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The existing information supports the use of this material as described in this safety assessment. Octyl isobutyrate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog hexyl isobutyrate (CAS # 2349-07-7) show that octyl isobutyrate is
Background and AimsOlder persons with problematic alcohol use vary in psychosocial functioning, age of onset for problem drinking and use of other drugs. The study measured the differential risks of all-cause, alcohol, polydrug and psychiatric-related repeated hospitalizations among older persons with problematic alcohol use.DesignA linked register-based cohort study with discontinuous multiple-fa
Adopting a human rights-based approach to examining law, policy and practice relating to displacement in the context of disasters and climate change highlights gaps between international and national standards, and realities on the ground.
Climate Change, Disasters and the Refugee Convention is concerned with refugee status determination (RSD) in the context of disasters and climate change. It demonstrates that the legal predicament of people who seek refugee status in this connection has been inconsistently addressed by judicial bodies in leading refugee law jurisdictions, and identifies epistemological as well as doctrinal impedim
This paper examines how and why the Norwegian government’s early handling of the Covid-19 pandemic became constructed as a centre–periphery issue in public discourse. By analysing opinion pieces and editorials published in a North Norwegian regional newspaper during the first months of the outbreak, it identifies how a ‘northern peripherality’ discourse emerged and highlighted geographical, infras
X-ray fluorescence microscopy performed at nanofocusing synchrotron beamlines produces quantitative elemental distribution maps at unprecedented resolution (down to a few tens of nanometres), at the expense of relatively long measuring times and high absorbed doses. In this work, a method was implemented in which fast low-dose in-line holography was used to produce quantitative electron density ma
The narrative of the Western modernity is a story about technological progress where technology gradually has replaced humans in the world of work. Yet, the relationship between technology and humans is more complex than that. This is illustrated by Jeff Bezos’ idea of “Artificial Artificial Intelligence,” where humans are hired as stand-ins when automatized systems fail. Much has been said about The narrative of the Western modernity is a story about technological progress where technology gradually has replaced humans in the world of work. Yet, the relationship between technology and humans is more complex than that. This is illustrated by Jeff Bezos’ idea of “Artificial Artificial Intelligence,” where humans are hired as stand-ins when automatized systems fail. Much has been said about
Michael Way works at the NASA Goddard Institute for Space Studies where he is modeling planetary atmospheres, with a special interest for Venus and its history. He was visiting Lund Observatory to give a talk at the Källén Seminars for Young Astronomers recently, and we invited him onto the podcast to ask him if there is a chance that Venus has ever been habitable (Spoiler: the answer is 'yes').
Joining us on the Meridian today we have Colin Carlile, the former director of the Institut Laue-Langevin (ILL). He came to Sweden to head up the Swedish bid to locate the European Spallation Source here in Lund, and after formally retireing he did a master degree in astronomy here at Lund Observatory. In this second season of the Meridian we are also bringing you some field reporting from the No
This article examines the role of secrecy in relations between the NSU, the largest Danish national socialist youth organization, and parents. The NSU struggled to recruit and retain members from Danish families with and without national socialist convictions. By analysing how NSU media and internal correspondence framed parents’ reluctance to join, this article traces the changing functions of NS
Alla organisationers ledningar vill ha en verksamhet som når upp till det som deras styrdokumenten vill förmedla. Ledningen har med sina säkerhetspolicyer visat sin vilja och avsikt med säkerhetatsarbetet och förväntar sig att dessa styrdokument ger resultat. Är det så enkelt? Kan ledningarna bli framgångsrikare gällande efterlevnad? Genom att ta reda på vad säkerhetspolicyer innehåller och om inn
PURPOSE: Epinephrine is used in local anesthetics to induce vasoconstriction and thus reduce bleeding and prolong the anesthetic effect. Finding the optimal delay between the administration of the anesthetic and skin incision to ensure vasoconstriction and minimize bleeding is important and has recently become the subject of debate. This is the first study to assess blood perfusion and oxygen satu
Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SRμCT) has become a tool for extending the imaging of two-dimensional thin sections into three-dimensional imaging of tissue blocks, enabling so-called virtual histology with arbitrary clipping planes, volumetric renderi
BACKGROUND: Over the past decades, the focus on the regenerative properties of platelets (PLTs) has intensified and many PLT-derived growth factors are readily used in medical settings. A general lack of standardization in the preparation of these growth factors remains, however, and this study therefore examines the dynamics of growth factors throughout the freeze-thaw procedure.STUDY DESIGN AND
BACKGROUND: Platelet lysate is a readily available source of growth factors, and other mediators, which has been used in a variety of clinical applications. However, the product remains poorly standardized and the present investigation evaluates the composition of platelet lysate obtained from either fresh or stored pathogen-inactivated platelet units.MATERIALS AND METHODS: Platelet pooled units (
Estrogen receptor alpha (ERα, encoded by ESR1) is a well-characterized transcription factor expressed in more than 75% of breast tumors and is the key biomarker to direct endocrine therapies. On the other hand, much less is known about estrogen receptor beta (ERβ, encoded by ESR2) and its importance in cancer. Previous studies had some disagreement, however most reports suggested a more favorable
Nature-based solutions (NBS) attract a growing interest in research and practice due to their potential to address climate change while improving human health and well-being and safeguarding biodiversity. The integration of the NBS concept in urban governance, however, is still emerging and it faces regulatory, political, financial and cognitive barriers. While the literature acknowledges an incre
Electric vehicles could help reduce greenhouse gas emissions and deliver a sustainable transport system. But the full life cycle of electric vehicles needs to be considered in order to avoid creating resource issues while trying to achieve the necessary climate goals.
