. Narrative ability refers to the capacity to understand, create, and share stories. Narratives can be analysed at the macrostructur
Malaria caused by Plasmodium falciparum (P. falciparum) remains a major cause of morbidity and mortality, particularly in sub-Saharan Africa. Immunity develops gradually after repeated exposure and is largely mediated by antibodies, yet the mechanisms regulating the development and function of humoral immunity, including the roles of B-cell subsets and inflammatory mediators, remain incompletely u
This dissertation investigates how the ageing process affected income, work, and family structures, and how broader economic forces shaped the living standards of older adults in 19th-century Stockholm. It situates individual life cycles within the wider context of 19th-century economic and demographic change. Through an integrated micro-historical analysis of household earnings, savings, poverty
The expansion of e-commerce and the consequent spatial changes raise questions about how accessibility and liveability for older people is considered in increasingly ageing societies. The aim of this article is to enhance the understanding of how digitally literate older people perceive e-commerce as a tool to accommodate their needs. The study therefore poses the question: How do digitally litera
BackgroundWireless pH-monitoring is an accurate method for diagnosing adults with gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the use of the Bravo capsule on children investigated for GERD in terms of safety, tolerability and feasibility before and after administration of proton pump inhibitors.MethodsA Bravo capsule was inserted during upper endoscopy under gener
There is growing interest in using digital technology like welfare technology (WT) to support older adults (aged 75+) to age in place, particularly in Nordic countries. This cross-sectional survey study (n = 414), conducted in 18 Swedish municipalities, used descriptive statistics and binary logistic regression to examine: user experiences related to satisfaction with WT, as well as users’ expectaThere is growing interest in using digital technology like welfare technology (WT) to support older adults (aged 75+) to age in place, particularly in Nordic countries. This cross-sectional survey study (n = 414), conducted in 18 Swedish municipalities, used descriptive statistics and binary logistic regression to examine: user experiences related to satisfaction with WT, as well as users’ expecta
ObjectivesAutoantibodies against tissue transglutaminase (tTG) are serological markers of celiac disease. The aim was to study the applicability of human leukocyte antigen (HLA)-genotyping and tTG autoantibodies in the screening of celiac disease in a longitudinal birth cohort followed to age 15 years.MethodsIncluded were 13,860 HLA-DQ-genotyped children at birth and previously invited to a screen
ObjectivesOur aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD).MethodsThe Celiac Prediction in Skåne study prospectively followed 5969 human leukocyte antigen (HLA)-genotyped children born 2001–2004 who were screened for CeD at ages 3, 9, and 15 years in Skåne, Sweden. Among these, 138 (2.3%) children only in
